DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8834 and OPCL1

DIOPT Version :9

Sequence 1:	NP_610779.1	Gene:	CG8834 / 36356	FlyBaseID:	FBgn0033733	Length:	535	Species:	Drosophila melanogaster
Sequence 2:	NP_564115.1	Gene:	OPCL1 / 838639	AraportID:	AT1G20510	Length:	546	Species:	Arabidopsis thaliana

Alignment Length:	542	Identity:	151/542 - (27%)
Similarity:	235/542 - (43%)	Gaps:	68/542 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 TTYNEKDNIWSGAKRNSIYNYDTSVGKIIFNNMKNWPKNVCQICDVDGVTVTFEQGLTWSI--RI 68
            ||:     |.|.|.|..|...|.|.|:                      .:||.:  .|..  .:
plant    35 TTF-----ISSQAHRGRIAFIDASTGQ----------------------NLTFTE--LWRAVESV 70

  Fly    69 AQYLKKRGLNHKDVIGIAAKNSTYVMPLGVACLMNGTPFHSVNPVLDDATLTHVFSITKPTLIFC 133
            |..|.:.|:....|:.:.:.||.....:.::.:..|....:.||:.....:......:.|.|.|.
plant    71 ADCLSEIGIRKGHVVLLLSPNSILFPVVCLSVMSLGAIITTTNPLNTSNEIAKQIKDSNPVLAFT 135

  Fly   134 DGQEYDKVHKATVGWHPEILTLTDHVEGVQGIETLLDPTTTEKIYQPEVLKEGGDQ--TVAILCS 196
            ..|...|: .|.....|.:|...:.|:.|..:..|::....|.  ....:||..||  |..:|.|
plant   136 TSQLLPKI-SAAAKKLPIVLMDEERVDSVGDVRRLVEMMKKEP--SGNRVKERVDQDDTATLLYS 197

  Fly   197 SGTTGLPKAVCISNSILIQ--------------DSMLITSQSVIYVGSCLDWITGLWAFVFSTVF 247
            |||||:.|.|..|:..||.              :...|.:..:.::.....:.|||.|      :
plant   198 SGTTGMSKGVISSHRNLIAMVQTIVNRFGSDDGEQRFICTVPMFHIYGLAAFATGLLA------Y 256

  Fly   248 GCTRIISNKAFTPEYFVGLVKKYKINYAVLPPRHLSALITCPD---AKPDALAPITHLNYGGGSI 309
            |.|.|:.:| |.....:..:.||:.....|.|..|.|::...|   ||.| |:.:..:..||..:
plant   257 GSTIIVLSK-FEMHEMMSAIGKYQATSLPLVPPILVAMVNGADQIKAKYD-LSSMHTVLCGGAPL 319

  Fly   310 SLATLQRSQELCKTAMFNSGYGMTE---VGAITINIGIS-NVSSAGRPVPGIKIRIVDE-DGKSL 369
            |....:...|...|.....|||:||   :||.|..:..| ...:||:....::.||||. .|:.|
plant   320 SKEVTEGFAEKYPTVKILQGYGLTESTGIGASTDTVEESRRYGTAGKLSASMEGRIVDPVTGQIL 384

  Fly   370 GYNQVGEIYVHTGQAWNGYYGNPVETRRMQDFEGWFHTGDLGYFDEQNFLYIVDRKKEILKYNGL 434
            |..|.||:::.......||:.|...|....|.|||..||||.|.||..|:::|||.||::||.|.
plant   385 GPKQTGELWLKGPSIMKGYFSNEEATSSTLDSEGWLRTGDLCYIDEDGFIFVVDRLKELIKYKGY 449

  Fly   435 HYWPTEIETVIAELSQVQDVCVVGIYDEREGDAAGALVVKSKGATISAKEIVEHVAKRLPATQKQ 499
            ...|.|:|.::....::.|..|:...|:..|....|.||:..|:::|.|.|:|.|||:: |..|:
plant   450 QVAPAELEALLLTHPEITDAAVIPFPDKEVGQFPMAYVVRKTGSSLSEKTIMEFVAKQV-APYKR 513

  Fly   500 LRAGVQFTDKLPANVNGKTMRK 521
            :|. |.|...:|.|.:||.:||
plant   514 IRK-VAFVSSIPKNPSGKILRK 534

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8834	NP_610779.1	CaiC	20..529	CDD:223395	146/528 (28%)
CG8834	NP_610779.1	AFD_class_I	46..519	CDD:302604	139/498 (28%)
OPCL1	NP_564115.1	4CL	26..536	CDD:341230	151/542 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24096
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.010