Protein Alignment CG8834 and ACSL1

DIOPT Version :10

• Sequence 1: NP_610779.1
• Gene: CG8834 / 36356
• FlyBaseID: FBgn0033733
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_001986.2
• Gene: ACSL1 / 2180
• HGNCID: 3569
• Length: 698
• Species: Homo sapiens
• Alignment Length: 545
• Identity: 112/545 - (20%)
• Similarity: 185/545 - (33%)
• Gaps: 134/545 - (24%)

  Fly     8 YNEKDNIWSGAKRN-SIYNYDTSVGKIIFNNMKNWPKNVCQICDVDGVTVTFEQGLTWSIRIAQY 71
            |::...::.|.:|. .:.|....:|....:....|              ::::|....|..|...
Human    86 YDDVTTLYEGFQRGIQVSNNGPCLGSRKPDQPYEW--------------LSYKQVAELSECIGSA 136

  Fly    72 LKKRGLN--HKDVIGIAAKNSTYVMPLGVACLMNGTPFHSVNPVLDDATLTHVFSITKPTLIFCD 134
            |.::|..  ....|||.|:|....:.:...|.........:...|.:..:|::.:..:.:|:|.|
Human   137 LIQKGFKTAPDQFIGIFAQNRPEWVIIEQGCFAYSMVIVPLYDTLGNEAITYIVNKAELSLVFVD 201

  Fly   135 GQEYDKVHKATVGWHPEILTLTDHVEGVQGIETLLDP----TTTEKIYQPEVLKEG--------- 186
            ..|..|:.                   ::|:|..|.|    ......|..|:::.|
Human   202 KPEKAKLL-------------------LEGVENKLIPGLKIIVVMDAYGSELVERGQRCGVEVTS 247

  Fly   187 ------------------GDQTVAILC-SSGTTGLPKAVCISNSILIQDSMLITSQSVIYVGSCL 232
                              ..:.:|::| :|||||.||...:::..::.|.......:...|..|.
Human   248 MKAMEDLGRANRRKPKPPAPEDLAVICFTSGTTGNPKGAMVTHRNIVSDCSAFVKATENTVNPCP 312

  Fly   233 D--WITGL-WAFVFSTVFGCTRIISNKAFTPEYFVGLVKKYKINYAVLP-------PRHLSA--- 284
            |  .|:.| .|.:|..|..|..:......  .:|.|.::....:..||.       ||.|:.
Human   313 DDTLISFLPLAHMFERVVECVMLCHGAKI--GFFQGDIRLLMDDLKVLQPTVFPVVPRLLNRMFD 375

  Fly   285 -------------LITCPDAKPDALAPITHLNYG--------------------GGSISL----- 311
                         |:.....:.:|     .|..|                    ||.:.|
Human   376 RIFGQANTTLKRWLLDFASKRKEA-----ELRSGIIRNNSLWDRLIFHKVQSSLGGRVRLMVTGA 435

  Fly   312 ----ATLQRSQELCKTAMFNSGYGMTE--VGAITINIGISNVSSAGRPVPGIKIRIVD-EDGKSL 369
                ||:...........|..|||.||  .|......|.......|.|:|...|::|| |:...:
Human   436 APVSATVLTFLRAALGCQFYEGYGQTECTAGCCLTMPGDWTAGHVGAPMPCNLIKLVDVEEMNYM 500

  Fly   370 GYNQVGEIYVHTGQAWNGYYGNPVETRRMQDFEGWFHTGDLGYFDEQNFLYIVDRKKEILKY-NG 433
            .....||:.|.....:.||..:|.:|....|.:||.||||:|.:.....|.|:||||.|.|. .|
Human   501 AAEGEGEVCVKGPNVFQGYLKDPAKTAEALDKDGWLHTGDIGKWLPNGTLKIIDRKKHIFKLAQG 565

  Fly   434 LHYWPTEIETVIAELSQVQDVCVVG 458
            .:..|.:||.:......|..|.|.|
Human   566 EYIAPEKIENIYMRSEPVAQVFVHG 590

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8834	NP_610779.1	Firefly_Luc_like	46..519	CDD:341237	106/506 (21%)
ACSL1	NP_001986.2	LC-FACS_euk	116..694	CDD:341250	107/515 (21%)