Protein Alignment CG33012 and PFF1

DIOPT Version :10

• Sequence 1: NP_788335.2
• Gene: CG33012 / 36342
• FlyBaseID: FBgn0053012
• Length: 912
• Species: Drosophila melanogaster
• Sequence 2: NP_009630.3
• Gene: PFF1 / 852366
• SGDID: S000000278
• Length: 976
• Species: Saccharomyces cerevisiae
• Alignment Length: 765
• Identity: 153/765 - (20%)
• Similarity: 268/765 - (35%)
• Gaps: 244/765 - (31%)

  Fly   143 ISKVRDEMRNDLYDMEVDVQRSSGSFLHWQMINMYQGIQNVVVKLSSKSSNSTSYLLVNSHYDSK 207
            :|..::..|:.|:..:.....||    .:..:..::. .|::|||..|:..... ||:::|:||.
Yeast   102 VSDDKESERSILFQQQDPFNESS----RFSRVTYFES-SNILVKLEGKNPEEEG-LLLSAHFDSV 160

  Fly   208 PSSVGTGDAELMVVTMLETLRLMATSEETFLHPIVFLFNGAEEQPFHGSHSFISNHRWSANCKAL 272
            |:..|..|..:.||::|..|:........  ..::|.||..||....|:.::. :|.||...|.:
Yeast   161 PTGYGATDDGMGVVSLLANLKYHIKHRPN--RTLIFNFNNNEEFGLLGASTYF-DHSWSNLTKYV 222

  Fly   273 VNLDSAGAGGREILFQGGPNHPWLMKQYKKSAK-HPFATTMAEEIFQADLIPSDTDFRIFRDFGP 336
            :||:..||||:.:||:.....  ..:.|::|.| :||..::.::.|.:..:.|:||::|:.:.|
Yeast   223 INLEGTGAGGKAVLFRTSDTS--TARIYQQSVKENPFGNSIYQQGFYSRYVRSETDYKIYEENG- 284

  Fly   337 VPGLDMAGCYNGFVYHTKFDRYKVISRGALQNTGDNVLSLVRSISNAEEMYDTEAHSEGHSVFFD 401
            :.|.|:|......:|||..|..:..|:.:|.:.....|.|  |...|....||.  .:..:.:||
Yeast   285 MRGWDVAFYKPRNLYHTIKDSIQYTSKASLWHMLHTSLQL--SAYVASNSLDTA--DQTPACYFD 345

  Fly   402 YLGLFFVYYTESTGTALNISFSLGAILVICLSLWRMAKVTDRRLGTYARAFGMQFLLAILGFLLA 466
            ::||.|...:..|                 |..|...                 |||  :..::|
Yeast   346 FIGLKFFVISAKT-----------------LFYWNCI-----------------FLL--VSPVVA 374

  Fly   467 LGFPLLMSVFYDAGDRTMTYFSNSWLVIGLFICPSIIGLVLPATLYLSLRPSEKIPHT------- 524
            :|..|:      :.|| ||:.|.|||....|......|:::.......:..|..:..:
Yeast   375 IGLYLI------SRDR-MTWKSYSWLSWTRFPLSLAAGIIVQKLFSNDIIRSNPLTFSRNYFWPI 432

  Fly   525 --YHLQIVGHAY-----------CVFMAVLCILLTVVGIRTAYLFM----------------MCV 560
              :..|::..:|           |..|..|.|:...:.:.|..||.                :.:
Yeast   433 SAFFTQVIFTSYVLINCSNFFFPCADMKSLSIIELFIILWTILLFTSKLLYSSDYRYTGLYPLSI 497

  Fly   561 FFYLG---------ALIINLATR------------------------------------------ 574
            ||.|.         ||.:.:.||
Yeast   498 FFLLSTIAAILRLLALALGMRTRKRLGRECRDHHSNYSSHSQIDMERDGQENLEQPQDQLTSSQD 562

  Fly   575 --------------------------------LHD------KG---------------------Y 580
                                            .||      ||                     |
Yeast   563 DQASIQDDNVSTTSAGPSHNVDEDHGMDSSSQQHDERVPLLKGSNSMEEGLSTRENSLKLEYTDY 627

  Fly   581 LWALVLCVCQILPYLYFTYLFHALLVI--TIPMTSRKGMDANPDLLISLECALGSILAMVFLAPL 643
            .|.:...:  |:|...| .||:::.||  .:..|.::|..|..|:|     ..|.:.:::...|:
Yeast   628 AWIIQFLL--IVPIPSF-ILFNSVDVIMDALNHTVQEGSKATFDVL-----RFGMVGSILIALPI 684

  Fly   644 LNLFRRPKAMIGGLTLVMFIFCMISVSDVGFPYRPTTNVMRLHFLEVHRKFYEFDGSISLED--- 705
            |..|.:...:...||.::|   :||.|.. ....|.||...|.        ..|..:|.|..
Yeast   685 LPFFYKVNYITISLTALLF---LISASKT-LLVHPFTNSNPLK--------VRFSQNIDLSQGNA 737

  Fly   706 SGYYFDLQDRRFENPLLD----------KINLTGITRVDDYCKTEMYCGL 745
            :..:...::..|..|:|.          .||.|.:|...:.|   ||.|:
Yeast   738 ASVHVLGREGNFLKPMLQDLPSIKYSSTHINCTSVTNGMELC---MYDGM 784

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33012	NP_788335.2	M28_Fxna_like	103..410	CDD:349872	71/267 (27%)
PFF1	NP_009630.3	M28_Fxna_like	50..354	CDD:349872	71/267 (27%)
		DUF2189	366..>443	CDD:470522	18/85 (21%)