DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8520 and AT4G28070

DIOPT Version :9

Sequence 1:	NP_001188911.1	Gene:	CG8520 / 36357	FlyBaseID:	FBgn0033734	Length:	458	Species:	Drosophila melanogaster
Sequence 2:	NP_001031737.1	Gene:	AT4G28070 / 828922	AraportID:	AT4G28070	Length:	473	Species:	Arabidopsis thaliana

Alignment Length:	457	Identity:	163/457 - (35%)
Similarity:	244/457 - (53%)	Gaps:	70/457 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 HMSG----LSPLKEYEKRVSSGQLMT-DNRQLQTMKELDALYH---------KIQGYKPSYRAGG 76
            |.:|    ..||.|||:|:.:|:|:. |..||.|::||..||.         ::..|..|  |..
plant    52 HSNGDGKIAGPLVEYERRIVAGELLDGDLCQLGTLRELQRLYDELVQSADACRLDRYSAS--AKS 114

  Fly    77 GGGGFFSSIFGRKSSTEDDDQDDPNAGSHAP-QGLYLYGSVGVGKTTLMDLFFDCCTQIHRKQRV 140
            ....:|.:.|...||.             :| :||||||.||.|||.||||||.......|.||:
plant   115 TRSNWFWNKFVSHSSV-------------SPVKGLYLYGGVGTGKTMLMDLFFHQLPASWRTQRI 166

  Fly   141 HFTSFMNTVHTRIHEAKQRQGPVDRAFNSEKPAPFDPTKPVADLIASESWLICFDEFQVTDIADA 205
            ||.:||.:||:|:.:.|..:               ||.:.|...||.|:.|:|.|||.|.|:|||
plant   167 HFHNFMLSVHSRLQKHKGLE---------------DPLEVVGLEIADEAILLCLDEFMVNDVADA 216

  Fly   206 MVLKRLFTHLFRHGIVVVATSNRHPEDLYKNGLQRTNFLPFIALLQRRCKVSQL-DSIDYRRIAQ 269
            ::|.|||.|||.:||::||||||.|::||:.||||..|||||:.|:.||.|.:: .|:|||::..
plant   217 LILNRLFRHLFNNGIILVATSNRAPDNLYEGGLQRDLFLPFISTLKERCVVREIGSSVDYRKLTS 281

  Fly   270 SGDTNYFVKGQTDADGSMNRMFKILCAEENDIIRPRTL-THFGRDLTFNRTCGQVLDSTFSELCD 333
            :.:..||: |: |..|.:.:.|::|..::.  ..|:.: ...||.|.............|.||||
plant   282 AEEGFYFI-GK-DISGLLKQKFQLLVGDQP--AGPQVVEVVMGRKLQVPLAADGCAYFLFEELCD 342

  Fly   334 RPLAGSDFLQISQFFHTVLIRDVPQLTLDVKAQMRRFITLIDTLYNNRVRVVISSDVA----LEN 394
            |||..:|:|.:.:.|||:.:..||...|..:....||:||:|.:|.|:.|::.:::.:    ||.
plant   343 RPLGAADYLGLFKKFHTLALEGVPFFGLHNRTAAYRFVTLVDVMYENKARLLCTAEGSPLELLER 407

  Fly   395 LFSFTGGS----KTLSDSERTLMDDLNIKESKASFFTGEEEL-FAFDRTLSRLYEMQKREYWEQW 454
            :.:.:...    :|.|.|.::...||.:          :.|| ||.|||:|||.||..:||.||.
plant   408 IVTISDAQQIAPRTSSRSRKSDDPDLCV----------DNELGFAKDRTISRLTEMNSKEYLEQH 462

  Fly   455 AK 456
            ::
plant   463 SR 464

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8520	NP_001188911.1	YhcM	22..450	CDD:224402	159/449 (35%)
CG8520	NP_001188911.1	P-loop_NTPase	31..450	CDD:304359	157/440 (36%)
AT4G28070	NP_001031737.1	YhcM	62..464	CDD:224402	161/445 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	221	1.000	Domainoid score	I714
eggNOG	1	0.900	-	-		E1_COG1485
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H5782
Inparanoid	1	1.050	239	1.000	Inparanoid score	I1089
OMA	1	1.010	-	-		QHG54198
OrthoDB	1	1.010	-	-		D702840at2759
OrthoFinder	1	1.000	-	-		FOG0003120
OrthoInspector	1	1.000	-	-		otm3532
orthoMCL	1	0.900	-	-		OOG6_101377
Panther	1	1.100	-	-	LDO	PTHR12169
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2090
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.930