Protein Alignment CG8834 and SLC27A1

DIOPT Version :9

• Sequence 1: NP_610779.1
• Gene: CG8834 / 36356
• FlyBaseID: FBgn0033733
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: XP_011526302.1
• Gene: SLC27A1 / 376497
• HGNCID: 10995
• Length: 658
• Species: Homo sapiens
• Alignment Length: 553
• Identity: 117/553 - (21%)
• Similarity: 194/553 - (35%)
• Gaps: 155/553 - (28%)

  Fly    42 PKNVCQICDVDGVTVTFEQGLTWSIRIAQYLKKRGLNHKDVIGIAAKNSTYVMPLGVACLMNGTP 106
            |:.:..:....|...||.|...:|..:|...::.|....||:.|..:.....:.|.:.....|.
Human    90 PERLALVDAGTGECWTFAQLDAYSNAVANLFRQLGFAPGDVVAIFLEGRPEFVGLWLGLAKAGM- 153

  Fly   107 FHSVNPVLDDATLTHVFSITKPTLIFCDGQEYDK---------VHKATVGWH--PEILTLTDHVE 160
                     :|.|.:| ::.:..|.||.|....|         ...|.|..|  ..::.......
Human   154 ---------EAALLNV-NLRREPLAFCLGTSGAKALIFGGEMVAAVAEVSGHLGKSLIKFCSGDL 208

  Fly   161 GVQGI--ET-LLDPTTTEKIYQP--EVLKEGGDQTVAILCSSGTTGLPKAVCISNS--------- 211
            |.:||  :| ||||...|....|  ::..:|.|..:..:.:|||||||||..:.:|
Human   209 GPEGILPDTHLLDPLLKEASTAPLAQIPSKGMDDRLFYIYTSGTTGLPKAAIVVHSRYYRMAAFG 273

  Fly   212 ---------ILIQDSMLI--TSQSVIYVGSCLDWITGLWAFVFSTVFGCTRIISNKAFTPEYFVG 265
                     .::.|.:.:  ::.::|.||.||             ::|.| ::..|.|:...|..
Human   274 HHAYRMQAADVLYDCLPLYHSAGNIIGVGQCL-------------IYGLT-VVLRKKFSASRFWD 324

  Fly   266 LVKKYKINYAVLPPRHLSALITCPDAKPDALAPITHLNYGGGSISLATLQRSQELCKTAM----- 325
            ...||  |..:...||...|  |                       ..:|...|:|:..:
Human   325 DCIKY--NCTINGVRHCRLL--C-----------------------LVVQYIGEICRYLLKQPVR 362

  Fly   326 -----------------------FNSGYGMTEV----GAITINIGISN----VSSAG---RPVPG 356
                                   |...:|:.::    ||...|..|:|    |.|.|   |.:|.
Human   363 EAERRHRVRLAVGNGLRPAIWEEFTERFGVRQIGEFYGATECNCSIANMDGKVGSCGFNSRILPH 427

  Fly   357 I-KIRI--VDEDGKSLGYN--------QVGEIYVHTGQ--------AWNGYYGNPVETRRMQDFE 402
            : .||:  |:||...|..:        |.||..:..||        .::||......::::.  .
Human   428 VYPIRLVKVNEDTMELLRDAQGLCIPCQAGEPGLLVGQINQQDPLRRFDGYVSESATSKKIA--H 490

  Fly   403 GWFHTGDLGY-------FDEQNFLYIVDRKKEILKYNGLHYWPTEIETVIAELSQVQDVCVVGIY 460
            ..|..||..|       .||..::|..||..:..::.|.:...||:|.|::.|....||.|.|:.
Human   491 SVFSKGDSAYLSGDVLVMDELGYMYFRDRSGDTFRWRGENVSTTEVEGVLSRLLGQTDVAVYGVA 555

  Fly   461 DEREGDAAGALVVKSKGATISAKEIVEHVAKRL 493
            .......||...|....:.:....|.:.:.|.|
Human   556 VPGVEGKAGMAAVADPHSLLDPNAIYQELQKVL 588

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8834	NP_610779.1	CaiC	20..529	CDD:223395	117/553 (21%)
		AFD_class_I	46..519	CDD:302604	116/549 (21%)
SLC27A1	XP_011526302.1	PRK08279	42..656	CDD:236217	117/553 (21%)
		metallo-hydrolase-like_MBL-fold	64..>135	CDD:304873	11/44 (25%)
		AFD_class_I	101..623	CDD:302604	116/542 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149016
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930