DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33012 and naalad2

DIOPT Version :9

Sequence 1:	NP_788335.2	Gene:	CG33012 / 36342	FlyBaseID:	FBgn0053012	Length:	912	Species:	Drosophila melanogaster
Sequence 2:	NP_956571.1	Gene:	naalad2 / 393247	ZFINID:	ZDB-GENE-040426-1025	Length:	745	Species:	Danio rerio

Alignment Length:	298	Identity:	47/298 - (15%)
Similarity:	101/298 - (33%)	Gaps:	88/298 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 SEHSDTSYTENKKNTVQLVTDGIDPEEGCSNVTLIELKQKSRFSKQLEWYYSPAYLLFWVGLFFA 81
            |.|...::.|..|..:..:..|.|.|.....:.:...:.:...:::.|.|.|
Zfish   483 SWHKRDNWPEKDKPWISKLGSGSDFEAYFIRLGITSGRARYTKNRKTERYSS------------- 534

  Fly    82 VCYPLFNHL------------PTGVKIEEEANLPGTFVAQRAESILIRLDLMGPKIAGDYVTEVE 134
              ||:::.:            |...::|..|.:.|..:...|:|.::.||.:      :|.|.:.
Zfish   535 --YPVYHSVYETYEIVERFYDPRFRRLEAVARVRGGLIFSLADSAVLPLDCV------EYATSLS 591

  Fly   135 MVEFLLGEISKVRDEMRNDLYDMEVDVQRSSGSFLHWQMINMYQGIQNVVVKLSSKSSNSTSYLL 199
            .....:.:::|...|                             .:|..||...|..|.:.::.:
Zfish   592 TYANSIHQLAKKHPE-----------------------------AMQQYVVSFDSLFSAAENFTV 627

  Fly   200 VNSHYDSKPSSVGTGDAELMVVTMLETLRLMATSEETFLHPIVFLFNGAEEQPFH-------GSH 257
            ....:..:...:.:.:|  :.|.|:.. :||.. |..|:.|:     |...:||:       .||
Zfish   628 AARDFHQRLDQLDSSNA--LAVRMVND-QLMYL-ERAFIDPL-----GLPGRPFYRHIIFAPSSH 683

  Fly   258 SFISNHRWSANCKALVNLDSAGAGGREILFQGGPNHPW 295
            :..:...:.....||.::::|..          |.:.|
Zfish   684 NKYAGESFPGIYDALFDIENAAE----------PENAW 711

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33012	NP_788335.2	M28_Fxna_like	103..410	CDD:193497	32/200 (16%)
naalad2	NP_956571.1	Zinc_peptidase_like	47..>102	CDD:301362
		PA_GCPII_like	108..333	CDD:239036
		M28_PSMA_like	341..581	CDD:193568	18/112 (16%)
		TFR_dimer	618..733	CDD:282153	19/113 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2234
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900