DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Den1 and CG1503

DIOPT Version :9

Sequence 1:	NP_001163126.1	Gene:	Den1 / 36339	FlyBaseID:	FBgn0033716	Length:	249	Species:	Drosophila melanogaster
Sequence 2:	NP_001285511.1	Gene:	CG1503 / 33090	FlyBaseID:	FBgn0031157	Length:	307	Species:	Drosophila melanogaster

Alignment Length:	250	Identity:	84/250 - (33%)
Similarity:	131/250 - (52%)	Gaps:	20/250 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 QNQNTNRRRPRFTNNSFHTKMGSN------SKADPISLTFHDSCLRMSDVQLLHGPH-WLNDQIL 72
            :.:|.|:.|...|:.|...:.||.      ::...::|.|.|..||.||||||...: .:|::::
  Fly    53 KGKNKNKIRDSKTSTSLALERGSGDGPHQLAEVSLVALRFMDISLRHSDVQLLQSANEGVNERLV 117

  Fly    73 SFYYEYLAHMKYKTNADLHFIAPEITQCMKYMGDQELKQLLDQSNTTGKPFIFFALNDNETTDAG 137
            :|||.||.|.:|::..||||:.|.:...:::|..::|..::.......|.||...|:   |....
  Fly   118 AFYYAYLQHRRYRSELDLHFLNPGLAARLRHMNMRQLWAMVRDRRLNEKQFILVPLS---THPRP 179

  Fly   138 GSHWSLLVFSRPEKTFYHFDSYGNNNTGNSLELMNKIKDLLGVRMAKFRPMRCLQQ--------A 194
            ..||||||.|||:..|||:||..|.::..:..:...::..|..........|||||        .
  Fly   180 HGHWSLLVISRPDSKFYHYDSLDNCHSPLAASVSETLRAPLEAWKFALVTGRCLQQERQAAGKEG 244

  Fly   195 NGYD--CGIHVICMTDHIADYLNRYEVIDGLPSLHIDTVKAKRTELLKLILSLGG 247
            :|.|  .|||::|||||:|||:.|.........:.:|.:.|.||.|::||.||||
  Fly   245 SGRDPASGIHLMCMTDHVADYVARCGYATSSLLIAVDQIAAMRTHLVELIQSLGG 299

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Den1	NP_001163126.1	Peptidase_C48	66..204	CDD:304959	46/147 (31%)
CG1503	NP_001285511.1	Peptidase_C48	117..>205	CDD:304959	34/90 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469701
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2828
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	99	1.000	Inparanoid score	I2191
Isobase	1	0.950	-	0	Normalized mean entropy	S3849
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1313098at2759
OrthoFinder	1	1.000	-	-		FOG0004372
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.750