DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment garz and cyth4a

DIOPT Version :9

Sequence 1:	NP_610761.2	Gene:	garz / 36337	FlyBaseID:	FBgn0264560	Length:	1983	Species:	Drosophila melanogaster
Sequence 2:	XP_695228.4	Gene:	cyth4a / 566849	ZFINID:	ZDB-GENE-090624-6	Length:	411	Species:	Danio rerio

Alignment Length:	328	Identity:	97/328 - (29%)
Similarity:	159/328 - (48%)	Gaps:	43/328 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   558 CAASKNSSNNRES-LPEAAPATGGSRHSRHNSGLEGIVIDSGNSVAAEEKVENIASFINASSHRL 621
            |:.:...:..::| |...||::..:...:.....:.:::|....:..|  :||:.:.|..
Zfish     5 CSTATMGTQRKDSFLWGKAPSSFNANDKKQTEVHKHVILDDIKQLRME--IENMMTEIQT----- 62

  Fly   622 RLQSGGEGVGITSEQLAKVKQKKRLLSQGTERFNQRPEKGIQYLQEHGILNAELDPMQVALFLRE 686
             :::..|...:         .|.:.:..|.::||..|:||||||.::|:|  ...|..||.||.:
Zfish    63 -MEADDENKNV---------MKNKRIQCGKKKFNMDPKKGIQYLVDNGLL--AWKPESVAEFLYK 115

  Fly   687 NPGLDKKMIGEYISKKKNVDSKILINFVDSFDFTGLRVDQALRLYLETFRLPGEAPLIFLVLEHF 751
            ..||:|..||.::.:::.:..:||..||...:|:.|.:.||||.:|.:|||||||..|..::|.|
Zfish   116 EEGLNKTAIGNFLGEREEIHLQILQAFVHLHEFSNLNLVQALRQFLWSFRLPGEAQKIDRMMEAF 180

  Fly   752 SDHWHKQNQDPFANVDAAFRLAYAIIMLNMDQHNSNAKRLNVPMTLEDFTKNLRGLNGGEDFDQE 816
            :..:...|...|.:.|..:.|::||||||...||.|.|.   ..|||.|....||:|.|.|...|
Zfish   181 AQRYCTCNTGVFQSTDTCYILSFAIIMLNTSLHNPNVKD---KTTLERFISMNRGINNGGDLPSE 242

  Fly   817 MLAQVFNAIKNEEIVMPAEQTG---------------LVRENYQWKVLLRRG-DTHDG---HFHY 862
            :|.:::.:||||...:| |..|               |::|..:.|...||. ...||   :|.|
Zfish   243 LLEKLYESIKNEPFKIP-EDDGNDLTHTFFNPDREGWLLKEGGRIKTWKRRWFILTDGCLYYFQY 306

  Fly   863 VHD 865
            ..|
Zfish   307 TTD 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
garz	NP_610761.2	COG5307	346..>1062	CDD:227623	97/328 (30%)
		Sec7_N	370..512	CDD:289549
		Sec7	643..830	CDD:279680	73/186 (39%)
cyth4a	XP_695228.4	Sec7	74..256	CDD:279680	73/186 (39%)
		PH_GRP1-like	271..390	CDD:269954	10/39 (26%)
		PH	275..387	CDD:278594	10/35 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582813
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5307
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740