Protein Alignment garz and iqsec3a

DIOPT Version :9

• Sequence 1: NP_610761.2
• Gene: garz / 36337
• FlyBaseID: FBgn0264560
• Length: 1983
• Species: Drosophila melanogaster
• Sequence 2: XP_009298725.1
• Gene: iqsec3a / 797355
• ZFINID: ZDB-GENE-041210-343
• Length: 1285
• Species: Danio rerio
• Alignment Length: 1108
• Identity: 232/1108 - (20%)
• Similarity: 402/1108 - (36%)
• Gaps: 325/1108 - (29%)

  Fly   236 AQTAPRKSSAV----EEPPQTPQSANLTVPGHLKAPILATTPASPAGNILDMQGKITQTPTTTAS 296
            |..||...|..    |||| .|.|  :..|..:.:|....||.|...:.:.::..:.::..|:.:
Zfish   183 APDAPESDSQACVPSEEPP-LPSS--IATPSPVASPSHGVTPTSAPQSEVQVEHHVAESTVTSIN 244

  Fly   297 TG--------------------------------EDET-TVPETPVIQ-----VESTESEPLLDG 323
            .|                                |::| |.|..|:.:     .|..|.|....|
Zfish   245 EGGGDGDRDGGDAQEKGSAEVEKEEVRAEEIVQEEEKTQTQPPQPIQEEVKKGTEEQEKETPSTG 309

  Fly   324 ETGEATS--------------TLAEANSSEYINSVGVRFTQ-QSTDHDVTS--LSPYGLPFIQEL 371
            .||...|              ..:.:.:|:|..|:.::..| :..:|....  :|......||..
Zfish   310 STGRRASLHHTASPIRVQRNGACSHSTTSDYELSLDLKNKQIEMLEHKYGGHLISRRAACKIQTA 374

  Fly   372 FRFLIILCNPLDKQNS--DSMMHTGLSLLTVAFE----VAAD----------------------N 408
            ||...:..|....:||  :|.:...:||..|..:    ::|:                      .
Zfish   375 FRQYQLSKNFEKIRNSLLESRLPRRISLRKVRVQNTEGISAERALAEGCNLTSIPLVRSPSLPTT 439

  Fly   409 IGKYEGLLELVKDDLCRNLISLLSS--ERLSIFAADLQLCFLLFESLR--GHLKFQLEAYLRK-- 467
            :|   |.|..::|.....:.||..|  :.||.::.. .:|     ||:  |..:|..||:...
Zfish   440 VG---GTLTDLEDSFNEQVQSLAKSIDDALSNWSMK-TMC-----SLQEGGTYQFSSEAFSTAGG 495

  Fly   468 ---LSEIIASDNPKTPYEMRE-----LALDNLLQ-LWRIPGFVTELYINYDCDLY--CTDMFESL 521
               |:|.:...:|..|.....     .:|:|:.| ..::.....::.:..|...:  .:.:.||.
Zfish   496 KSGLAETVKKGSPMDPSTFHSGTGQVDSLENVAQSASKLMMAFRDVTVQIDSQNFRMSSSVMESS 560

  Fly   522 TNLLSKYTLSATNAVYSTHIISMDTLLSVIDSIERNCAASKNSS-----------NNRESLPEA- 574
            |      ::|..|.:....||:.......|:.::......:.|:           .:.|.:|:.
Zfish   561 T------SVSLGNCIQQGAIITESPQQPKINDVKEQPQQRQPSTFLEDPVSPPLEQDAEEVPDGD 619

  Fly   575 APATGGSRH---------SRHNSGLEGIVIDSGNSVAAE-------------------------- 604
            .||...|..         ......:....|.:..::.:|
Zfish   620 FPAPPPSEEVLGEDVLPLELEKQEVPQPTIPAQTAITSETLSPPEVAETPVTPIVEVLEAKHIES 684

  Fly   605 EKVENIASFINASSHRLRLQSGGEGVGITSEQ------------------------LAKVKQKKR 645
            :..:|.:..:::||.....||..|   ::|::                        |:....:||
Zfish   685 DTADNSSEQMSSSSTSTSAQSASE---VSSKEALQAMILSLPRYHCENPTSCKSPTLSTDIMRKR 746

  Fly   646 LLSQGTERFNQRPEKGIQYLQEHGILNAELDPMQVALFLRENPGLDKKMIGEYI-SKKKNVDSKI 709
            |...|...||..|:||:|:|...|.:..  .|:.||.||.:..||.::||||:: :.||..:..:
Zfish   747 LYRIGLNLFNINPDKGLQFLISRGFIPD--TPIGVAHFLLQRKGLSRQMIGEFLGNSKKPFNRDV 809

  Fly   710 LINFVDSFDFTGLRVDQALRLYLETFRLPGEAPLIFLVLEHFSDHWHKQNQD---PFANVDAAFR 771
            |...||..||:|:.:|:|||.:....|:.|||..:..::|.||..:...|.|   .|.|.|..|.
Zfish   810 LDCVVDEMDFSGMELDEALRKFQAHIRVQGEAQKVERLIEAFSQRYCMCNPDIVQQFHNPDTIFI 874

  Fly   772 LAYAIIMLNMDQHNSNAKRLNVPMTLEDFTKNLRGLNGGEDFDQEMLAQVFNAIKNEEIVMPAEQ 836
            ||:|||:||.|.::.|.|. :..|.||||.:||||::.|.|..::|:..::..|:..|
Zfish   875 LAFAIILLNTDMYSPNIKP-DRKMLLEDFIRNLRGVDDGADIPRDMVVGIYERIQLRE------- 931

  Fly   837 TGLVRENYQWKVLLRRGDTHDGHFHYVHDASYDVEIFNIVWGASLSALSFMFD------KSTETG 895
                         ||..:.|..:...|..:...::....|....|...|.:|:      ...:..
Zfish   932 -------------LRSNEDHVTYVTKVEQSIVGMKTVLSVPHRRLVCCSRLFEVTDINKAQKQAA 983

  Fly   896 YQRTLAGFSKSAAI---------SAHYNLHSDFDALVLTLCKFTTLLS---SVEQHEPAP----- 943
            :||.:..|:....|         ||.|           |.||...||.   .:.::|..|
Zfish   984 HQREVFLFNDLLVILKLCPKKKSSAAY-----------TFCKTMGLLGMQFHLFENEYFPHAMTI 1037

  Fly   944 ----ANNETQQAVNFGLNGKAQAAMRTVFLLVHDYGDCLRESWKHILDLYLQLFRLKL-LPKSLI 1003
                :.:|.:|.:||    .||.| ..:...|.|    |:||...:.:  ::..|::. |.|...
Zfish  1038 VSPCSGSEKKQVLNF----CAQNA-EELLKFVED----LKESIAEVSE--MEQIRIEWELEKQQG 1091

  Fly  1004 EVEDFCEANGKAMLILEK---PREKQ-----ESGL-------FSSLYSF------ISSEG----- 1042
            ......::||..:.:..:   |..||     :|||       .:.|.:|      :|.|.
Zfish  1092 AKTHPIKSNGTQLELRGRQGSPSGKQDLNISQSGLNAIEVSIHNRLQTFQLNAAPLSPENAAHLN 1156

  Fly  1043 -QREPTYEEQDFIKLGRK-----------CIKECQLDQMLQESKFVQLESLQELLKCVLALLKAP 1095
             ||||..:.    .|.|.           .:.|.:.|.::|         .|:::| |:.|.|..
Zfish  1157 HQREPIQQP----PLQRASPTTSYSYHPVALTELRPDTLIQ---------CQQIVK-VIVLDKGG 1207

  Fly  1096 QGH 1098
            .||
Zfish  1208 HGH 1210

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
garz	NP_610761.2	COG5307	346..>1062	CDD:227623	190/904 (21%)
		Sec7_N	370..512	CDD:289549	34/184 (18%)
		Sec7	643..830	CDD:279680	71/190 (37%)
iqsec3a	XP_009298725.1	Sec7	744..932	CDD:279680	72/210 (34%)
		IQ_SEC7_PH	957..1084	CDD:293062	31/148 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582820
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930