DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8834 and acs-7

DIOPT Version :9

Sequence 1:	NP_610779.1	Gene:	CG8834 / 36356	FlyBaseID:	FBgn0033733	Length:	535	Species:	Drosophila melanogaster
Sequence 2:	NP_495979.1	Gene:	acs-7 / 174472	WormBaseID:	WBGene00007228	Length:	540	Species:	Caenorhabditis elegans

Alignment Length:	547	Identity:	134/547 - (24%)
Similarity:	248/547 - (45%)	Gaps:	66/547 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 NYDTSVGKIIFNNMK----NWPKNVCQI-CDVDGVTVTFEQGLTWSIRIAQYLKKRGLNHKDVIG 84
            |:|..|.:::....|    ..|.||..: .:.:..::.|:|.....::|:::..:.|....||..
Worm    10 NHDKPVHEVLLERFKVHQEKDPDNVAFVTAENEDDSLGFQQLGKKVLQISEWFVENGYKKGDVFL 74

  Fly    85 IAAKNS--TYVMPLGV--------ACLMNGTPFHSVNPVLDDATLTHVFSITKPTLIF----CDG 135
            :|:.|:  .:...||.        |.....|.| .:|..::|:. :.|..:.|.||..    |..
Worm    75 LASYNNWRCFAAALGAWRAGLIVSAAASQFTSF-EMNYQIEDSQ-SQVILVDKHTLPVVQEACKN 137

  Fly   136 QEYDKVHKATVGWHP-----EILTLTDHVEGVQGIE-TLLDPTTTEKIYQPEVLKEGGDQTVAIL 194
            .::.| ...::..:|     :...||..:  |:.:: .|:||.               :..|.:.
Worm   138 LKFVK-QIISISANPPSPVIKFDVLTSRL--VRNLKMPLIDPK---------------NDIVFLP 184

  Fly   195 CSSGTTGLPKAVCISN---SILIQDSMLITSQSVIYVGSCLDWI-------------TGLWAFVF 243
            .||||||.||.|.||:   |::::.|:.....:...:|...|::             .|::..:.
Worm   185 YSSGTTGKPKGVMISHLNFSMMLESSLRFFDANAKAIGLPPDFVLPYDLHFLPMYHAMGMFRTLL 249

  Fly   244 STVFGCTRIISNKAFTPEYFVGLVKKYKINYAVLPPRHLSALITCPDAKPDALAPITHLNYGGGS 308
            ::..|.|:|:..| |..|..:..::||.|....|.|.....::..|..:...::.:..:..|...
Worm   250 TSYRGTTQIMFTK-FDMELMLKNIEKYSIMVLSLVPAIAVRMLNSPLLQKYDVSSLVSVTVGSAP 313

  Fly   309 ISLATLQRSQELCKTAMFNSGYGMTEVGAIT-INIGISNVSSAGRPVPGIKIRIVDEDGKSLGYN 372
            ...:..::.::|........||||||:...| :....|...|.||.|||..:::..|||...|.:
Worm   314 FPESASKKLKQLLPNVNIVQGYGMTELTFATHLQSPGSPDGSVGRLVPGTSMKVKKEDGTLCGPH 378

  Fly   373 QVGEIYVHTGQAWNGYYGNPVETRRMQDFEGWFHTGDLGYFDEQNFLYIVDRKKEILKYNGLHYW 437
            ::||:::...|...||:....:|..:.|..|:..|||:.|||:....:|.||.||::|.|.....
Worm   379 EIGELWIKGPQMMKGYWKKEQQTNELLDEHGFMRTGDIVYFDKNGETFICDRIKELIKVNAKQVA 443

  Fly   438 PTEIETVIAELSQVQDVCVVGIYDEREGDAAGALVVKSKGATI-SAKEIVEHVAKRLPATQKQLR 501
            |.|:|:||.|...|.||||.|:.|...|:...|.||..:|..: ::|.|::|:.::| |..|.::
Worm   444 PAELESVILEHDDVADVCVFGVDDASSGERPVACVVSKRGRDMETSKAIMKHINQKL-ARYKHIK 507

  Fly   502 AGVQFTDKLPANVNGKTMRKTARDVFV 528
            . ::|..::.....||.:|:..:..|:
Worm   508 E-IEFVSEIMRTGTGKLLRRAMKKAFL 533

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8834	NP_610779.1	CaiC	20..529	CDD:223395	134/547 (24%)
CG8834	NP_610779.1	AFD_class_I	46..519	CDD:302604	125/511 (24%)
acs-7	NP_495979.1	CaiC	12..540	CDD:223395	133/545 (24%)
acs-7	NP_495979.1	Firefly_Luc_like	35..524	CDD:213279	125/511 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24096
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010