Protein Alignment garz and Iqsec1

DIOPT Version :10

• Sequence 1: NP_610761.2
• Gene: garz / 36337
• FlyBaseID: FBgn0264560
• Length: 1983
• Species: Drosophila melanogaster
• Sequence 2: XP_038964676.1
• Gene: Iqsec1 / 686590
• RGDID: 1596313
• Length: 1203
• Species: Rattus norvegicus
• Alignment Length: 794
• Identity: 192/794 - (24%)
• Similarity: 302/794 - (38%)
• Gaps: 243/794 - (30%)

  Fly   173 PRL---SELLRRSAE-------KSLKDMVLLFFMRLPQFAEERSDTMLQKRF-----------TI 216
            |||   :.:||:.||       :||.:.     ..|....:::...||::::           ||
  Rat   171 PRLQHSTSVLRKQAEEEAIKRSRSLSES-----YELSSDLQDKQVEMLERKYGGRLVTRHAARTI 230

  Fly   217 GDA-------------ASGATQEKLKRKTVAQAQTAPRKSSAVEEPPQTPQS------ANLT--- 259
            ..|             .|..::.::.|:.|....   |...:.|.|.:...|      .::|
  Rat   231 QTAFRQYQMNKNFERLRSSMSENRMSRRIVLSNM---RMQFSFEGPEKVHSSYFEGKQVSVTNDG 292

  Fly   260 ------VP---GHLKAPIL-ATTPASP-AGNILDMQGKITQTPTTTASTGED--------ETTVP 305
                  ||   |.|..|.| :..|:|. |..|.:::...::...:.|.:.:|        ...||
  Rat   293 SQLGALVPSECGDLSDPALKSPAPSSDFADAITELEDAFSRQVKSLAESIDDALNCRSLHSEEVP 357

  Fly   306 ETPVIQVESTESEPLLDG----ETGEATSTLAEANSSEYINSVGVRFTQQSTDHDVTSLSPYGLP 366
            .:...:...||.:|.|.|    :..|.|::.::.  :.||              |...||| .||
  Rat   358 ASDTARARDTEPKPGLHGMDHRKLDEMTASYSDV--TLYI--------------DEEELSP-PLP 405

  Fly   367 FIQELFRFLIILCNPLDKQNSDSMMHTGLSLLTVAFEVAADNIGKYEGLLELVKDD------LCR 425
            ..|...|       | ....||..:.:|        ..|.|    |..|..  |:|      .||
  Rat   406 LSQAGDR-------P-SSTESDLRLRSG--------GAAQD----YWALAH--KEDKADTDTSCR 448

  Fly   426 NLISLLSSE-RLSIFAADLQLCFLLFE------------SLRGHLKFQLEAYLRKLSEIIASDN- 476
            :..||...| ||.:    ..|..|..|            |.|..||.| .||.|.|.....|..
  Rat   449 STPSLERPEPRLRV----EHLPLLTIEPPSDSSVELSDRSDRSSLKRQ-SAYERSLGGQQGSPKH 508

  Fly   477 ------PK-TPYEMRELALDNLLQLWRIP-GFVTELYINYDCDLYCTDMFESLTNLLSK----YT 529
                  || .|.|..||..       |.| ...:.|.||            ...|..||    |:
  Rat   509 GPHGGPPKGLPREEPELRP-------RPPRPLESHLAIN------------GSANRQSKSESDYS 554

  Fly   530 LSATNAVYSTHIISMDTLLSVIDSIERNCAASKNSSNNRESLPEAAPATGGSRHSRHNSGLEGIV 594
            ....:::.||. .|.||:         ||:   :.|::|:||.|..
  Rat   555 DGDNDSINSTS-NSNDTI---------NCS---SESSSRDSLREQT------------------- 587

  Fly   595 IDSGNSVAAEEKVENIASFINASSHRLRLQSGGEGVGITSEQLAKVKQKKRLLSQGTERFNQRPE 659
                               ::..::....::..:....:::.:     :||....|...||::||
  Rat   588 -------------------LSKQTYHKETRNSWDSPAFSNDVI-----RKRHYRIGLNLFNKKPE 628

  Fly   660 KGIQYLQEHGILNAELDPMQVALFLRENPGLDKKMIGEYI-SKKKNVDSKILINFVDSFDFTGLR 723
            ||||||.|.|.:..  .|:.||.||.:..||.::||||:: :::|..:..:|...||..||:.:.
  Rat   629 KGIQYLIERGFVPD--TPVGVAHFLLQRKGLSRQMIGEFLGNRQKQFNRDVLDCVVDEMDFSAME 691

  Fly   724 VDQALRLYLETFRLPGEAPLIFLVLEHFSDHWHKQNQD---PFANVDAAFRLAYAIIMLNMDQHN 785
            :|:|||.:....|:.|||..:..::|.||..:...|..   .|.|.|..|.||:|||:||.|.::
  Rat   692 LDEALRKFQAHIRVQGEAQKVERLIEAFSQRYCVCNPGVVRQFRNPDTIFILAFAIILLNTDMYS 756

  Fly   786 SNAKRLNVP---MTLEDFTKNLRGLNGGEDFDQEMLAQVFNAIKNEEIVMPAEQTGLVRENYQWK 847
            .|.|    |   |.||||.|||||::.|||..:|.|..::..|:..|:....:....|::  ..|
  Rat   757 PNVK----PERKMKLEDFVKNLRGVDDGEDIPRETLIGIYERIRKRELKTNEDHVSQVQK--VEK 815

  Fly   848 VLLRR---GDTHDG 858
            :::.:   |..|.|
  Rat   816 LIVGKKPIGSLHHG 829

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
garz	NP_610761.2	PLN03076	<395..>986	CDD:215560	134/506 (26%)
		Sec7	643..830	CDD:460178	75/193 (39%)
Iqsec1	XP_038964676.1	Sec7	612..800	CDD:460178	75/193 (39%)
		IQ_SEC7_PH	832..961	CDD:465120