DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG33012 and AT1G67420

DIOPT Version :9

Sequence 1:	NP_788335.2	Gene:	CG33012 / 36342	FlyBaseID:	FBgn0053012	Length:	912	Species:	Drosophila melanogaster
Sequence 2:	NP_001321979.1	Gene:	AT1G67420 / 843062	AraportID:	AT1G67420	Length:	943	Species:	Arabidopsis thaliana

Alignment Length:	950	Identity:	226/950 - (23%)
Similarity:	396/950 - (41%)	Gaps:	208/950 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 NVTLIELKQKSRFSK-QLEWYYSPAYLLFW-------------------VGLFFAVCYPL----- 86
            |...::::..|.||| .:..:.|.:.:.||                   ..|..|:.|.:
plant    24 NNRCLQVRDLSDFSKAPIRRFESISVMPFWKMSARDVTGFKFLFSLVFIYALMSAIVYSVLHMKF 88

  Fly    87 FNHLPTGVKIEEEANLPGTFVAQRAESILIRLDLM--------GPKIAGDYV-TEVEMVEFLLGE 142
            .:.||....:|..:.      |:..|.|.:..:.:        |.|.|..|: :::|||:
plant    89 ISPLPANAPLERFSE------ARAVEHIRVLAEEIDGRQEGRPGLKEAATYIKSQLEMVK----- 142

  Fly   143 ISKVRDEMRNDLYDMEVDVQRSSGS----FLHWQMINMYQGIQNVVVKLSSKSSNST-SYLLVNS 202
             .:....:|.::.:.:||     ||    ||...:...|:...|:::::||.:|..| :.:|:|:
plant   143 -ERAGPNLRVEVEETQVD-----GSFSMMFLGHSISLGYRNHTNILMRISSMNSLDTDASVLMNA 201

  Fly   203 HYDSKPSSVGTGDAELMVVTMLETLRLMATSEETFLHPIVFLFNGAEEQPFHGSHSFISNHRWSA 267
            ||||..:|.|.||....|.::||..||:..|......|::||||||||....|||.|::.|:...
plant   202 HYDSPVNSPGAGDCGSCVASLLELARLVVDSGWVPPQPVIFLFNGAEELFMLGSHGFMTKHKLKD 266

  Fly   268 NCKALVNLDSAGAGGREILFQGGPNHPWLMKQYKKSAKHPFATTMAEEIFQADLIPSDTDFRIF- 331
            ...|.:|::::|.||.:::.|.||. .|....|.::|.:|.|.:.|:::|  .:||.|||:|:|
plant   267 TIGAFINVEASGTGGIDLVCQSGPG-SWPSYVYSQAAVYPMAQSSAQDVF--PVIPGDTDYRMFA 328

  Fly   332 RDFGPVPGLDMAGCYNGFVYHTKFDRYKVISRGALQNTGDNVLSLVRSISNAEEM--------YD 388
            .|:..:||||:.....|:.|||.||....|..|::|..|:|::|::::.:::..:        .|
plant   329 EDYADIPGLDIIFLLGGYYYHTTFDTVDRIVPGSMQARGENLISVLKAFASSSRLKVASERKTLD 393

  Fly   389 TEAHSE--GHSVFFDYLGLFFVYYTESTGTALNISFSLGAILVICLS--LWRMAKVTDRRLGTYA 449
            .:|:|:  ..:||||||..|.|:|.......|:   ::.|.|.:|:.  |:.|...|...| ::.
plant   394 VDANSDMVERAVFFDYLTWFMVFYPRRVAFVLH---NIPAALFLCVPFFLYMMDPRTHPLL-SFF 454

  Fly   450 RAFGMQFLLAILGFLLALGFPLLMSVFYDAGDRTMTYFSNSWLVIGLFICPSIIGLVLPATLYLS 514
            .||....:....|.||.:..|:|.:|........|::|::|:|...:||..|..||::|..:
plant   455 WAFFKGVMHHFAGILLGVIVPVLFAVIRLFFAYPMSWFAHSYLAFLMFIPCSFFGLLIPRAI--- 516

  Fly   515 LRPSEKIPHTYHLQIVGHAYCV---------------FMAVLCILLTVVGIRTAYL-FMMCVFFY 563
               |:::.   |.|.|.....:               |.|.........|:...:: |::.:...
plant   517 ---SDRVS---HFQGVSSKKIMKVEPSDEARFWGAFGFYAFATSAYFFAGLNGGFMTFVISISML 575

  Fly   564 LGALIINLATRLHDKG-------YLWALVLCVCQILPYLYFTYLFHALLVITIPMTSRKGMDANP 621
            ||.:...|:.:.:...       |:.|||.|:      ||..|....|.::.|..|...|....|
plant   576 LGWIAFYLSVKSYGYNSIKSPMFYVIALVPCL------LYSLYFGGILTLLLIEKTGMMGAIPPP 634

  Fly   622 DLLISLECALGSILAMV---FLAPLLNLFRRPKAMIGGLT-LVMFIFCMISVSDVGFPY---RPT 679
            ......:.|:.:::.:|   .|.|::.:..|..|....|. |:.|...|::||...|||   .|.
plant   635 YGFYLADVAVAAVIGIVTGLCLGPIIPICDRWLAKSSILKFLLHFTVVMLAVSSQFFPYSKDAPK 699

  Fly   680 TNVMRLHFLEVHRKFYEFDGSISLEDSGYYFDLQDRRFENPLLDKINLTGITRVDDYCKTEMYCG 744
            ..|::..|:..       .|:   |.:|..:||       .::|..::..|.:.......|::.|
plant   700 RVVLQHTFIST-------GGN---EITGSSYDL-------AVIDSNSMEFIFKHAPEVAKELHVG 747

  Fly   745 LPCFNHRWCSAVNDARWLPRDEPVDLPGT-------------------PILQ-------FLNKT- 782
             |.|:.....|.....|:.. .|:....|                   |:||       |.|.|
plant   748 -PSFSLGNAEASPQEAWMAL-FPISCVLTTNGRFPAKANNILERYSQFPLLQAHKPQTTFENGTR 810

  Fly   783 ---------VLGTE------------SAPRALYYFVVS----SGPPRMSFFVQPRDGVRMLSWSF 822
                     ::|..            |..|:|....|:    :||              :..|||
plant   811 RVHLELSLGLVGLHKELLLVLLVINYSICRSLEEIWVTVLNITGP--------------LSGWSF 861

  Fly   823 LKGMLDNPSVYK--PPYHIFFGYGSDDSPVEFYFEMTKDD 860
            ..|....|.:..  ||.:|....|:.|....|:.|.:.::
plant   862 ADGKPPAPELPPGGPPSYILRLSGNSDEKWNFWLEASSEE 901

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33012	NP_788335.2	M28_Fxna_like	103..410	CDD:193497	103/331 (31%)
AT1G67420	NP_001321979.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2234
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H121891
Inparanoid	1	1.050	212	1.000	Inparanoid score	I1244
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D248924at2759
OrthoFinder	1	1.000	-	-		FOG0000591
OrthoInspector	1	1.000	-	-		otm3269
orthoMCL	1	0.900	-	-		OOG6_101747
Panther	1	1.100	-	-	O	PTHR12147
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X435
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.830