Protein Alignment garz and Iqsec2

DIOPT Version :10

• Sequence 1: NP_610761.2
• Gene: garz / 36337
• FlyBaseID: FBgn0264560
• Length: 1983
• Species: Drosophila melanogaster
• Sequence 2: NP_001264354.2
• Gene: Iqsec2 / 685244
• RGDID: 1596452
• Length: 1488
• Species: Rattus norvegicus
• Alignment Length: 614
• Identity: 140/614 - (22%)
• Similarity: 233/614 - (37%)
• Gaps: 206/614 - (33%)

  Fly   557 NCAASKNSSNNRESLPEAAPATG-----GSRHSRHNSGLEGIVIDSGNSVAAEEKVENIASFINA 616
            ||:   :.|::|:||.| .||||     ..|.:||          |.:|.|....|      :..
  Rat   710 NCS---SGSSSRDSLRE-PPATGLCKQTYQRETRH----------SWDSPAFNNDV------VQR 754

  Fly   617 SSHRLRLQSGGEGVGITSEQLAKVKQKKRLLSQGTERFNQRPEKGIQYLQEHGILNAELDPMQVA 681
            ..:|:                            |...||::||||||||.|.|.|:.  .|:.||
  Rat   755 RHYRI----------------------------GLNLFNKKPEKGIQYLIERGFLSD--TPVGVA 789

  Fly   682 LFLRENPGLDKKMIGEYI-SKKKNVDSKILINFVDSFDFTGLRVDQALRLYLETFRLPGEAPLIF 745
            .|:.|..||.::||||:: :::|..:..:|...||..||:.:.:|.|||.:....|:.|||..:.
  Rat   790 HFILERKGLSRQMIGEFLGNRQKQFNRDVLDCVVDEMDFSSMDLDDALRKFQSHIRVQGEAQKVE 854

  Fly   746 LVLEHFSDHWHKQNQ---DPFANVDAAFRLAYAIIMLNMDQHNSNAKRLNVPMTLEDFTKNLRGL 807
            .::|.||..:...|.   ..|.|.|..|.||:|||:||.|.::.:.| ....|.|:||.|||||:
  Rat   855 RLIEAFSQRYCVCNPALVRQFRNPDTIFILAFAIILLNTDMYSPSVK-AERKMKLDDFIKNLRGV 918

  Fly   808 NGGEDFDQEMLAQVFNAIKNEEIVMPAEQTGLVRENYQWKVLLRRGDTHDGHFHYVHDASYDVEI 872
            :.|||..:::|..::..|:..|:                       .|:|.|...|.
  Rat   919 DNGEDIPRDLLVGIYQRIQGREL-----------------------RTNDDHVSQVQ-------- 952

  Fly   873 FNIVWGASLSALSFMFDKSTETGYQRTLAGFSKSAAISAHYNLHSDFDALVLTLCKFTTLLSSVE 937
                                  ..:|.:.|  |...:|..:.                .|:...:
  Rat   953 ----------------------AVERMIVG--KKPVLSLPHR----------------RLVCCCQ 977

  Fly   938 QHEPAPANNETQQAVNFGLNGKAQAAMRTVFLLVHDYGDCL-----------------RESWKHI 985
            .:| .|..|..|:   .||:      .|.|||    :.|.|                 |:|:. :
  Rat   978 LYE-VPDPNRPQR---LGLH------QREVFL----FNDLLVVTKIFQKKKILVTYSFRQSFP-L 1027

  Fly   986 LDLYLQLFR-------LKLLP-----------------------------KSLIEVEDFCEANGK 1014
            :::::|||:       :|||.                             :|:.||::..:...:
  Rat  1028 VEMHMQLFQNSYYQFGIKLLSAVPGGERKVLIIFNAPSLQDRLRFTSDLRESIAEVQEMEKYRVE 1092

  Fly  1015 AMLILEK----PREKQESGLFSSLYSFISSEGQREPTYEEQDFIKLGRKCIKECQLDQMLQESKF 1075
            :.|..:|    |...|..|...|:...: :....|.||...|.:|.|........|....:..:.
  Rat  1093 SELEKQKGMMRPNASQPGGAKDSVNGTL-ARSSLEDTYGAGDGLKRGALSSSLRDLSDAGKRGRR 1156

  Fly  1076 VQLESLQELLKCVLALLKAPQGHKSIGLP 1104
            ..:.||...::.  :::.:|:.|:.:..|
  Rat  1157 NSVGSLDSTIEG--SVISSPRPHQRMPPP 1183

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
garz	NP_610761.2	PLN03076	<395..>986	CDD:215560	113/454 (25%)
		Sec7	643..830	CDD:460178	70/190 (37%)
Iqsec2	NP_001264354.2	GAS	26..>146	CDD:464001
		Sec7	753..941	CDD:460178	71/218 (33%)
		IQ_SEC7_PH	963..1092	CDD:465120	25/159 (16%)
		KLF1_2_4_N	<1318..1425	CDD:425360