DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8834 and acsl1b

DIOPT Version :9

Sequence 1:	NP_610779.1	Gene:	CG8834 / 36356	FlyBaseID:	FBgn0033733	Length:	535	Species:	Drosophila melanogaster
Sequence 2:	NP_001003569.1	Gene:	acsl1b / 445175	ZFINID:	ZDB-GENE-040801-88	Length:	697	Species:	Danio rerio

Alignment Length:	574	Identity:	129/574 - (22%)
Similarity:	212/574 - (36%)	Gaps:	170/574 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    83 IGIAAKNSTYVMPLGVACL---MNGTPFHSVNPVLDDATLTHVFSITKPTLIFCDGQEYDKVHKA 144
            |||.::|........:||.   :...|.:.   .|....::::...|..:.:.||..|     ||
Zfish   150 IGIFSQNRPEWTIAELACYTYSLISVPLYD---TLGTEAISYILDKTCISTVVCDVPE-----KA 206

  Fly   145 TV------GWHPEILTLTDHVE------------GVQGIETLLDPTTTEKIY--QPEVLKEGGDQ 189
            .:      |....:.||....:            |:| |.:|.|.....|.:  |||..:   ..
Zfish   207 GLLLECVSGRQHSVKTLILMADVDADLQSRAQQCGIQ-IISLTDAENMGKTHRRQPEPPQ---PD 267

  Fly   190 TVAILC-SSGTTGLPKA---------------VCISNSI---------------------LIQDS 217
            .:|::| :|||||.||.               :.::||.                     ::|..
Zfish   268 DLAVICFTSGTTGNPKGAMLTHRNIVSNISAFIHVTNSTCPLSSRDSHISYLPLAHMFERVVQGV 332

  Fly   218 MLITSQSVIY----VGSCLDWITGLWAFVFSTVFGCTRIIS-------NKAFTP----------- 260
            :|:....:.|    :...:|.:..|...:|..|   .|:::       .:|.||
Zfish   333 VLLHGARIGYFQGDIRVLMDDLIALKPTIFPVV---PRLLNRMFDKIYGQANTPLKRRLLEFAFR 394

  Fly   261 ----EYFVGLVKKYKINYAVLPPRHLSALITCPDAKPDALAPITHLNYGGGSISLATLQRSQELC 321
                |...|::::..|...::..:..:::..|........|||        |..:.|..|:...|
Zfish   395 RKEAEMKSGIMRRDSIWDKIIFKKVQASVGGCVRMMVTGAAPI--------SEPVLTFLRAALGC 451

  Fly   322 KTAMFNSGYGMTE--VGAITINIGISNVSSAGRPVPGIKIRIVDEDGKSLGY---NQVGEIYVHT 381
            :   |..|||.||  .|:.|...|.......|.|:|...|::||.  ..:.|   |..||:.|..
Zfish   452 Q---FYEGYGQTECTAGSTTTLPGDWTAGHVGAPLPCNDIKLVDV--AEMNYYAANGEGEVCVRG 511

  Fly   382 GQAWNGYYGNPVETRRMQDFEGWFHTGDLGYFDEQNFLYIVDRKKEILKY-NGLHYWPTEIETV- 444
            ..|:.||..:|.:|:...|.|||.||||:|.:.....|.||||||.|.|. .|.:..|.:||.:
Zfish   512 PNAFKGYLKDPEKTKEALDEEGWVHTGDIGRWLPNGSLKIVDRKKHIFKLAQGEYIAPEKIENIY 576

  Fly   445 IAELSQVQ--------DVCVV--------------------GIYDE--REGDAAGAL---VVK-S 475
            |...:.||        ..|:|                    |.|::  :..|...|:   ::| .
Zfish   577 IRSEAVVQAFVHGDSLQACLVAIIVPDPDFLPGWAKKRGIEGTYEDLCKNKDIKKAILEDIIKLG 641

  Fly   476 KGATISAKEIVEHVAKR----------LPATQKQLRAGVQ-----FTDKLPANV 514
            |.:.:.:.|.|:.:|..          |..|.|..||.::     ..|:|.||:
Zfish   642 KESGLKSFEQVKDIALHSEMFTIQNGLLTPTLKAKRADLRNHFRSHIDELYANI 695

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8834	NP_610779.1	CaiC	20..529	CDD:223395	129/574 (22%)
CG8834	NP_610779.1	AFD_class_I	46..519	CDD:302604	129/574 (22%)
acsl1b	NP_001003569.1	PLN02736	88..695	CDD:178337	128/572 (22%)
acsl1b	NP_001003569.1	LC-FACS_euk	116..692	CDD:213293	126/569 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583136
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.930