DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8834 and slc27a1a

DIOPT Version :9

Sequence 1:	NP_610779.1	Gene:	CG8834 / 36356	FlyBaseID:	FBgn0033733	Length:	535	Species:	Drosophila melanogaster
Sequence 2:	NP_001013555.1	Gene:	slc27a1a / 541410	ZFINID:	ZDB-GENE-050320-112	Length:	647	Species:	Danio rerio

Alignment Length:	559	Identity:	114/559 - (20%)
Similarity:	206/559 - (36%)	Gaps:	113/559 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 AKR--NSIY--------------NYDTSVGKIIFNNMKNWPKNVCQICDVDGVTVTFEQGLTWSI 66
            |||  |.:|              |.:| :..|....:...|.....:.:..|.|.||.|....|.
Zfish    51 AKRDINGLYVLLRVKLALWHYMRNRNT-IPSIFAQTVARHPDKPALVYEATGETWTFSQLDQISN 114

  Fly    67 RIAQYLKKRGLNHKDVIGIAAKNSTYVMPLGVACLMNGTPFHSVNPVLDDATLTHVFSITKPTLI 131
            .:|.:...:|....||:.:..::....:.|.:.....|.....:|..|...:|.|...::....|
Zfish   115 AVAHWALSQGWTSGDVVALFMESRPLQVALWLGLAKVGVEAALINFNLRRDSLLHCVGVSASRGI 179

  Fly   132 FCDGQEYDKVHKATVGWHPEILTLTDHVEGVQGIETL-------LDPTTTEKIYQPE--VLKEGG 187
            ....:..|.|.:.:   |....|:.....|....:.:       |||........|.  .:.:|.
Zfish   180 VFGAELADAVSEVS---HSLSQTMVRFSTGDLKPDLMAALKCQPLDPILASAPRHPPSCTVSKGF 241

  Fly   188 DQTVAILCSSGTTGLPKAVCISNS------------------ILIQDSMLI--TSQSVIYVGSCL 232
            :..:..:.:|||||||||..:.:|                  .:|.|.:.:  ::.:::.||.||
Zfish   242 NDHLFYIYTSGTTGLPKAAIVVHSRYYRIAAFGYLSFRMRPDDIIYDCLPLYHSAGNIMGVGQCL 306

  Fly   233 DWITGLWAFVFSTVFGCTRI----ISNKAFTPEYFVGLVKKYKINYAVLPP--RHLSALITCPDA 291
              |.|| ..|....|..:|.    |.:.....:| :|.:.:|.:...|.|.  :|...|     |
Zfish   307 --IHGL-TVVVKRKFSASRFWEDCIKHNCTVVQY-IGEICRYLLAQPVRPSERQHRVRL-----A 362

  Fly   292 KPDALAPITHLNYGGGSISLATLQRSQELCKTAMFNSGYGMT-----------EVGAITINIGIS 345
            ..:.|.|         |:..|.::|    .:.......||.|           :|||...|   |
Zfish   363 VGNGLRP---------SVWEAFVER----FRVKQIGEFYGATGCNCSIANMDGKVGACGFN---S 411

  Fly   346 NVSSAGRPVPGIKIR------IVDEDGKSLGYNQVGEIYVHTG--------QAWNGYYGNPVETR 396
            .:.....|:..:|:.      :.|:.|..:.. :.||..:..|        :.::||.......:
Zfish   412 RILPNVYPIRLVKVNEETMELVRDKQGLCVSC-RPGEPGLLVGRINQQDPLRRFDGYASQEATRK 475

  Fly   397 RM-----QDFEGWFHTGDLGYFDEQNFLYIVDRKKEILKYNGLHYWPTEIETVIAELSQVQDVCV 456
            ::     :..:..:.:||:...||..::|..||..:..::.|.:...||:|..::.|.:..||.|
Zfish   476 KIAYNVFRKNDSAYLSGDVLVMDELGYMYFRDRSGDTFRWKGENVSTTEVEGTLSGLLRQTDVAV 540

  Fly   457 VGI-YDEREGDAAGALVVKSKGATISAKEIVEHVAKRLP 494
            .|: ....||.|..|.:..|.| :.:....::.|.:.||
Zfish   541 FGVNVPGVEGKAGMAAIADSTG-SFNCNSFLKEVQQALP 578

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8834	NP_610779.1	CaiC	20..529	CDD:223395	112/557 (20%)
CG8834	NP_610779.1	AFD_class_I	46..519	CDD:302604	105/515 (20%)
slc27a1a	NP_001013555.1	PRK08279	75..647	CDD:236217	108/535 (20%)
slc27a1a	NP_001013555.1	AFD_class_I	101..612	CDD:302604	105/508 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583013
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930