DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8834 and CG6300

DIOPT Version :9

Sequence 1:	NP_610779.1	Gene:	CG8834 / 36356	FlyBaseID:	FBgn0033733	Length:	535	Species:	Drosophila melanogaster
Sequence 2:	NP_650828.1	Gene:	CG6300 / 42351	FlyBaseID:	FBgn0038730	Length:	537	Species:	Drosophila melanogaster

Alignment Length:	529	Identity:	206/529 - (38%)
Similarity:	326/529 - (61%)	Gaps:	6/529 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 TYNEKDNIWSGAKRNSIYNYDTSVGKIIFNNMKNWPKNVCQICDVDGVTVTFEQGLTWSIRIAQY 71
            :|:....||||......::.|.|:|:|||:.|:..|:...||...:|..:|..:.|..::|:|.|
  Fly     8 SYDNDQKIWSGEPVVKYFDPDLSIGEIIFHEMRRHPQLTAQISATEGTVLTRGELLANAMRLASY 72

  Fly    72 LKKRGLNHKDVIGIAAKNSTYVMPLGVACLMNGTPFHSVNPVLDDATLTHVFSITKPTLIFCDGQ 136
            ::..||...|::||..:|:|:::.:..||..||..|||:|...|..|:..::.:|:|::|||||.
  Fly    73 MRSLGLLQSDIVGIIGRNTTHMLAVAYACFFNGIAFHSLNITYDRDTIEKIYKVTRPSIIFCDGD 137

  Fly   137 EYDKVHKATVGWHPEILTLTDH-VEGVQGIETLLDPTTTEKIYQPEVLKEGGDQTVAILCSSGTT 200
            |::||..||.....:|:|:.:| ::.::..|.:..|  .|:.:||..|::|.|||:|||||||||
  Fly   138 EFEKVRSATAELDVKIVTMRNHPLDSIKIDEVVATP--IEENFQPAKLEKGNDQTLAILCSSGTT 200

  Fly   201 GLPKAVCISNS-ILIQDSMLITSQSVIYVGSCLDWITGLWAFVFSTVFGCTRIISNKAFTPEYFV 264
            |.||||.|:|| .::..:..:|:..|.|..:.|||||||...:.|.||..||||::.||.|.:.:
  Fly   201 GTPKAVTITNSRHILAGNYHLTTADVQYSHNTLDWITGLLTTITSGVFSTTRIIADNAFDPAFAL 265

  Fly   265 GLVKKYKINYAVLPPRHLSALITCPDAKPDALAPITHLNYGGGSISLATLQRSQELCKTAMFNSG 329
            .::::||:.:.:.||..::.:|.|||.:...::.:....:||...:|...:..:...........
  Fly   266 RIIEEYKVTWTIQPPSSMALMINCPDFETCDMSSLRCYMFGGSRAALEVQKGIRSRLSHDCLQFV 330

  Fly   330 YGMTEVGAI-TINIGI-SNVSSAGRPVPGIKIRIVDEDGKSLGYNQVGEIYVHTGQAWNGYYGNP 392
            ||.||:||: |||... ....|.|:.|.|:|::|:::||:|||.:::||:.:...|.|:|||||.
  Fly   331 YGFTELGAMATINCHFDEKTGSVGQLVNGLKMKIINDDGESLGPDEIGEVCIMNNQHWSGYYGNE 395

  Fly   393 VETRRMQDFEGWFHTGDLGYFDEQNFLYIVDRKKEILKYNGLHYWPTEIETVIAELSQVQDVCVV 457
            ||||.|:|..||:|:|||||.|...||||:|||||:|||..:.|:|.:||:||:|:.||.:|||.
  Fly   396 VETRNMRDSLGWYHSGDLGYMDRDGFLYIMDRKKEMLKYQNIMYYPNDIESVISEMPQVAEVCVF 460

  Fly   458 GIYDEREGDAAGALVVKSKGATISAKEIVEHVAKRLPATQKQLRAGVQFTDKLPANVNGKTMRKT 522
            ||:....||.|.|.|||..|:.:.|:::|::|..|..:..|||..|....|.|..:.||||.|..
  Fly   461 GIWSNIFGDEAAAAVVKKLGSELEAQDVVDYVRSRTDSKYKQLNGGAVIVDDLQRSANGKTNRMA 525

  Fly   523 ARDVFVALR 531
            .:..|:.|:
  Fly   526 NKAYFLHLK 534

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8834	NP_610779.1	CaiC	20..529	CDD:223395	200/512 (39%)
CG8834	NP_610779.1	AFD_class_I	46..519	CDD:302604	189/476 (40%)
CG6300	NP_650828.1	CaiC	26..523	CDD:223395	198/498 (40%)
CG6300	NP_650828.1	AFD_class_I	47..522	CDD:302604	189/476 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471323
Domainoid	1	1.000	215	1.000	Domainoid score	I5876
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG26958
OrthoDB	1	1.010	-	-		D24284at7147
OrthoFinder	1	1.000	-	-		FOG0004528
OrthoInspector	1	1.000	-	-		mtm9651
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24096
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X778
	9	8.960