Protein Alignment CG8839 and FAAH2

DIOPT Version :10

• Sequence 1: NP_610764.1
• Gene: CG8839 / 36340
• FlyBaseID: FBgn0033717
• Length: 529
• Species: Drosophila melanogaster
• Sequence 2: NP_777572.2
• Gene: FAAH2 / 158584
• HGNCID: 26440
• Length: 532
• Species: Homo sapiens
• Alignment Length: 522
• Identity: 235/522 - (45%)
• Similarity: 328/522 - (62%)
• Gaps: 19/522 - (3%)

  Fly    13 GYIFGIL-QACIRFVFRLIYGQK--GESVPPITDAILLESATSLARKIRKQELSSVQVLESFIRR 74
            |::.|:: :|.:     ::.|.|  .::..|:|:.:||.|...||:.||::::..:.|::::|.|
Human    18 GFLIGLVGRAAL-----VLGGPKFASKTPRPVTEPLLLLSGMQLAKLIRQRKVKCIDVVQAYINR 77

  Fly    75 IKEVNPILNCVVDERYDQALKEAAEADALIKSGQYSTEELEKEKPFLGVPITTKDCISVKGMLHT 139
            ||:|||::|.:|..|:::|:|||...|..:...|.....||.:.||||||:|.|:...::||.::
Human    78 IKDVNPMINGIVKYRFEEAMKEAHAVDQKLAEKQEDEATLENKWPFLGVPLTVKEAFQLQGMPNS 142

  Fly   140 AGLFERRDVRAARDADAMALMRKAGAIPIALTNVSEVCMWWESNNTVHGRTRNAYDTNRIVGGSS 204
            :||..|||..|..||..:||::.|||||:.:||.||:|||:||:|.::||:.|.||...||||||
Human   143 SGLMNRRDAIAKTDATVVALLKGAGAIPLGITNCSELCMWYESSNKIYGRSNNPYDLQHIVGGSS 207

  Fly   205 GGEGCIQSAAASAFGLGSDIGGSIRMPAFFNGIFGHKPSKLVVSNVGQFPAPFSAEQNSFLGLGP 269
            |||||..:||.|..|:|||||||||||||||||||||||..||.|.||||....| |..||..||
Human   208 GGEGCTLAAACSVIGVGSDIGGSIRMPAFFNGIFGHKPSPGVVPNKGQFPLAVGA-QELFLCTGP 271

  Fly   270 MSRFAEDLRPMLKIMAGEKAALLNLDEDVDLTKMKFFYQESDGGGRLVSAVDPDLREAMNRVAQH 334
            |.|:||||.||||:|||.....|.||..|.|..:||::.|.|||..|:|.||.||.....:|..|
Human   272 MCRYAEDLAPMLKVMAGPGIKRLKLDTKVHLKDLKFYWMEHDGGSFLMSKVDQDLIMTQKKVVVH 336

  Fly   335 LREKFGNQKVERIQLPHFRQSAAIWFANMRDDSGHG------FAYQLGNLNHDINTYLELFKWFF 393
            |....| ..|:.::|...:.|..:|.| |....||.      |...||:....::...||.||..
Human   337 LETILG-ASVQHVKLKKMKYSFQLWIA-MMSAKGHDGKEPVKFVDLLGDHGKHVSPLWELIKWCL 399

  Fly   394 GASKHTFIGLSTAIMDSAQCKHGSPKYDHLVRKRNELREELQSLLGDNGVLIYPTHPTVAPYHNE 458
            |.|.:|...:..|:::. :.::.:.||.........||:||..:|||:||.:||:||||||.|:.
Human   400 GLSVYTIPSIGLALLEE-KLRYSNEKYQKFKAVEESLRKELVDMLGDDGVFLYPSHPTVAPKHHV 463

  Fly   459 PITRPINFAYTGIVNVLGFPATAVPLGKLGSEGLPLGVQIIANFNQDRLCLAVAEELERAFGGWA 523
            |:|||.||||||:.:.||.|.|..||| |.::|||||:|::|....|.|.||||:.||:.||||.
Human   464 PLTRPFNFAYTGVFSALGLPVTQCPLG-LNAKGLPLGIQVVAGPFNDHLTLAVAQYLEKTFGGWV 527

  Fly   524 KP 525
            .|
Human   528 CP 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8839	NP_610764.1	GatA	49..525	CDD:439924	225/481 (47%)
FAAH2	NP_777572.2	GatA	45..524	CDD:439924	224/483 (46%)