Protein Alignment Nup54 and nup54

DIOPT Version :10

• Sequence 1: NP_610783.1
• Gene: Nup54 / 36360
• FlyBaseID: FBgn0033737
• Length: 610
• Species: Drosophila melanogaster
• Sequence 2: NP_001017349.1
• Gene: nup54 / 550103
• XenbaseID: XB-GENE-948035
• Length: 536
• Species: Xenopus tropicalis
• Alignment Length: 583
• Identity: 220/583 - (37%)
• Similarity: 317/583 - (54%)
• Gaps: 82/583 - (14%)

  Fly    41 FGAQATSTPAFGAQPATSAFGAGSAFGATAAAPAFGAATGTSAFGGSAFGSTPAFGAATTTTAGT 105
            ||| :|.||   |...|:.|..|:          |...|.||.||   ||:       |||||.|
 Frog     5 FGA-STGTP---ANQGTTGFSLGT----------FTPKTTTSGFG---FGT-------TTTTAST 45

  Fly   106 GLGGGGFGGFGAAPATSQAGLFGAPATSAAPPAFSGFGQQAAASTAPASGFSGFGTTTTSAPAFG 170
            |. ||||||||                                :|..||..|.|..||.:....|
 Frog    46 GF-GGGFGGFG--------------------------------TTTTASTGSAFSFTTPANTTSG 77

  Fly   171 GFGTSQSTGFG-GGAFGSTFGKPANTTVTPGFG-GFGGTSFMLGQPQQQPAPISADEAFAQSILN 233
            .||.:|:.||| |..||||   ..||.:..|.| |.|.:.|...|.|||..|:.....|.||:.:
 Frog    78 LFGATQNKGFGFGTGFGST---TTNTGLGTGLGTGLGFSGFNTSQQQQQQQPVIGCGLFNQSVQS 139

  Fly   234 V----------------SIFGDERDKIVAKWNYLQATWGTGKMFYSQSAAPVDITPENVMCRFKA 282
            .                ::.|||||.|:||||.|||.|||||.|:..:..||:.|.||..|||||
 Frog   140 TPQSNQLINTASALSAPTLLGDERDAILAKWNQLQAFWGTGKGFFMNNTPPVEFTQENPFCRFKA 204

  Fly   283 IGYSRMPGKDNKLGLVALNFCRELSAVKPHQQQVIQTLHSLFGSKPNMLVHIDSIKELENKKCQI 347
            :|:|.:|...::.||::|.|.::.|.::..|||::::||.:.|....:.|:::.:|...:.:.::
 Frog   205 VGFSYIPNNKDEDGLISLIFNKKESDIRGQQQQLVESLHKVLGGHQTLTVNVEGVKTKADDQTEV 269

  Fly   348 VIYVEEKLQHAPN-ESKRILATELSNYLNQATLKPQLNNLGVVEALALVLPDEDQLREYLENPPR 411
            :|||.|:   :|| .|:|:.|:.|.:|..||.:|..|..|||..|:|.......|:::.::|||.
 Frog   270 IIYVVER---SPNGTSRRVGASALFSYFEQAHIKTNLQQLGVTGAMARTELSPAQIKQLIQNPPS 331

  Fly   412 GVDPRMWRQANSDNPDPTLYIPVPMVGFNDLKWRVKCQEQETDTHALYIKKVESELTELKKRHAT 476
            ||||.:|.||..|||||...|||||:||.:|..|::.|:|.|..|...:..:..::.||:|..||
 Frog   332 GVDPIIWEQAKVDNPDPERLIPVPMIGFKELLRRLEVQDQMTKQHQSRLDIISEDIGELQKNQAT 396

  Fly   477 ATAKILEHKRKLAELSHRILRIIVKQECTRKVGTSLTPEEEALRTKLQNMLAVVSAPTQFKGRLS 541
            ..|||.::||||.|||||:|::::|||..||.|.::..|||.||.:|..:.:.::|||||||||:
 Frog   397 TMAKIGQYKRKLMELSHRVLQVLIKQEIQRKSGFAIQAEEEQLRVQLDTIQSELNAPTQFKGRLN 461

  Fly   542 ELLSQMRMQRNQFAANGGAEYALDKEAEDEMKTFLTMQQRAMEVLSDTVNKDLRALDVIIKGL 604
            ||:||:|||.:..|.....:|.:|.:...|:|..|..||..:..|...:..:|..:.:|.:||
 Frog   462 ELMSQIRMQNHFGAVRSEEKYYVDADLLREIKQHLKQQQEGLSHLIGIIKDNLEDIKLIEQGL 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nup54	NP_610783.1	Nucleoporin_FG	2..91	CDD:463941	17/49 (35%)
		Nucleoporin_FG	125..220	CDD:463941	30/96 (31%)
		Nup54	409..546	CDD:464011	68/136 (50%)
		Nup54_C	562..600	CDD:465767	9/37 (24%)
nup54	NP_001017349.1	Nup54	329..466	CDD:464011	68/136 (50%)
		Nup54_C	482..520	CDD:465767	9/37 (24%)