DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG8839 and Faah

DIOPT Version :9

Sequence 1:NP_610764.1 Gene:CG8839 / 36340 FlyBaseID:FBgn0033717 Length:529 Species:Drosophila melanogaster
Sequence 2:NP_034303.3 Gene:Faah / 14073 MGIID:109609 Length:579 Species:Mus musculus


Alignment Length:556 Identity:150/556 - (26%)
Similarity:230/556 - (41%) Gaps:118/556 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly    42 TDAILLESATSLARKIRKQELSSVQVLESFIRRIKEVNPILNCVVDERYD--QALKEAAEADALI 104
            ::|:|......|.:|::..|||...||.:::.:..|||...|||.....|  ..|.:|.....| 
Mouse    71 SEALLALPLLQLVQKLQSGELSPEAVLFTYLGKAWEVNKGTNCVTSYLTDCETQLSQAPRQGLL- 134

  Fly   105 KSGQYSTEELEKEKPFLGVPITTKDCISVKGMLHTAGLFERRDVRAARDADAMALMRKAGAIPIA 169
                            .|||::.|:|.|.||...|.||.....|.:..|...:.:::..||:|..
Mouse   135 ----------------YGVPVSLKECFSYKGHASTLGLSLNEGVTSESDCVVVQVLKLQGAVPFV 183

  Fly   170 LTNVSEVCMWWESNNTVHGRTRNAYDTNRIVGGSSGGEGCIQSAAASAFGLGSDIGGSIRMPAFF 234
            .|||.:..:.::.:|.:.|:|.|.:..::..||||||||.:..:..|..|||:|||||||.|:.|
Mouse   184 HTNVPQSMLSYDCSNPLFGQTMNPWKPSKSPGGSSGGEGALIGSGGSPLGLGTDIGGSIRFPSAF 248

  Fly   235 NGIFGHKPSKLVVSNVGQFPAPF--SAEQNSFLGLGPMSRFAEDLRPMLKIMAGEKAALLNLDED 297
            .||.|.||:...:|..|.....:  :|.|   |.:|||:|..:.|...:|.:..|.  |..||..
Mouse   249 CGICGLKPTGNRLSKSGLKSCVYGQTAVQ---LSVGPMARDVDSLALCMKALLCED--LFRLDST 308

  Fly   298 V-----------DLTKMKFFYQESDGGGRLVSAVDPDLREAMNRVAQHLREKFGNQKVERI--QL 349
            :           ....::..|.|:|.    .:...|.:|.|:....|.| |..|:..|..:  .:
Mouse   309 IPPLPFREEIYRSSRPLRVGYYETDN----YTMPTPAMRRAVMETKQSL-EAAGHTLVPFLPNNI 368

  Fly   350 PHFRQ--SAAIWFANMRDDSGHGFAYQ---------LGNLNHDINTYLELFKWF-----FGASKH 398
            |:..:  ||...|:    |.|..|...         ||    |:...|:|.:||     | ..|.
Mouse   369 PYALEVLSAGGLFS----DGGCSFLQNFKGDFVDPCLG----DLVLVLKLPRWFKKLLSF-LLKP 424

  Fly   399 TFIGLSTAIMDSAQCKHGSPKYDHLVRKRNELREELQSLLGD------NGVLIYPTHPTVAPY-- 455
            .|..|:..:  ::.|...:.|   |...::|:....||::..      :.||.    |.:.|.  
Mouse   425 LFPRLAAFL--NSMCPRSAEK---LWELQHEIEMYRQSVIAQWKAMNLDVVLT----PMLGPALD 480

  Fly   456 HNEPITRPINFAYTGIVNVLGFPATAVPLGKLGSE----------------------------GL 492
            .|.|.......:||.:.|.|.|||..||:..:.:|                            ||
Mouse   481 LNTPGRATGAISYTVLYNCLDFPAGVVPVTTVTAEDDAQMEHYKGYFGDMWDNILKKGMKKGIGL 545

  Fly   493 PLGVQIIANFNQDRLCLAVAEELERAFGGWAKPEVR 528
            |:.||.:|...|:.|||....|:||..    .||.|
Mouse   546 PVAVQCVALPWQEELCLRFMREVERLM----TPEKR 577

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG8839NP_610764.1 GatA 42..525 CDD:223232 147/551 (27%)
PRK07488 49..520 CDD:236030 145/539 (27%)
FaahNP_034303.3 Amidase 95..562 CDD:279733 135/511 (26%)
Substrate binding. /evidence=ECO:0000250 238..241 2/2 (100%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 107 1.000 Domainoid score I6507
eggNOG 1 0.900 - - E1_COG0154
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 142 1.000 Inparanoid score I4451
Isobase 1 0.950 - 0.69812 Normalized mean entropy S4795
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 1 1.000 - - otm42825
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X256
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
87.810

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