DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8520 and AT4G30490

DIOPT Version :9

Sequence 1:	NP_001188911.1	Gene:	CG8520 / 36357	FlyBaseID:	FBgn0033734	Length:	458	Species:	Drosophila melanogaster
Sequence 2:	NP_567847.1	Gene:	AT4G30490 / 829172	AraportID:	AT4G30490	Length:	497	Species:	Arabidopsis thaliana

Alignment Length:	446	Identity:	160/446 - (35%)
Similarity:	242/446 - (54%)	Gaps:	65/446 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 PLKEYEKRVSSGQLMT-DNRQLQTMKELDALYH---------KIQGYKPSYRAGGGGGGFFSSIF 86
            ||.|||:|:|:|:||| |..|:..::||..||.         ::..|..|.:: .....|:|.:.
plant    90 PLVEYERRISNGELMTGDICQISALRELQRLYDELVDSVDTCRLDRYNTSDKS-SRSRWFWSRLM 153

  Fly    87 GRKSSTEDDDQDDPNAGSHAP-QGLYLYGSVGVGKTTLMDLFFDCCTQIHRKQRVHFTSFMNTVH 150
            .:.              |::| :||||||.||.|||.|||||||......:|||:||..||.:||
plant   154 PQT--------------SYSPVKGLYLYGGVGTGKTMLMDLFFDQLPCTWKKQRIHFHDFMLSVH 204

  Fly   151 TRIHEAKQRQGPVDRAFNSEKPAPFDPTKPVADLIASESWLICFDEFQVTDIADAMVLKRLFTHL 215
            :|:.:.|...               ||.:.||..||.::.|:|.|||.|||:|||::|.|||.||
plant   205 SRLQKHKGLS---------------DPLEVVAQEIAHDAILLCLDEFMVTDVADALILNRLFGHL 254

  Fly   216 FRHGIVVVATSNRHPEDLYKNGLQRTNFLPFIALLQRRCKVSQLDS-IDYRRIAQSGDTNYFVKG 279
            |.:|:::||||||:|:.||:.||||..|||||:.|:.|..|.::.| :|||::..:....||: |
plant   255 FSNGVILVATSNRNPDKLYEGGLQRDLFLPFISSLKERSVVHEIGSAVDYRKLTSAEQGFYFI-G 318

  Fly   280 QTDADGSMNRMFKILCAEENDIIRPRTL-THFGRDLTFNRTCGQVLDSTFSELCDRPLAGSDFLQ 343
            : |....:.:.|:.|.. :|.:.||:.: ...||.|.............|.|||||||..:|:..
plant   319 K-DLSTLLKQKFRQLIG-DNVVARPQVVEVVMGRKLQIPLGANGCAYFPFEELCDRPLGAADYFG 381

  Fly   344 ISQFFHTVLIRDVPQLTLDVKAQMRRFITLIDTLYNNRVRVVISSDV----ALENLFSFTG---- 400
            :.:.|||:.:.::|...|..:....||:||:|.:|.||.|::.:::.    .||.:.:.:.
plant   382 LFKKFHTLALDEIPVFGLHNRTAAYRFVTLVDVMYENRARLLCTAEANPQELLEKIITISEAKSM 446

  Fly   401 GSKTLSDSERTLMDDLNIKESKASFFTGEEEL-FAFDRTLSRLYEMQKREYWEQWA 455
            |.:|.|.|.:..:.:|.:          :.|| ||.|||:|||.||..:||.|..|
plant   447 GPRTSSRSRKNDVTELCV----------DNELGFAKDRTISRLTEMNSKEYLEHHA 492

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8520	NP_001188911.1	YhcM	22..450	CDD:224402	156/439 (36%)
CG8520	NP_001188911.1	P-loop_NTPase	31..450	CDD:304359	156/439 (36%)
AT4G30490	NP_567847.1	YhcM	90..490	CDD:224402	158/442 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	221	1.000	Domainoid score	I714
eggNOG	1	0.900	-	-		E1_COG1485
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H5782
Inparanoid	1	1.050	239	1.000	Inparanoid score	I1089
OMA	1	1.010	-	-		QHG54198
OrthoDB	1	1.010	-	-		D702840at2759
OrthoFinder	1	1.000	-	-		FOG0003120
OrthoInspector	1	1.000	-	-		otm3532
orthoMCL	1	0.900	-	-		OOG6_101377
Panther	1	1.100	-	-	O	PTHR12169
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2090
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.930