Protein Alignment DUBAI and USP46

DIOPT Version :9

• Sequence 1: NP_610784.1
• Gene: DUBAI / 36361
• FlyBaseID: FBgn0033738
• Length: 852
• Species: Drosophila melanogaster
• Sequence 2: NP_073743.2
• Gene: USP46 / 64854
• HGNCID: 20075
• Length: 366
• Species: Homo sapiens
• Alignment Length: 408
• Identity: 113/408 - (27%)
• Similarity: 167/408 - (40%)
• Gaps: 107/408 - (26%)

  Fly   359 GLVNLGNTCYMNSVLQALAMTSDFSRQILLIECNSVLLMKVQQQ--------IALMHHSLRYE-- 413
            ||||.|||||.|||||||.....|.        .:||..|.||:        :|.:.||:..:
Human    36 GLVNFGNTCYCNSVLQALYFCRPFR--------ENVLAYKAQQKKKENLLTCLADLFHSIATQKK 92

  Fly   414 ----LTPSRVLNATRPPS--FTPGLQQDSSEFLGYLLDLLHEHEINSSSVTGHSVGPPKTGREVD 472
                :.|.:.::..|..:  |...:|||:.|||.|||:.:
Human    93 KVGVIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLLNTI------------------------- 132

  Fly   473 DVPALLSEDILSSGVIPYNSKDHELSSGSNSDNCNHKPTPTPPATPTKATNGLKQQGQQVDQAKP 537
                   .|||.      ..|..|..:|                   |..||  ...:..:..||
Human   133 -------ADILQ------EEKKQEKQNG-------------------KLKNG--NMNEPAENNKP 163

  Fly   538 PST-IDKTFAGKLSTTYRCLNCGWESRNEDSFRELQLSFPDDKEDCGATNYSVQDLIEYYCSPEK 601
            ..| :.:.|.|.|:...|||||...|..::.|.:|.:    |.|.    |.|:...:..:.:.|.
Human   164 ELTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLSV----DVEQ----NTSITHCLRDFSNTET 220

  Fly   602 LDGDNQYFCPQCKKLCDAERHIGVTQAPKNLILTLKQFKYDQKYHFRTKLMHKVFHDESVTVKMS 666
            |..:.:|:|..|....:|::.:.|.:.|..|.|.||:|||.::.|..|||.::|.....:.:..:
Human   221 LCSEQKYYCETCCSKQEAQKRMRVKKLPMILALHLKRFKYMEQLHRYTKLSYRVVFPLELRLFNT 285

  Fly   667 AKD--SLQEMSTVHYDLYAGVVHAGYSMDSGHYFTFAADQAKNWYKFNDNVVTH---SKPEEMHN 726
            :.|  :|..|    |||.|.|||.|...:.|||.|...... .|..|:|::|..   ...||.:.
Human   286 SSDAVNLDRM----YDLVAVVVHCGSGPNRGHYITIVKSHG-FWLLFDDDIVEKIDAQAIEEFYG 345

  Fly   727 LTS-----PNTPYILFYK 739
            |||     ..:.|||||:
Human   346 LTSDISKNSESGYILFYQ 363

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DUBAI	NP_610784.1	UCH	358..738	CDD:278850	111/405 (27%)
		Peptidase_C19H	359..739	CDD:239129	112/406 (28%)
USP46	NP_073743.2	Peptidase_C19G	36..363	CDD:239128	112/406 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1864
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810