DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33012 and TRE2

DIOPT Version :9

Sequence 1:	NP_788335.2	Gene:	CG33012 / 36342	FlyBaseID:	FBgn0053012	Length:	912	Species:	Drosophila melanogaster
Sequence 2:	NP_014899.1	Gene:	TRE2 / 854430	SGDID:	S000005782	Length:	809	Species:	Saccharomyces cerevisiae

Alignment Length:	166	Identity:	30/166 - (18%)
Similarity:	60/166 - (36%)	Gaps:	27/166 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   157 MEVDVQRSSGSFLHWQMINMYQGIQNVVVKLSSKSSNSTSYLLVNSHYDSKPSSVGTGDAELMVV 221
            ::||:|.:         :.....|.|:|.|:..:..:..:.::..|.   ...:.||........
Yeast   409 IDVDLQTN---------VREKHFIPNIVGKIEGREQSDKAIIIAASR---NSINFGTTYPNFGTA 461

  Fly   222 TMLETLRLMATSEETF----LHPIVFLFNGAEEQPFHGSHSFISNHRWSANCK--ALVNLDSAGA 280
            .:|..::|....:..|    |..|.|:..|..|..:.||...:.........:  :|:::...|.
Yeast   462 ALLSIVQLFQEVKYKFGWKPLRNIYFISFGGTEFNYAGSSELVEQRLTPLKDEIYSLIDISQLGI 526

  Fly   281 GGREILFQGG--------PNHPWLMKQYKKSAKHPF 308
            ...| .::.|        ..||.|.|.:.::|...|
Yeast   527 PFAE-KYENGKTRGELSIETHPLLKKFFNRNAHGNF 561

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33012	NP_788335.2	M28_Fxna_like	103..410	CDD:193497	30/166 (18%)
TRE2	NP_014899.1	PA	249..392	CDD:238300
		M28_PMSA_TfR_like	417..643	CDD:349871	27/149 (18%)
		TFR_dimer	668..799	CDD:398094
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2234
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900