DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8834 and acs-14

DIOPT Version :9

Sequence 1:	NP_610779.1	Gene:	CG8834 / 36356	FlyBaseID:	FBgn0033733	Length:	535	Species:	Drosophila melanogaster
Sequence 2:	NP_505451.1	Gene:	acs-14 / 179330	WormBaseID:	WBGene00008669	Length:	544	Species:	Caenorhabditis elegans

Alignment Length:	537	Identity:	140/537 - (26%)
Similarity:	225/537 - (41%)	Gaps:	76/537 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 KIIFNNMKNWPKNVCQICDVDGVTVTFEQGLTWSIRIAQYLKKRGLNHKDVIGIAAKNSTYVMPL 96
            ||.|.:..| ||:.          :||||....:..:|.||...|.. |||..:...|..:....
Worm    35 KIAFVSGDN-PKHF----------ITFEQLRKDAFAVAMYLHSIGFK-KDVAAVVLPNVWHYTSF 87

  Fly    97 GVACLMNGTPFHSVNPVLDDATLTHVFSITKPTLIFCDGQEYDKVHKATVGWHPEILTLTDHVEG 161
            .:.|.:||......:.:..|..|...|..::..::|    .|:       .:.|::|........
Worm    88 FIGCAINGGAVSGASALFTDYELQRQFVDSRAKVVF----TYE-------DFLPKVLLAVKQSPN 141

  Fly   162 VQGIETLLDP---------------TTTEKIYQPEVLKEGGDQTVAILCSSGTTGLPKAVCISNS 211
            :|.|..:..|               .:|.....|:|..:..:..:.:..||||||.||.|.:|:
Worm   142 IQKIIVIPKPVGSSLPAGVVSWNEVVSTPVTALPQVPIDVHNDLLVLPYSSGTTGPPKGVMLSH- 205

  Fly   212 ILIQDSMLITSQSVIYVGSCLDWITGLW------AFVFSTVF--------------GCTRIISNK 256
              ...:.:|:....|.....||.:...|      |.:|...:              |.|.|:.:.
Worm   206 --YNFTSMISMYLAIDKSHILDVLDPNWDCYNEKALLFLPFYHVYGFGLLNHCLLKGMTGIVMSH 268

  Fly   257 AFTPEYFVGLVKKYKINYAVLPPRHLSALITCPDAKPDALAPITHLNYG---GGSISLATLQRSQ 318
             |.|..|:..|:.||:....|.|..:..|...|......|:.:..:..|   .|...:..|:|..
Worm   269 -FEPNNFLTAVQNYKVRCLCLVPPIMVFLAKHPICDKFDLSSVQMIMAGAAPAGKDLIEELKRKY 332

  Fly   319 ELCKTAMFNSGYGMTEVGAITINIGISN---VSSAGRPVPGIKIRIVDEDG--KSLGYNQVGEIY 378
            ...|  ....||||||....:....:.|   ..|.|:....:.::|| |.|  :....||.|||.
Worm   333 TNLK--YIQQGYGMTECSMASHLPDLRNDQPYGSVGKLASNLVMKIV-EPGTDREQPVNQRGEIC 394

  Fly   379 VHTGQAWNGYYGNPVETRRMQDFEGWFHTGDLGYFDEQNFLYIVDRKKEILKYNGLHYWPTEIET 443
            |.......||.|.| |.......:||.||||:||.:|...|:||||.||::|..||...|.|:|.
Worm   395 VRGPTIMLGYLGRP-EATASTVIDGWLHTGDIGYLNEDGNLFIVDRLKELIKVKGLQVPPAELED 458

  Fly   444 VIAELSQVQDVCVVGIYDEREGDAAGALVVKSKGATISAKEIVEHVAKRLPATQKQLRAGVQFTD 508
            ::....:::|..|:||.|.:.|:...|.||::.. |::.:|:.:.|..:: :..|||..||:|.:
Worm   459 LLLSHPKIRDCAVIGIPDAKAGELPKAFVVRADN-TLTEQEVKDFVKPKV-SPYKQLEGGVEFIE 521

  Fly   509 KLPANVNGKTMRKTARD 525
            ::|.:..||.:|:..||
Worm   522 EIPKSAAGKILRRFLRD 538

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8834	NP_610779.1	CaiC	20..529	CDD:223395	140/537 (26%)
CG8834	NP_610779.1	AFD_class_I	46..519	CDD:302604	131/515 (25%)
acs-14	NP_505451.1	CaiC	12..539	CDD:223395	140/537 (26%)
acs-14	NP_505451.1	Firefly_Luc_like	37..532	CDD:213279	135/527 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24096
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.010