DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8834 and 4CL2

DIOPT Version :9

Sequence 1:	NP_610779.1	Gene:	CG8834 / 36356	FlyBaseID:	FBgn0033733	Length:	535	Species:	Drosophila melanogaster
Sequence 2:	NP_188761.1	Gene:	4CL2 / 821678	AraportID:	AT3G21240	Length:	556	Species:	Arabidopsis thaliana

Alignment Length:	537	Identity:	142/537 - (26%)
Similarity:	242/537 - (45%)	Gaps:	77/537 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 IFNNMKNWPKNVCQICDVDGVTVTFEQGLTWSIRIAQYLKKRGLNHKDVIGIAAKNSTYVMPLGV 98
            ||.|:..:....|.|....|...|:......|.::|..|...|:...||:.|...||..|:...:
plant    42 IFENISEFAAKPCLINGPTGEVYTYADVHVTSRKLAAGLHNLGVKQHDVVMILLPNSPEVVLTFL 106

  Fly    99 ACLMNGTPFHSVNPVLDDATLTHVFSITKPTLIFCDGQEYDKVHKATVGWHPEILTLTDHVEGV- 162
            |....|....|.||....|.::.....:...||....:..||:....   :..:|.:|...:.:
plant   107 AASFIGAITTSANPFFTPAEISKQAKASAAKLIVTQSRYVDKIKNLQ---NDGVLIVTTDSDAIP 168

  Fly   163 ----------QGIETLLDPTTTEKIYQPEVLKEGGDQTVAILCSSGTTGLPKAVCISNSILI--- 214
                      |..|..:| :..||| .||       ..||:..|||||||||.|.:::..|:
plant   169 ENCLRFSELTQSEEPRVD-SIPEKI-SPE-------DVVALPFSSGTTGLPKGVMLTHKGLVTSV 224

  Fly   215 --------------QDSMLITSQSVIYVGSCLDWITGLWAFVFSTVFGCT-RIISNKAFTPEYFV 264
                          :|.:::....:.::            :..:::..|: |:.:.....|::.:
plant   225 AQQVDGENPNLYFNRDDVILCVLPMFHI------------YALNSIMLCSLRVGATILIMPKFEI 277

  Fly   265 GL----VKKYKINYAVLPPRHLSALITCPDAKPDALAPITHLNYGGGSISLATLQRSQELCKTAM 325
            .|    :::.|:..|::.|..:.|:...|:.:...|:.:..:..|.     |.|.:..|...:|.
plant   278 TLLLEQIQRCKVTVAMVVPPIVLAIAKSPETEKYDLSSVRMVKSGA-----APLGKELEDAISAK 337

  Fly   326 F-----NSGYGMTEVG-AITINIGIS------NVSSAGRPVPGIKIRIVDED-GKSLGYNQVGEI 377
            |     ..||||||.| .:.:::|.:      ...:.|..|...:::|:|.| |.||..|:.|||
plant   338 FPNAKLGQGYGMTEAGPVLAMSLGFAKEPFPVKSGACGTVVRNAEMKILDPDTGDSLPRNKPGEI 402

  Fly   378 YVHTGQAWNGYYGNPVETRRMQDFEGWFHTGDLGYFDEQNFLYIVDRKKEILKYNGLHYWPTEIE 442
            .:...|...||..:|:.|....|.:||.||||:|:.|:.:.|:||||.||::||.|....|.|:|
plant   403 CIRGNQIMKGYLNDPLATASTIDKDGWLHTGDVGFIDDDDELFIVDRLKELIKYKGFQVAPAELE 467

  Fly   443 TVIAELSQVQDVCVVGIYDEREGDAAGALVVKSKGATISAKEIVEHVAKRLPATQKQLRAGVQFT 507
            :::....::.||.||.:.:|..|:...|.||:||.:.||..||.:.|:|:: ...|::.. |.||
plant   468 SLLIGHPEINDVAVVAMKEEDAGEVPVAFVVRSKDSNISEDEIKQFVSKQV-VFYKRINK-VFFT 530

  Fly   508 DKLPANVNGKTMRKTAR 524
            |.:|...:||.:||..|
plant   531 DSIPKAPSGKILRKDLR 547

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8834	NP_610779.1	CaiC	20..529	CDD:223395	142/537 (26%)
CG8834	NP_610779.1	AFD_class_I	46..519	CDD:302604	136/518 (26%)
4CL2	NP_188761.1	PLN02246	14..553	CDD:215137	142/537 (26%)
4CL2	NP_188761.1	4CL	32..546	CDD:213272	141/534 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24096
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.010