Protein Alignment CG8834 and ACSL4

DIOPT Version :10

• Sequence 1: NP_610779.1
• Gene: CG8834 / 36356
• FlyBaseID: FBgn0033733
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_075266.1
• Gene: ACSL4 / 2182
• HGNCID: 3571
• Length: 711
• Species: Homo sapiens
• Alignment Length: 587
• Identity: 118/587 - (20%)
• Similarity: 202/587 - (34%)
• Gaps: 157/587 - (26%)

  Fly     8 YNEKDNIWSG---AKRNSIYNYDTSVGKIIFNNMKNWPKNVCQICDVDGVTVTFEQGLTWSIRIA 69
            :.:||::.:.   ::.|.:........|:|..|.| |    ....:|:.....|..|||
Human    90 FGKKDSLGTREILSEENEMQPNGKVFKKLILGNYK-W----MNYLEVNRRVNNFGSGLT------ 143

  Fly    70 QYLKKRGLNHKDVIGIAAKNSTYVMPLGVACLMNGTPF-------------HSVN---------- 111
                ..||..|:.|.|..:.....|.....|.....|.             |.:|
Human   144 ----ALGLKPKNTIAIFCETRAEWMIAAQTCFKYNFPLVTLYATLGKEAVVHGLNESEASYLITS 204

  Fly   112 ----------PVLDDATLTHVFSITKPTLIFCDGQEYDKVHKATVGWHPEILTLTDHVEGVQGIE 166
                      .:||.:.:.|:        |:.|.:..:|..      :||..    .:..:|.:|
Human   205 VELLESKLKTALLDISCVKHI--------IYVDNKAINKAE------YPEGF----EIHSMQSVE 251

  Fly   167 TLLDPTTTEKIYQPEVLKEGGDQTVAILCSSGTTGLPKAVCISNSILIQDSMLITSQ-------- 223
            .|  .:..|.:..|.......|..: ::.:||:||.||.|.:.:|.||..   :|.|
Human   252 EL--GSNPENLGIPPSRPTPSDMAI-VMYTSGSTGRPKGVMMHHSNLIAG---MTGQCERIPGLG 310

  Fly   224 -SVIYVGSC-LDWITGLWAFVFSTVFGCTRIISNKAFTPEYFVGLVKKYKINYAVLPPRHLSALI 286
             ...|:|.. |..:..|.|.:....:||....|:.....:....:.|..|.:..||.|..::|:.
Human   311 PKDTYIGYLPLAHVLELTAEISCFTYGCRIGYSSPLTLSDQSSKIKKGSKGDCTVLKPTLMAAVP 375

  Fly   287 TCPD-AKPDALAPITHLNY---------------------------------------------- 304
            ...| ...:.::.:..:||
Human   376 EIMDRIYKNVMSKVQEMNYIQKTLFKIGYDYKLEQIKKGYDAPLCNLLLFKKVKALLGGNVRMML 440

  Fly   305 -GGGSISLATLQRSQELCKTAMFNSGYGMTE-VGAITI-NIGISNVSSAGRPVPGIKIRIVD-ED 365
             ||..:|..| .|...:|.......|||:|| .||.|: .:........|.|:...:|::.| ::
Human   441 SGGAPLSPQT-HRFMNVCFCCPIGQGYGLTESCGAGTVTEVTDYTTGRVGAPLICCEIKLKDWQE 504

  Fly   366 GKSLGY------NQVGEIYVHTGQAWNGYYGNPVETRRMQDF------EGWFHTGDLGYFDEQNF 418
            |   ||      |..|||.:.......||:.|  |.:..:|:      :.||.|||:|.|.....
Human   505 G---GYTINDKPNPRGEIVIGGQNISMGYFKN--EEKTAEDYSVDENGQRWFCTGDIGEFHPDGC 564

  Fly   419 LYIVDRKKEILKYNGLHYWPT-EIETVIAELSQVQDVCVVGIYDEREGDAAGALVVKSKGATISA 482
            |.|:||||:::|.....|... ::|..:.....:.::|.....|  :......:|...|..|:.|
Human   565 LQIIDRKKDLVKLQAGEYVSLGKVEAALKNCPLIDNICAFAKSD--QSYVISFVVPNQKRLTLLA 627

  Fly   483 KE 484
            ::
Human   628 QQ 629

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8834	NP_610779.1	Firefly_Luc_like	46..519	CDD:341237	110/546 (20%)
ACSL4	NP_075266.1	LC_FACS_euk1	121..696	CDD:341294	113/556 (20%)