Protein Alignment CG8834 and ACSF3

DIOPT Version :9

• Sequence 1: NP_610779.1
• Gene: CG8834 / 36356
• FlyBaseID: FBgn0033733
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: XP_005256350.1
• Gene: ACSF3 / 197322
• HGNCID: 27288
• Length: 610
• Species: Homo sapiens
• Alignment Length: 559
• Identity: 129/559 - (23%)
• Similarity: 224/559 - (40%)
• Gaps: 124/559 - (22%)

  Fly    57 TFEQGLTWSIRIAQYLKK------RGLNHKDVIGIAAKNSTYVMPLGVACLMNG--TPFHSVNPV 113
            |:.:..:.|:|::|.:.:      ..|..:.|..:.|.:::||:....:.:..|  .|.:..:|.
Human    67 TYRELYSRSLRLSQEICRLCGCVGGDLREERVSFLCANDASYVVAQWASWMSGGVAVPLYRKHPA 131

  Fly   114 LDDATLTHVFSITKPTLIFCDGQEYDKVHKATVGWHPEILTLTDHVEGVQGIETL-LDPTT-TEK 176
               |.|.:|         .||.|      .:.|....|.|.|...|....|:..| |.|.. |..
Human   132 ---AQLEYV---------ICDSQ------SSVVLASQEYLELLSPVVRKLGVPLLPLTPAIYTGA 178

  Fly   177 IYQP-EV-LKEGG--DQTVAILCSSGTTGLPKAVCISNSILIQDSMLITSQSVIYVGSCLDWITG 237
            :.:| || :.|.|  ::...|:.:|||||.||.|            |.|.|::..|      :||
Human   179 VEEPAEVPVPEQGWRNKGAMIIYTSGTTGRPKGV------------LSTHQNIRAV------VTG 225

  Fly   238 L---WAFVFSTVF----------------------GCTRIISNKAFTPEYFVGLVKKY------K 271
            |   ||:....|.                      |.|.::..: |:|:.   :.:|:      :
Human   226 LVHKWAWTKDDVILHVLPLHHVHGVVNALLCPLWVGATCVMMPE-FSPQQ---VWEKFLSSETPR 286

  Fly   272 INYAVLPPRHLSALI-------TCPDAKPDALAPITH-----LNYGGGSISLATLQRSQELCKTA 324
            ||..:..|...:.|:       |.|.|: |.|..:..     :..|..::.|..|::.:.:....
Human   287 INVFMAVPTIYTKLMEYYDRHFTQPHAQ-DFLRAVCEEKIRLMVSGSAALPLPVLEKWKNITGHT 350

  Fly   325 MFNSGYGMTEVG-AIT--INIGISNVSSAGRPVPGIKIRIV-----------------DEDGKSL 369
            :... |||||:| |::  :...:....|.|.|:||:::|||                 ||.|..:
Human   351 LLER-YGMTEIGMALSGPLTTAVRLPGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERGTKV 414

  Fly   370 --GYNQ-VGEIYVHTGQAWNGYYGNPVETRRMQDFEGWFHTGDLGYFDEQNFLYIVDRKKEILKY 431
              |:.: .||:.|.....:..|:..|.||:.....:|||.|||...|.:..:........:|:|.
Human   415 TPGFEEKEGELLVRGPSVFREYWNKPEETKSAFTLDGWFKTGDTVVFKDGQYWIRGRTSVDIIKT 479

  Fly   432 NGLHYWPTEIETVIAELSQVQDVCVVGIYDEREGDAAGALVVKSKGATISAKEIVEHVAKRLPAT 496
            .|......|:|..:.....:.||.|:|:.|...|....|:|...:|.::|.:|:.|....:...|
Human   480 GGYKVSALEVEWHLLAHPSITDVAVIGVPDMTWGQRVTAVVTLREGHSLSHRELKEWARLKEHPT 544

  Fly   497 QKQLRAGVQFTDK--LPANVNGKTMRKTARDVFVALRVS 533
            :::..:.:....|  |.:.:...|.|..||...|:..||
Human   545 KRRENSILNIGRKRNLASGMRALTGRMAARRAAVSSEVS 583

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8834	NP_610779.1	CaiC	20..529	CDD:223395	126/553 (23%)
		AFD_class_I	46..519	CDD:302604	122/543 (22%)
ACSF3	XP_005256350.1	MCS	55..546	CDD:341264	120/520 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910