Protein Alignment garz and PSD2

DIOPT Version :9

• Sequence 1: NP_610761.2
• Gene: garz / 36337
• FlyBaseID: FBgn0264560
• Length: 1983
• Species: Drosophila melanogaster
• Sequence 2: XP_011535998.1
• Gene: PSD2 / 84249
• HGNCID: 19092
• Length: 791
• Species: Homo sapiens
• Alignment Length: 649
• Identity: 144/649 - (22%)
• Similarity: 221/649 - (34%)
• Gaps: 198/649 - (30%)

  Fly   556 RNCAASKNSSNNRESLPEAAPATGGSRHSRHNSGLEGIVIDSGNSVAAEEKVENIASFINASSHR 620
            |...:|..|.|....|...|...|     .|..|.:|   ..|:....||..:.:.:  :||...
Human   243 RRSISSSRSENVLSRLSLMAMPNG-----FHEDGPQG---PGGDEDDDEEDTDKLLN--SASDPS 297

  Fly   621 LRLQSGGEGVGITSEQLAKVKQKKRLLSQGTERFNQRP-EKGIQYLQE--HGILNA--ELDPMQ- 679
            |:     :|:..:..:|:.        |:|.|..:..| ..|.|.:.|  |.:...  .|:..|
Human   298 LK-----DGLSDSDSELSS--------SEGLEPGSADPLANGCQGVSEAAHRLARRLYHLEGFQR 349

  Fly   680 --VALFLRENPGLDKKMIGEYISKKKNVDSKILINFVDSFDFTGLRVDQALRLYLETFRLPGEAP 742
              ||..|.:|....:.:.|||:|               .|||:||.:|.|||.:|:.|.|.||..
Human   350 CDVARQLGKNNEFSRLVAGEYLS---------------FFDFSGLTLDGALRTFLKAFPLMGETQ 399

  Fly   743 LIFLVLEHFSDHWHKQNQDPFANVDAAFRLAYAIIMLNMDQHNSNAKRLNVPMTLEDFTKNLRGL 807
            ....||.|||..:.:.|.|...:.|....|..|:::||.|.|..|   :...|:.:.|..||..|
Human   400 ERERVLTHFSRRYCQCNPDDSTSEDGIHTLTCALMLLNTDLHGHN---IGKKMSCQQFIANLDQL 461

  Fly   808 NGGEDFDQEMLAQVFNAIKNEEIVMPAEQTGLVRENYQWKV---LLRRGDTHDGHFHYVHDASYD 869
            |.|:||.:::|..::|:||||::              :|.:   .||:
Human   462 NDGQDFAKDLLKTLYNSIKNEKL--------------EWAIDEDELRK----------------- 495

  Fly   870 VEIFNIVWGASLSALSFMFDKSTETGYQ---RTLAGFSK--------SAAISAHYNL----HSDF 919
                         :||.:.|....||.:   |.|.|.:.        ||....|..|    |:|.
Human   496 -------------SLSELVDDKFGTGTKKVTRILDGGNPFLDVPQALSATTYKHGVLTRKTHADM 547

  Fly   920 DA-----------LVLTLCKFTTLLSSVEQHEPAPANNETQQAVNFGLNGKAQAAMRTVFLLVHD 973
            |.           ....:.|.|.|....:::.|..|.:|          |..:.|:|....|...
Human   548 DGKRTPRGRRGWKKFYAVLKGTILYLQKDEYRPDKALSE----------GDLKNAIRVHHALATR 602

  Fly   974 YGDCLRES---------WKHIL----------------DLYLQLFRLKLLPKSLIEVEDFC---- 1009
            ..|..::|         |:..|                :|...:|.....|.::..::.||
Human   603 ASDYSKKSNVLKLKTADWRVFLFQAPSKEEMLSWILRINLVAAIFSAPAFPAAVSSMKKFCRPLL 667

  Fly  1010 ---------------EANGKAMLILE-------------KPREKQESGLFSSLYSFISSEGQREP 1046
                           ..|....|..|             |.:|.:|..|.....:|   |..|..
Human   668 PSCTTRLCQEEQLRSHENKLRQLTAELAEHRCHPVERGIKSKEAEEYRLKEHYLTF---EKSRYE 729

  Fly  1047 TYEEQDFIKLGRKCIKECQLDQMLQESKFVQLESLQELLKCVLALLKAPQGHKSIGLPYAEDQT 1110
            ||     |.|....||....|....|::...||.....|:...:.....|||.: |....:|.|
Human   730 TY-----IHLLAMKIKVGSDDLERIEARLATLEGDDPSLRKTHSSPALSQGHVT-GSKTTKDAT 787

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
garz	NP_610761.2	COG5307	346..>1062	CDD:227623	131/599 (22%)
		Sec7_N	370..512	CDD:289549
		Sec7	643..830	CDD:279680	62/194 (32%)
PSD2	XP_011535998.1	Sec7	317..484	CDD:238100	59/184 (32%)
		PH_EFA6	530..653	CDD:270107	23/132 (17%)
		PH	550..645	CDD:278594	15/104 (14%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165148867
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5307
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740