| Sequence 1: | NP_001017915.1 | Gene: | INPP5D / 3635 | HGNCID: | 6079 | Length: | 1189 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001036740.2 | Gene: | sp3 / 42545 | FlyBaseID: | FBgn0038890 | Length: | 1142 | Species: | Drosophila melanogaster |
| Alignment Length: | 237 | Identity: | 54/237 - (22%) |
|---|---|---|---|
| Similarity: | 92/237 - (38%) | Gaps: | 71/237 - (29%) |
- Green bases have known domain annotations that are detailed below.
|
Human 146 SNENPRATETSRPSLSETLFQRLQSMDTSGLPEEHL-------KAIQDYLSTQLAQDSEFV--KT 201
Human 202 G-SSSLPHLKKLT--TLLCKELY------GEVIRTLPSLESLQRLFDQQLS-PGLRPRPQVPGEA 256
Human 257 NPINMVSKLSQLTSLLSSIEDKVKALLHEGPESPHRPSLIPPVTFEVKAESLGI---PQKMQLKV 318
Human 319 DVESGKLIIKKSKDGSEDKFYSHKKILQLIKSQKFLNKLVIL 360 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| INPP5D | NP_001017915.1 | SH2_SHIP | 1..102 | CDD:198206 | |
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 103..132 | ||||
| SH3-binding 1 | 124..129 | ||||
| INPP5c_SHIP1-INPP5D | 404..710 | CDD:197334 | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 870..906 | ||||
| PHA03307 | 899..>1127 | CDD:223039 | |||
| NPXY motif 1 | 912..915 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 922..1189 | ||||
| SH3-binding 2 | 969..974 | ||||
| Interaction with DAB2. /evidence=ECO:0000250 | 1016..1030 | ||||
| NPXY motif 2 | 1019..1022 | ||||
| SH3-binding 3 | 1040..1051 | ||||
| sp3 | NP_001036740.2 | COG5329 | <197..586 | CDD:227637 | |
| hSac2 | 663..768 | CDD:463592 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||