DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG8834 and Acsbg3

DIOPT Version :9

Sequence 1:NP_610779.1 Gene:CG8834 / 36356 FlyBaseID:FBgn0033733 Length:535 Species:Drosophila melanogaster
Sequence 2:NP_084417.1 Gene:Acsbg3 / 78625 MGIID:1925875 Length:705 Species:Mus musculus


Alignment Length:571 Identity:114/571 - (19%)
Similarity:202/571 - (35%) Gaps:189/571 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly    12 DNIWSGAKRNSIYNYDTSVGKIIFNNMKNWPKNVCQICDVDGVTVTFEQGLTWSIRIAQYLKKRG 76
            |.|.|.|.:   |::..::|.   ...|:|.            .:|:.:......|.|:...|.|
Mouse    77 DLIMSAATK---YSHYLAIGS---KYKKSWQ------------LLTYIEYYEACRRAAKAFLKVG 123

  Fly    77 LNHKDVIGIAAKNSTYVMPLGVACLMNG----TPFHSVNP----VLDDATLTHVF------SITK 127
            |.....:||...||:..:...:..:|.|    ....|::|    |:.:.:...:|      .:.|
Mouse   124 LERFHGVGIMGINSSEWVIASIGAIMAGGISVGILSSISPKACQVIAETSEMDIFVVDNDRQLQK 188

  Fly   128 PTLIFCDGQEYDKVHKATVGWHPEILTLTDHVEGVQGIETLLDPTTTEKIYQ-PEVLKEGGDQTV 191
            ...|    |.|.|..||.:.:..:|.....::...:|...|.|..:.||:.: .:.||.  :|..
Mouse   189 INQI----QGYLKHLKAIIQYREDIQEAQPNLYSWKGFLDLADGISDEKLDKIIDTLKP--NQCC 247

  Fly   192 AILCSSGTTGLPKAVCISNSILIQDSMLITSQSVI-----------------YVGSC------LD 233
            |::.:.||||..||:.:|:     |::..|:.:::                 |:..|      ||
Mouse   248 ALVYNQGTTGPSKAIMLSH-----DNITWTTAAIVQSLGFKCPPQGQEILVSYLPLCFPGIQILD 307

  Fly   234 -WI--------------TGLWA----------------------------------------FVF 243
             |:              :|.|:                                        |:.
Mouse   308 VWVAISVAGTVYFPSLDSGKWSGLPRTPGTGFLMELLREVQPTTFCGIPWVWDRMLDSLKTKFLD 372

  Fly   244 STVF-----------GC---TRIISNKAFTPEYFVGLVKKYKINYAVLPPRHLSALITCPDAKPD 294
            ||.|           |.   .:::..:...|..| ||.|:.....|    |....|..|..    
Mouse   373 STAFRRRIDHWAMRMGLHTNKKLMMGEIHQPLCF-GLAKRLTFERA----RKFLGLNHCQQ---- 428

  Fly   295 ALAPITHLNYGGG----------SISLATLQRSQELCKTAMFNSGYGMTE-VGAITI-NIGISNV 347
                  .||.|.|          |:::..::.             ||::| .|..|: |:....:
Mouse   429 ------FLNMGMGLPSGTLDFFLSVNIPIMEL-------------YGLSECTGLHTVSNLQAYRI 474

  Fly   348 SSAGRPVP--GIKIRIVDEDGKSLGYNQVGEIYVHTGQAWNGYYGNPVETRRMQDFEGWFHTGDL 410
            .|||:.:|  ..|:...::||       :|.:.:.....:.||..:...|.|..|..||.||.||
Mouse   475 LSAGKALPKTHTKVEKENKDG-------IGNLCIWGRHIFMGYLRDKQSTERKVDTHGWLHTNDL 532

  Fly   411 GYFDEQNFLYIVDRKKEILKYNG---LHYWPTEIETVIAELSQVQDVCVVG 458
            |:.|...|||::....:::|.:.   ::.:|.| |.|...:..|:...:||
Mouse   533 GFLDFDKFLYVMGNNNDLIKLSSGEMVNPYPIE-ERVRTRIPIVRYAMLVG 582

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG8834NP_610779.1 CaiC 20..529 CDD:223395 110/563 (20%)
AFD_class_I 46..519 CDD:302604 106/537 (20%)
Acsbg3NP_084417.1 FAA1 74..701 CDD:223953 114/571 (20%)
ACSBG_like 95..700 CDD:213299 108/547 (20%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167839185
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.930

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