Protein Alignment DUBAI and Usp35

DIOPT Version :9

• Sequence 1: NP_610784.1
• Gene: DUBAI / 36361
• FlyBaseID: FBgn0033738
• Length: 852
• Species: Drosophila melanogaster
• Sequence 2: XP_006507886.1
• Gene: Usp35 / 244144
• MGIID: 2685339
• Length: 1072
• Species: Mus musculus
• Alignment Length: 1049
• Identity: 270/1049 - (25%)
• Similarity: 417/1049 - (39%)
• Gaps: 345/1049 - (32%)

  Fly    19 GGAGNGIPPNAKPMSANGMANAEENVLPKGMDTGSPAGESLNS-----------NRSGK---RDI 69
            ||||   ||.|:.::.   ......:||.|     ||.:.:.:           .|.|.   ..:
Mouse   154 GGAG---PPGARALAC---VQLGLQLLPDG-----PAADEVFALLRREVLRTVCERPGPAACAQV 207

  Fly    70 KALLAYLQSIDMPEQGHNVMAICERVIVDLARLQIP----RGASCPRLKEDVCQVGAFLAT--RN 128
            ..|||..... :|:..|.:: .|::::..|.|.:.|    .||  ....|...||...||.  |.
Mouse   208 ARLLARHPRC-VPDGAHRLL-FCQQLVRCLGRFRCPAEGEEGA--VEFLEQAQQVSGLLAQLWRA 268

  Fly   129 EKFHQMFYLRVVYELITKSPFEPPPSCAVAIVFQLFDSTQILEAVHSLL--EQNVQDSSIKKTVN 191
            :....:..|:.::.:|:.:..|||.|...::|..|  ..::::.|...|  :.:|.||.:...::
Mouse   269 QPAAILPCLKELFAVISCTEEEPPSSALASVVQHL--PLELMDGVVRNLSNDDSVTDSQMLTAIS 331

  Fly   192 LLCDWITYCTFCSTLNLWVLALLKGLRDQGKMALLDEIAMDNIEKLFHVMIFPALRQKAAPVVFH 256
            .:.||::: .....::.|::||||||....|.::|.|:::..|||:|..:::|.:|..|..|:.:
Mouse   332 RMIDWVSW-PLGKNIDKWIIALLKGLAAVKKFSILIEVSLAKIEKVFSKLLYPIVRGAALSVLKY 395

  Fly   257 MLSTINQTPEVFHKILPRIP-RVLQYVKNQSTTMDEIGLETKKCLQQLVDLTSALMLRFYDQDEL 320
            ||.|...:.|.||.:||.|| .|...||..|.:       ...||:||.:|...::.||....:|
Mouse   396 MLLTFQHSHEAFHLLLPHIPAMVASLVKEDSNS-------GTSCLEQLAELVHCMVFRFPGFPDL 453

  Fly   321 YVATKKALQTYEPSPNCVALAKAMHENAQPWGRRNA----------------RVGLVNLGNTCYM 369
            |....:|::... .||...:.:.:.::|  |..:.:                ::||:|||||||:
Mouse   454 YEPVMEAIKDLH-IPNEDRIKQLLGQDA--WTSQKSELAGFYPRLMAKSDTGKIGLINLGNTCYV 515

  Fly   370 NSVLQALAMTSDFSRQIL-LIECNSVLLM-KVQQQIALMHHSLRYELTPSRVLNATRPPSFTPGL 432
            |||||||.|.|||...:| |.|.||..|| |:|...|.:.||.|..::|...|:|:..|.|:||.
Mouse   516 NSVLQALFMASDFRHCVLRLTENNSQPLMTKLQWLFAFLEHSQRPAISPENFLSASWTPWFSPGT 580

  Fly   433 QQDSSEFLGYLLDLLHEHEINSSSVTGHSVGPPKTGREVDDVPALLSEDILSSGVIPYNSKDHEL 497
            |||.||:|.||||.|||.|              |||..:
Mouse   581 QQDCSEYLKYLLDRLHEEE--------------KTGMRI-------------------------- 605

  Fly   498 SSGSNSDNCNHKPTPTPPATPTKATNGLKQQGQQVDQAKPPS----TIDKTFAGKLSTTYRCLNC 558
                    |..                |||......|.:.||    :::|.|.||:.|...||:|
Mouse   606 --------CQK----------------LKQSSLPSPQEELPSSNATSVEKMFGGKIVTRICCLHC 646

  Fly   559 GWESRNEDSFRELQLSFP----------------------------------------------- 576
            ...|..|::|.:|.|:||
Mouse   647 LNVSSREEAFTDLSLAFPPPERSRHRRLGSVMLPTEDVRVQELTLAPRAPGAQRQRKRCITGDAP 711

  Fly   577 --------------------------------------------------------------DDK 579
                                                                          |:|
Mouse   712 RTGLDSEGVDTIGTGGRSGQEKVEREQAGKEKEVAEDREEEGTREEEKEEGEEKDKEKEKKEDEK 776

  Fly   580 E-----------------------------DCGAT-NYSVQDLIEYYCSPEKLDGDNQYFCPQCK 614
            |                             .||.. :.||.||:.|:.|||:|..:|:|:|..|.
Mouse   777 EKEAENGKEKEGDSLGPGTHREAATPPREQTCGPEGSRSVLDLVNYFLSPERLTAENRYYCESCA 841

  Fly   615 KLCDAERHIGVTQAPKNLILTLKQFKYDQKYHFRTKLMHKVFHDESVTVKMSAKDSLQEMSTVHY 679
            .|.|||:.:.::|.|:.|||||.:|.:|    .||....|:..|  ||:.:..:..|.......|
Mouse   842 SLQDAEKVVELSQGPRYLILTLLRFSFD----LRTMRRRKILDD--VTIPLLLRLPLAGGQGQAY 900

  Fly   680 DLYAGVVHAGYSMDSGHYFTFAADQA----------------KNWYKFNDNVVTHSKPEEMHNLT 728
            ||.:.|||:|.|.:||||:.:|.:.|                ..||.|||..|::|..|.:.|:|
Mouse   901 DLCSVVVHSGVSSESGHYYCYAREGAARPAPVLGSTERPEPENQWYLFNDTRVSYSSFESVSNVT 965

  Fly   729 S---PNTPYILFYKMCGHSNESNSVTASCSSSMVSGSNDQVVSVPLSPPLKLE-ELPRRLRDYVR 789
            |   .:|.|:|||:                    ....:...:.|.||.::.| .|.:.|.:.:.
Mouse   966 SFFPKDTAYVLFYR--------------------QRPREDPAAEPGSPRVRAEPTLHKDLMEAIS 1010

  Fly   790 KDNHVYNEELKMQRFKRGNSGHGNAFVSR--------HNFDGDGDEDDKAPPPPGGC---GGNGL 843
            |||.:|.:|.:.:...|.      |::|.        ..||.|.|||:.:   ||||   ||||
Mouse  1011 KDNVLYLQEQEKEARSRA------AYISTLPAPPHWGRGFDEDKDEDEGS---PGGCNPAGGNG- 1065

  Fly   844 GMNINRFVF 852
              :.:|.||
Mouse  1066 --DFHRLVF 1072

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DUBAI	NP_610784.1	UCH	358..738	CDD:278850	145/543 (27%)
		Peptidase_C19H	359..739	CDD:239129	146/543 (27%)
Usp35	XP_006507886.1	Peptidase_C19	505..979	CDD:351799	146/543 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	213	1.000	Domainoid score	I2742
eggNOG	1	0.900	-	-		E1_KOG1864
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H35459
Inparanoid	1	1.050	308	1.000	Inparanoid score	I2592
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG56146
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004017
OrthoInspector	1	1.000	-	-		otm42866
orthoMCL	1	0.900	-	-		OOG6_105906
Panther	1	1.100	-	-	O	PTHR24006
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3301
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.870