Protein Alignment CG8834 and ACSL4

DIOPT Version :9

• Sequence 1: NP_610779.1
• Gene: CG8834 / 36356
• FlyBaseID: FBgn0033733
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: XP_024308119.1
• Gene: ACSL4 / 2182
• HGNCID: 3571
• Length: 717
• Species: Homo sapiens
• Alignment Length: 588
• Identity: 117/588 - (19%)
• Similarity: 201/588 - (34%)
• Gaps: 159/588 - (27%)

  Fly     8 YNEKDNIWSG---AKRNSIYNYDTSVGKIIFNNMKNWPKNVCQICDVDGVTVTFEQGLTWSIRIA 69
            :.:||::.:.   ::.|.:........|:|..|.| |    ....:|:.....|..|||
Human    96 FGKKDSLGTREILSEENEMQPNGKVFKKLILGNYK-W----MNYLEVNRRVNNFGSGLT------ 149

  Fly    70 QYLKKRGLNHKDVIGIAAKNSTYVMPLGVACLMNGTPF-------------HSVN---------- 111
                ..||..|:.|.|..:.....|.....|.....|.             |.:|
Human   150 ----ALGLKPKNTIAIFCETRAEWMIAAQTCFKYNFPLVTLYATLGKEAVVHGLNESEASYLITS 210

  Fly   112 ----------PVLDDATLTHVFSITKPTLIFCDGQEYDKVHKATVGWHPEILTLTDHVEGVQGIE 166
                      .:||.:.:.|:        |:.|.:..:|..      :||..    .:..:|.:|
Human   211 VELLESKLKTALLDISCVKHI--------IYVDNKAINKAE------YPEGF----EIHSMQSVE 257

  Fly   167 TLLDPTTTEKIYQPEVLKEGGDQTVAILCSSGTTGLPKAVCISNSILIQDSMLITSQ-------- 223
            .|  .:..|.:..|.......|..: ::.:||:||.||.|.:.:|.||..   :|.|
Human   258 EL--GSNPENLGIPPSRPTPSDMAI-VMYTSGSTGRPKGVMMHHSNLIAG---MTGQCERIPGLG 316

  Fly   224 -SVIYVGSC-LDWITGLWAFVFSTVFGCTRIISNKAFTPEYFVGLVKKYKINYAVLPPRHLSALI 286
             ...|:|.. |..:..|.|.:....:||....|:.....:....:.|..|.:..||.|..::|:.
Human   317 PKDTYIGYLPLAHVLELTAEISCFTYGCRIGYSSPLTLSDQSSKIKKGSKGDCTVLKPTLMAAVP 381

  Fly   287 TCPD-AKPDALAPITHLNY---------------------------------------------- 304
            ...| ...:.::.:..:||
Human   382 EIMDRIYKNVMSKVQEMNYIQKTLFKIGYDYKLEQIKKGYDAPLCNLLLFKKVKALLGGNVRMML 446

  Fly   305 -GGGSISLATLQRSQELCKTAMFNSGYGMTE---VGAITINIGISNVSSAGRPVPGIKIRIVD-E 364
             ||..:|..| .|...:|.......|||:||   .|.:| .:........|.|:...:|::.| :
Human   447 SGGAPLSPQT-HRFMNVCFCCPIGQGYGLTESCGAGTVT-EVTDYTTGRVGAPLICCEIKLKDWQ 509

  Fly   365 DGKSLGY------NQVGEIYVHTGQAWNGYYGNPVETRRMQDF------EGWFHTGDLGYFDEQN 417
            :|   ||      |..|||.:.......||:.|  |.:..:|:      :.||.|||:|.|....
Human   510 EG---GYTINDKPNPRGEIVIGGQNISMGYFKN--EEKTAEDYSVDENGQRWFCTGDIGEFHPDG 569

  Fly   418 FLYIVDRKKEILKYNGLHYWPT-EIETVIAELSQVQDVCVVGIYDEREGDAAGALVVKSKGATIS 481
            .|.|:||||:::|.....|... ::|..:.....:.::|.....|  :......:|...|..|:.
Human   570 CLQIIDRKKDLVKLQAGEYVSLGKVEAALKNCPLIDNICAFAKSD--QSYVISFVVPNQKRLTLL 632

  Fly   482 AKE 484
            |::
Human   633 AQQ 635

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8834	NP_610779.1	CaiC	20..529	CDD:223395	115/573 (20%)
		AFD_class_I	46..519	CDD:302604	109/547 (20%)
ACSL4	XP_024308119.1	LC-FACS_euk	127..714	CDD:213293	112/557 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165148972
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930