DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33012 and Naalad2

DIOPT Version :9

Sequence 1:	NP_788335.2	Gene:	CG33012 / 36342	FlyBaseID:	FBgn0053012	Length:	912	Species:	Drosophila melanogaster
Sequence 2:	NP_001100272.1	Gene:	Naalad2 / 300384	RGDID:	1305872	Length:	778	Species:	Rattus norvegicus

Alignment Length:	375	Identity:	76/375 - (20%)
Similarity:	116/375 - (30%)	Gaps:	109/375 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   169 LHWQMINMYQGIQNVVVKLSSKSSNSTSYLLVNSHYDS------KPSSVGTGDAELMVVTMLETL 227
            :|...||....|.||:..:.. |:....|:::..|.||      .|:   ||.|.|.     |..
  Rat   372 MHVHNINKITRIYNVIGTIRG-STEPDRYVILGGHRDSWVFGGIDPT---TGTAVLQ-----EIA 427

  Fly   228 RLMATSEETFLHP---IVFLFNGAEEQPFHGSHSFISNHRWS-ANCK-------ALVNLDSAGAG 281
            |...........|   |:|....|||      ...:.:..|: .|.|       |.:|.|||..|
  Rat   428 RSFGKLVNGGWKPRRTIIFASWDAEE------FGLLGSTEWAEENAKILQERSIAYINSDSAIEG 486

  Fly   282 GREILFQGGPNHPWLMKQYKKSAKHP----FATTMAEEIFQADLIP------------SDTDFR- 329
            ...:.....|....|:.:..:....|    .:.::.|...:.|..|            |.:||.
  Rat   487 NYTLRVDCTPLLHQLVYKVAREISSPDDGFESKSLYESWLEKDPSPENKERPRINKLGSGSDFEA 551

  Fly   330 IFRDFGPVPG---------LDMAGCYNGFVYHTKFDRYKVIS----------------RGAL--- 366
            .|:..|...|         .|....|.  ||||.::.::::.                ||||
  Rat   552 YFQRLGIASGRARYTKNKKTDKYSSYP--VYHTIYETFELVQNFYDPTFKKQLSVAQLRGALVYE 614

  Fly   367 -----------QNTGDNVLSLVRSISNAEEMYDTEAHSEGHSVFFDYLGLFFVYYTESTGTALNI 420
                       |:....:.:...||.|..:.:|.:...  |.|.||.|......::|:..
  Rat   615 LADCVVIPFNIQDYAKALKNYAASIFNLSKKHDQQLRD--HGVSFDPLFSAVKNFSEAAS----- 672

  Fly   421 SFSLGAILVICLSLWRMAKVTDRRLGTYARAFGMQFLLAILGFLLALGFP 470
                        ...|.....|....|..|....|.:|....|:..||.|
  Rat   673 ------------DFHRRLTQVDLNNPTAVRIMNDQQMLLERAFIDPLGLP 710

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33012	NP_788335.2	M28_Fxna_like	103..410	CDD:193497	65/313 (21%)
Naalad2	NP_001100272.1	Zinc_peptidase_like	86..>143	CDD:417508
		PA_GCPII_like	148..374	CDD:239036	0/1 (0%)
		M28_PSMA_like	<382..623	CDD:349942	52/257 (20%)
		TFR_dimer	655..774	CDD:398094	15/73 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2234
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900