Protein Alignment CG8834 and mec-18

DIOPT Version :9

• Sequence 1: NP_610779.1
• Gene: CG8834 / 36356
• FlyBaseID: FBgn0033733
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_508731.3
• Gene: mec-18 / 180701
• WormBaseID: WBGene00003179
• Length: 638
• Species: Caenorhabditis elegans
• Alignment Length: 614
• Identity: 145/614 - (23%)
• Similarity: 248/614 - (40%)
• Gaps: 122/614 - (19%)

  Fly    15 WSGAKRNSIYNYDTSVGKIIFNNMKNWPKNVCQICDVD-GVTVTFEQGLTWSIRIAQYLKKRGLN 78
            |......|.::|       .|:.:.....|:. |.||| |....:.:...|....|..||:..:.
 Worm    11 WDKTAAQSFHDY-------FFSKISAHGSNLA-IVDVDSGKQWRYSEIRNWCEMCATRLKELQVT 67

  Fly    79 HKDVIGIAAKNSTYVMPLGVACLMNGTPFHSVN---------PVLDDATLTHVF----------- 123
            ....:.:....:...:.:.:||.:.|....:||         .::|.:..||:.
 Worm    68 SGSRVAVITGTTGQAIFVHLACSIIGCSAVAVNGWNAVDEIWTLVDLSEATHLIVENQFMQKADD 132

  Fly   124 ------------------------------------SI---TKPTLIFCDGQEYDKVHKATVGWH 149
                                                ||   .||.|:       .::..|.:...
 Worm   133 VRRKAQMRGGGRIKHVRQIEDVLTAERINVDSARKRSIDVKQKPPLV-------KEMSLAKINLT 190

  Fly   150 P----EILTLTDHVEGVQGIETLLDPTTTEKIYQPE-----VLKEGGDQTVAILCSSGTTGLPKA 205
            |    :|..||..|..|.|....|:......:...|     :.:..|...:.||.:||||||.||
 Worm   191 PVLPEDIADLTSPVSEVSGQSKELNGDVESSVVDSEEVQTPIQQVSGQNPLLILFTSGTTGLAKA 255

  Fly   206 VCISNSILIQDSMLIT--------SQSVIYVGSCLDWITGLWAFVFSTVFGCTRIISNKAFTPEY 262
            ..:|:..||.:...|:        ::....:...:..|.|:.:..::.:.|.:..:.:|.....:
 Worm   256 AELSHRSLIINIQQISLPLYGPVQTKERFLLPLSIAHIYGIVSAYYALINGASLYLISKQSNRLF 320

  Fly   263 FVGLVKKYKINYAVLPPRHLSALITCPDAKPD------------ALAPITHLNYGGGSISLATLQ 315
            ...||.. :||...:.|..:..:.|  ||..|            |.|||       .|.|.|.::
 Worm   321 METLVNN-QINVMHITPAIVHWMAT--DAIVDDYKTPNLRSVLCAGAPI-------DSNSAAAMK 375

  Fly   316 RSQELCKTAMFNSGYGMTEVGAI-TINIGI-SNVSSAGRPVPGIKIRIVDEDGKSLGY-NQVGEI 377
            ....:   ..|...:||||:|.| |::..: ..:.|.|.|:||:..::|:.:.|.|.. .|.|:|
 Worm   376 SRLNI---KDFRQSFGMTELGGICTMSPYLDEKIESVGNPLPGMLFKVVNWETKQLCLPRQPGQI 437

  Fly   378 YVHTGQAWNGYYGNPVETRRMQDFEGWFHTGDLGYFDEQNFLYIVDRKKEILKYNGLHYWPTEIE 442
            .|...|....||.||..|..:.|..|:..|||.|::||...:|::||.|:|:|..|....|:|:|
 Worm   438 IVLGPQVSPCYYKNPKATSELFDATGFVKTGDAGFYDEVGRIYVLDRIKDIIKCKGTMICPSEVE 502

  Fly   443 TVIAELSQVQDVCVVGIYDEREGDAAGALVVK-SKGATISAKEIVEHVAKRLPATQKQLRAGVQF 506
            .|:...:.:.|..|||..|...|:...|.||| ::...:::.|:.::|:.:: ||.|:||.||.|
 Worm   503 LVLRAHAGIDDCAVVGRQDHVTGEVPAAFVVKNAQHPLLASAEVRQYVSGKI-ATFKELRGGVFF 566

  Fly   507 TDKLPANVNGKTMRKTARDVFVALRVSGK 535
            ..::|.:|.||.:|:..|..:...|.:.|
 Worm   567 ISEIPRSVCGKILRRNLRQFWDRERTNSK 595

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8834	NP_610779.1	CaiC	20..529	CDD:223395	142/601 (24%)
		AFD_class_I	46..519	CDD:302604	136/565 (24%)
mec-18	NP_508731.3	CaiC	12..585	CDD:223395	141/601 (23%)
		AFD_class_I	35..579	CDD:302604	136/565 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24096
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010