Protein Alignment CG33012 and NAALADL2

DIOPT Version :9

• Sequence 1: NP_788335.2
• Gene: CG33012 / 36342
• FlyBaseID: FBgn0053012
• Length: 912
• Species: Drosophila melanogaster
• Sequence 2: XP_011510914.1
• Gene: NAALADL2 / 254827
• HGNCID: 23219
• Length: 805
• Species: Homo sapiens
• Alignment Length: 393
• Identity: 72/393 - (18%)
• Similarity: 137/393 - (34%)
• Gaps: 129/393 - (32%)

  Fly     3 NMEK--HNGGFEEDKL--SEHSDTSYTENKKNTVQLVTDGIDPEEGCSNVTLIELKQKSRFSKQL 63
            :|||  ...||::.:|  :|:.:..::|    |:.|..|.|.|          ....|.||.:..
Human    61 DMEKELEESGFDQFQLDGAENQNLGHSE----TIDLNLDSIQP----------ATSPKGRFQRLQ 111

  Fly    64 E-----WYYS-------------------PAYLLFWVGLFFAVCYPLFNHLPTGVKIEEEANLPG 104
            |     .:|:                   .|.:||..|:.  :.|.:..:.|:      :|...|
Human   112 EESDYITHYTRSAPKSNRCNFCHVLKILCTATILFIFGIL--IGYYVHTNCPS------DAPSSG 168

  Fly   105 TFVAQRAESILIRLDLMGPKIAGDYVTEVEMVEFLLGEISKVRDEMRN--DLYDMEVDVQRSSGS 167
            |...|..:.||..:                       :...::...||  .||..|.|::.|...
Human   169 TVDPQLYQEILKTI-----------------------QAEDIKKSFRNLVQLYKNEDDMEISKKI 210

  Fly   168 FLHWQMINMYQGIQ--NVVVKLSSKSSNSTSYLLVNS----HYDSKP------------------ 208
            ...|..:.: :.:|  |..|.|.....:.::..|.:|    |.:.:|
Human   211 KTQWTSLGL-EDVQFVNYSVLLDLPGPSPSTVTLSSSGQCFHPNGQPCSEEARKDSSQDLLYSYA 274

  Fly   209 --SSVGTGDAELMVVT--MLETLRLM-----ATSEETFLH----PIVFLFNGAEEQPFHGSHSFI 260
              |:.||..||::.|:  |.:.|:.:     .|::...|.    |:::..:..|:..|.|...:|
Human   275 AYSAKGTLKAEVIDVSYGMADDLKRIRKIKNVTNQIALLKLGKLPLLYKLSSLEKAGFGGVLLYI 339

  Fly   261 SNHRWSANCKALVN------LDSAGAGGREILFQGGPNHPWLMKQYKKSAKHPFATTMAEEIFQA 319
            .    ..:....||      :.|...||.    ...|.:|.:.:.:::|..:  .|::..:...|
Human   340 D----PCDLPKTVNPSHDTFMVSLNPGGD----PSTPGYPSVDESFRQSRSN--LTSLLVQPISA 394

  Fly   320 DLI 322
            .|:
Human   395 PLV 397

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33012	NP_788335.2	M28_Fxna_like	103..410	CDD:193497	47/265 (18%)
NAALADL2	XP_011510914.1	Peptidases_S8_S53	268..420	CDD:299169	26/140 (19%)
		Zinc_peptidase_like	437..659	CDD:301362
		TFR_dimer	686..>744	CDD:282153

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2234
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900