DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8834 and Slc27a5

DIOPT Version :9

Sequence 1:	NP_610779.1	Gene:	CG8834 / 36356	FlyBaseID:	FBgn0033733	Length:	535	Species:	Drosophila melanogaster
Sequence 2:	NP_077057.1	Gene:	Slc27a5 / 79111	RGDID:	708535	Length:	690	Species:	Rattus norvegicus

Alignment Length:	514	Identity:	115/514 - (22%)
Similarity:	199/514 - (38%)	Gaps:	79/514 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 PKNVCQIC-DVDGVTVTFEQGLTWSIRIAQYLKKRGLNHKDVIGIAAKNSTYVMP---------- 95
            |..|..:| ..:|.::|..:....:.:.|..||.: |....:.......:..|:|
  Rat   128 PDQVALVCTGSEGCSITNRELNAKACQAAWALKAK-LKEATIQEDKGATAILVLPSKSISALSVF 191

  Fly    96 LGVACLMNGTPFHSVNPVLDDATLTHVFSITKPTLIFCDGQEYDKVHKATVGWHPEILT------ 154
            ||:|.|  |.|...:||......|.|....:..:::..|....:.:.:..    |::|.
  Rat   192 LGLAKL--GCPVAWINPHSRGMPLLHSVQSSGASVLIVDPDLQENLEEVL----PKLLAENIRCF 250

  Fly   155 LTDHVEGVQGIETL---LDPTTTEKIYQPEVLKEG--GDQTVAILCSSGTTGLPKAVCISNSILI 214
            ...|.....|:|.|   ||...::.:  |..|:..  .......:.:||||||||...:|:..:|
  Rat   251 YLGHSSPTPGVEALGAALDAAPSDPV--PAKLRANIKWKSPAIFIYTSGTTGLPKPAILSHERVI 313

  Fly   215 QDSMLI-----TSQSVIYVGSCLDWITGLWAFVFSTV-FGCTRIISNKAFTPEYFVGLVKKYKIN 273
            |.|.::     |:..|:|....|....||...|...: .|.|.:::.| |:...:....::|.:.
  Rat   314 QMSNVLSFCGRTADDVVYNVLPLYHSMGLVLGVLGCLQLGATCVLAPK-FSASRYWAECRQYSVT 377

  Fly   274 YAVLPPRHLSALITCPDAKPDALAPITHLNYGGGSISLATLQRSQELCKTAMFNSGYGMTEVGAI 338
            ..:.....|..|...| .:|:..........|.| :.....:..|:..........||.||.
  Rat   378 VVLYVGEVLRYLCNVP-GQPEDKKHTVRFALGNG-LRADVWENFQQRFGPIQIWELYGSTEG--- 437

  Fly   339 TINIGISN-VSSAG------------RPVPGIKIRIVDEDGKSLGYNQVGEIYVHTG-------- 382
              |:|:.| |...|            .|:..::..|  |..:.:...|...|.|.||
  Rat   438 --NVGLMNYVGHCGAVGKTSCFIRMLTPLELVQFDI--ETAEPVRDKQGFCIPVETGKPGLLLTK 498

  Fly   383 ----QAWNGYYGNPVETRR------MQDFEGWFHTGDLGYFDEQNFLYIVDRKKEILKYNGLHYW 437
                |.:.||.|:..||:|      .|..:.:::|||:...|::.|.|..||..:..::.|.:..
  Rat   499 IRKNQPFLGYRGSQDETKRKLVANVRQVGDLYYNTGDVLALDQEGFFYFRDRLGDTFRWKGENVS 563

  Fly   438 PTEIETVIAELSQVQDVCVVGI-YDEREGDAAGALVVKSKGATISAKEIVEHVAKRLPA 495
            ..|:|.|::.|..:::|.|.|: ....||....|.|..:.|.|...:::.:||...|||
  Rat   564 TREVEGVLSILDFLEEVNVYGVTVPGCEGKVGMAAVKLAPGKTFDGQKLYQHVRSWLPA 622

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8834	NP_610779.1	CaiC	20..529	CDD:223395	115/514 (22%)
CG8834	NP_610779.1	AFD_class_I	46..519	CDD:302604	113/510 (22%)
Slc27a5	NP_077057.1	PRK08279	101..690	CDD:236217	115/514 (22%)
Slc27a5	NP_077057.1	AFD_class_I	140..680	CDD:302604	112/502 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166343045
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930