Protein Alignment Nup54 and nup44

DIOPT Version :10

• Sequence 1: NP_610783.1
• Gene: Nup54 / 36360
• FlyBaseID: FBgn0033737
• Length: 610
• Species: Drosophila melanogaster
• Sequence 2: NP_595981.1
• Gene: nup44 / 2540775
• PomBaseID: SPBC19G7.15
• Length: 403
• Species: Schizosaccharomyces pombe
• Alignment Length: 491
• Identity: 117/491 - (23%)
• Similarity: 197/491 - (40%)
• Gaps: 129/491 - (26%)

  Fly   138 AFSGFGQQAAASTAPASGFSG-FGTTTTSAPAFGGFGTSQSTGFGGGA-FGST-----FGKPANT 195
            ||| ||||.::..||:.|.:| ||.:.|:.|         :..||.|: ||||     .|.|..:
pombe     2 AFS-FGQQGSSIKAPSIGSTGVFGQSNTTKP---------TAPFGSGSIFGSTNTNVGAGGPTGS 56

  Fly   196 TVTPGFGGFGGTSFMLGQPQQQPAPISADEAFAQSILNV---SIFGDERDKIVAKWNYLQA-TWG 256
            :..|.||     :.:.|:.||||.     .:|:.:..|.   ::||..........|.... :|.
pombe    57 SSAPPFG-----NSIFGKTQQQPT-----TSFSNTTTNAPQSTVFGQNAASRTGNSNTQPLFSWS 111

  Fly   257 TGKMFYSQSAAPVDITPENVMCRFKAIGYSRMPGKDNKLGLVALNFCRELSAVKPHQQQVIQTLH 321
            |    .:....|||                                  |.:|..|      .:|.
pombe   112 T----VNNPTKPVD----------------------------------ETNATIP------SSLL 132

  Fly   322 SLFGSKPNMLVHIDSIKELENKKCQIVIYVEEKLQHAPNESKRILATELSNYLNQATLKPQLNNL 386
            ...|..||..|........:...      |||::|       :||.....|:.:.|..:...|.:
pombe   133 LSSGISPNATVSNAQYGPAQPPS------VEEQVQ-------KILNAWNLNHPDCAFQRFFYNKV 184

  Fly   387 GVVEALALVLPDEDQLREYLENPPRGVDPRMWRQANSDNPDPTLYIPVPMVGFNDLKWRVKCQEQ 451
            .|.:|...|            .|| ..:.:.|.:|.::.|..:: :||..|||.|::.|:..|.|
pombe   185 PVEQAALYV------------KPP-NYNQQKWDEAVANRPSNSV-VPVLAVGFPDVQKRINMQIQ 235

  Fly   452 ETDTHALYIKKVESELTELKKRH-ATATAKILEHKRKLAELSHRILRIIVKQECTRKVGTSLTPE 515
            :.:|:.:.::::...|..|..:| ...:.|:.|.|.:...||.||||:.:|....|..|.:|.|.
pombe   236 QVNTYRIRMREIVETLGRLSNKHDLDFSIKLAEAKNRHVRLSERILRLAIKVHVLRHRGYALKPN 300

  Fly   516 EEALRTKLQNMLAVVSAPTQFKGRLSELLSQMRM----------QRNQFAANGGAEYALDKEAED 570
            ||.||.||.::...::.|..| |||:|:.:::.:          ||:.. |.|..::   ::..|
pombe   301 EEELRKKLDDLTKSLNNPEIF-GRLNEIWARITLIFEGEKISEDQRSNL-AKGVVDW---RKNSD 360

  Fly   571 EMKTFLTMQQRAMEVLSDTVNKDLRALDVIIKGLPE 606
            :           :||::|.:......|..::|.:.|
pombe   361 Q-----------LEVITDVLRDHQVGLSYVVKLMQE 385

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nup54	NP_610783.1	Nucleoporin_FG	2..91	CDD:463941
		Nucleoporin_FG	125..220	CDD:463941	32/88 (36%)
		Nup54	409..546	CDD:464011	44/137 (32%)
		Nup54_C	562..600	CDD:465767	5/37 (14%)
nup44	NP_595981.1	Nucleoporin_FG	3..108	CDD:463941	36/124 (29%)
		Nup54	194..330	CDD:464011	44/138 (32%)