Protein Alignment CG33012 and B0495.7

DIOPT Version :9

• Sequence 1: NP_788335.2
• Gene: CG33012 / 36342
• FlyBaseID: FBgn0053012
• Length: 912
• Species: Drosophila melanogaster
• Sequence 2: NP_495618.1
• Gene: B0495.7 / 174245
• WormBaseID: WBGene00015206
• Length: 895
• Species: Caenorhabditis elegans
• Alignment Length: 951
• Identity: 272/951 - (28%)
• Similarity: 444/951 - (46%)
• Gaps: 163/951 - (17%)

  Fly     4 MEKHNGGFEE--DKLSEHSDTSYTENKKNTVQLVTDGIDPEEGCSNVTLIELKQKSRFSKQLEWY 66
            |.:..||..|  |:|:         |.||         .||:          .|:::..::...:
 Worm     1 MLRRRGGPNELRDELN---------NSKN---------QPED----------DQRTKRGRESIGF 37

  Fly    67 YSPAYLLFWVGLFFAVCYPLFNHLPT---GVKIEEEANLPGTFVAQRAESILIRLDLMGPKIAGD 128
            ....|.:..|.:.:|....|...:|.   |...|:       |..|||..:|.:|..:|.:.:|.
 Worm    38 RHWIYFVLTVAIVYAGVVALHRKMPAVRDGTSFED-------FSEQRARVLLKQLTALGSRPSGS 95

  Fly   129 YVTEVE---MVEFLLGEISKVRDEMRNDLYDMEVDVQRSSGSF-LHW--QMINMYQGIQNVVVKL 187
            ...||:   |::..:|:|..|.||:  .:..:|.||||.||.| |.:  .....|..|.||||::
 Worm    96 DNLEVKAFGMIQDRIGKIHSVVDEV--GVNRLESDVQRPSGCFDLKFLSSFTLCYHKITNVVVRI 158

  Fly   188 SSKSSNSTSYLLVNSHYDSKPSSVGTGDAELMVVTMLETLRLMATSEETFLHPIVFLFNGAEEQP 252
            ..|...|.:.||:|.|:|:.|.:.|..|..:....|::.|.::|.|:....:.:|||||||||..
 Worm   159 GPKKGPSGNSLLLNCHFDTMPDTPGATDDAVACTIMMDVLEVLAHSKTELENDVVFLFNGAEENF 223

  Fly   253 FHGSHSFISNHRWSANCKALVNLDSAGAGGREILFQGGPNHPWLMKQYKKSAKHPFATTMAEEIF 317
            ...:|.||:.|.|..:.:|.:||:..|:||||||||.||.:.||::.|.::|.|||.:.:|:|||
 Worm   224 LQAAHGFINQHPWRHDIRAFINLEGTGSGGREILFQAGPGNSWLLQTYLENAPHPFCSVLAQEIF 288

  Fly   318 QADLIPSDTDFRIFRDFGPVPGLDMAGCYNGFVYHTKFDRYKVISRGALQNTGDNVLSLVRSISN 382
            |:.:||||||||||||:|.:.|||:|...||:.|||:||....|..||:|..|:|||::||:|..
 Worm   289 QSGIIPSDTDFRIFRDYGRISGLDIAYTKNGWFYHTEFDEEWRIEPGAIQRAGENVLAVVRAILK 353

  Fly   383 AEEM-----YDTEAHSEGHSVFFDYLGLFFVYYTESTGTALNISFSLGAILVICLSLWRMAKVTD 442
            :..:     :|    .|...||:|.:|||.|||:.:.|..||.........::.|      ::.:
 Worm   354 SPYLEKPATFD----EENRWVFYDVVGLFTVYYSVNVGKLLNYIACFATYFLVVL------RIRN 408

  Fly   443 R--RLGTYARAFG---MQFLLAILGFLLALGFPLLMSVFYDAGDRTMTYFSNSWLVIGLFICPSI 502
            |  .:|..|.||.   :.||..::..||.:.|.:.|       |..|.::....:|..|::.|.:
 Worm   409 RLYSVGDLAIAFKHHVVAFLAMVITMLLIIAFVVQM-------DLVMCWYKMPEIVGALYVLPML 466

  Fly   503 IGLVLPATLYLS---LRPSEKIPHTYHLQIVGHAYCVFMAVLCILLTVVGIRTAYLFMMCVFFYL 564
            |...:..:.|..   :|..|.:  .|...::..|..:|      |:|...:.:|       |:.|
 Worm   467 IAGAIVHSHYADNNRIRNVEMV--QYDTILLSFASILF------LMTFYNLSSA-------FYVL 516

  Fly   565 GALIINLATRLHDKGYLWALVL--CVCQILP-YLYFTYLF-------HALLVIT------IPMTS 613
            ..||:.:...:    .:|||.|  .:.::.| .|:||.||       .|...|:      :|:..
 Worm   517 NNLILPVFKDI----IIWALGLFGVIRRVTPRVLFFTQLFCFLPTFVFAAYAISQCVDFFVPVMG 577

  Fly   614 RKGMDANPDLLISLECALGSILAMVFLAPLLNLF---RRPKAMIGGLTLVMFIFCMISV-SDVGF 674
            |.|...||:.::.   .||.::|..|:..:.|||   ||...:|..|..:..:|.::.: :.||.
 Worm   578 RLGNAINPEFIMG---PLGLVIASGFILFVNNLFYISRRMNYIIRLLFAIFALFILVLITTKVGN 639

  Fly   675 PY---RPTTNVMRLHFLEVHRKFYEFDGSISLEDSGYYFDLQDRRFENPLLDKI--------NLT 728
            ||   .....:.|:..|..:|..|:|:|.::.:|:..:....|.|..:.|.|..        |.|
 Worm   640 PYEYSHENPRLRRIIALHANRTIYDFEGHLTQKDNALFVHSLDYRGASDLPDHSFLQGSSAPNCT 704

  Fly   729 GITRVDDYCKTEMYCGLPCFNHRWCSAVND------ARWLPRDEPVDLPGTPILQFLNKTVLGTE 787
            |:  ||:||:...|           :|:::      :.|:|...||.||....|:.:::..:|
 Worm   705 GV--VDEYCRMPYY-----------TAIHELFPPEQSLWVPVPSPVVLPYPIDLKLVSRHAMG-- 754

  Fly   788 SAPRALYYFVVSSGPPRMSFFVQPRDGVRMLSWSFLKGMLDNPSV-YKPPYHIFFGYGSDDSPV- 850
              ......|.:..|..:||..|.|.:...:|||||..  :|.... .:..|.:|..||.:...|
 Worm   755 --ENLNLTFEIRGGYDKMSLHVTPLNDYDLLSWSFTD--IDIKEFGRRQTYFVFMTYGHEAPEVR 815

  Fly   851 EFYFEMTKDDGNFDGPV----VELGISGHYMSHLSKRDATT 887
            .|:..:...:|....|.    :||.::.|| :|...:|..|
 Worm   816 RFWILLKNKNGVAPDPEKHENIELSVATHY-AHGIYQDTET 855

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33012	NP_788335.2	M28_Fxna_like	103..410	CDD:193497	129/317 (41%)
B0495.7	NP_495618.1	M28_Fxna_like	70..382	CDD:193497	130/324 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160158696
Domainoid	1	1.000	230	1.000	Domainoid score	I1390
eggNOG	1	0.900	-	-		E1_COG2234
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H121891
Inparanoid	1	1.050	359	1.000	Inparanoid score	I1290
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG59376
OrthoDB	1	1.010	-	-		D152011at33208
OrthoFinder	1	1.000	-	-		FOG0000591
OrthoInspector	1	1.000	-	-		mtm4849
orthoMCL	1	0.900	-	-		OOG6_101747
Panther	1	1.100	-	-	O	PTHR12147
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X435
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.810