Protein Alignment garz and iqsec3b

DIOPT Version :9

• Sequence 1: NP_610761.2
• Gene: garz / 36337
• FlyBaseID: FBgn0264560
• Length: 1983
• Species: Drosophila melanogaster
• Sequence 2: XP_682922.4
• Gene: iqsec3b / 555340
• ZFINID: ZDB-GENE-050420-210
• Length: 1051
• Species: Danio rerio
• Alignment Length: 1109
• Identity: 251/1109 - (22%)
• Similarity: 408/1109 - (36%)
• Gaps: 304/1109 - (27%)

  Fly   175 LSELLRRSAEKSLKDMVLLFFMRLPQFAEERSDTMLQKRFTIG-------DAASGATQEKLKRKT 232
            :|.||....:      .:|:...|....:.:...:..:|:.|.       |.   ||:.:..|.:
Zfish     1 MSSLLENPLQ------AVLYLKELTAIVQNQQSLIQTQRYRIDILERRLEDL---ATENRQLRDS 56

  Fly   233 VAQAQTAPRKSSAVEEPPQTPQSANLTVPGHLKA---PILATTPASPAGNI--LDMQ----GKIT 288
            .:..:..||     ..||..|::::|  |...:|   |:...||......|  ||||    |..|
Zfish    57 GSHHRHPPR-----YHPPPPPRTSSL--PRTSRAETPPVQNQTPQQQQQQISPLDMQLVPAGPST 114

  Fly   289 QTPTTTASTGEDE--------TTVPETP------VIQVESTESEPLL--------DGETGEATST 331
            .:|.   |..|||        :.||:||      |....::||:.:|        :...||:::|
Zfish   115 ASPD---SADEDEELQDPCCRSLVPQTPATLCRAVGLPRASESQTVLHQFCCPAPEAPEGESSTT 176

  Fly   332 LAEANSSEYINSVGVRFTQQSTDH--DVT--------SLSP-------------YGLPF------ 367
                 .|..:.:.|....::..|.  ||.        .|||             ||.|.
Zfish   177 -----CSSSVPAAGEEQKEEKRDDQPDVPPCSHPPEYELSPDLKQKQIEELEQKYGGPLISRRAA 236

  Fly   368 --IQELFRFLIILCNPLDKQNS--DSMMHTGLSLLTVAFEVAADNIGKYEGLLELVKDDLCRNL- 427
              ||..||...:..|....:||  :|.:...:|:..|  .|..|.......|:|     .|..:
Zfish   237 CKIQTAFRQYQLSKNFQKIRNSVLESGIPRRMSVRRV--RVQRDGFSAERALME-----GCSIMG 294

  Fly   428 ISLLSSERLSIFAADLQLCFLLFESLRGHLKFQLEAYLRKLSEIIAS------------------ 474
            |.|..|..|.:...      .....|......|:::..|.:.|.::|
Zfish   295 IPLTHSTSLPVTTT------TTLTHLEDTFSEQVQSLARSIDEALSSWSTIRDGEGEKSSAAPPS 353

  Fly   475 -DNPK----TPYEMREL-----------ALDNLLQLWRIPGFVTELYINYDCDLYCTDMFE--SL 521
             .:|:    .|..::|.           :...|:..:|   .||....|::..| .:.|.|  ||
Zfish   354 GSHPEGLLMDPSSLQEATQSGCGESIPRSASKLMMAFR---DVTVQIDNHNFRL-SSSMLESVSL 414

  Fly   522 TNLLSKYTLSATNAVYSTHIISMDTLLSVIDSIERNCAASKNSSNNRESLPEAAPATGGSRHSRH 586
            .|.::|.|:|...  ....|....||.:..|........|:....|::.:......||
Zfish   415 GNGVAKETVSEPQ--IGGQIAGQTTLSTAGDPEFPPPPPSEEEKENQQPIGLDTVTTG------- 470

  Fly   587 NSGLEGIVIDSGNSVAAEEKVENIASFINASSHRL-----------RLQSGGEGVGITSEQLAKV 640
             :||||   ...|.| |.|..||.:..|::||...           |........|..|..:|
Zfish   471 -AGLEG---KQTNQV-APEIAENSSDPISSSSTSTSACETMILSLPRPHCQNTPCGTLSTDIA-- 528

  Fly   641 KQKKRLLSQGTERFNQRPEKGIQYLQEHGILNAELDP---MQVALFLRENPGLDKKMIGEYI-SK 701
              :|||...|...||..|:||||:|...|.:     |   :.||.||.:..||.::||||:: :.
Zfish   529 --RKRLYRIGLNLFNVNPDKGIQFLISRGFI-----PDTAIGVAHFLLQRKGLSRQMIGEFLGNS 586

  Fly   702 KKNVDSKILINFVDSFDFTGLRVDQALRLYLETFRLPGEAPLIFLVLEHFSDHWHKQNQD---PF 763
            |:..:..:|...||..||:.|.:|:|||.:....|:.|||..:..::|.||..:...|.|   .|
Zfish   587 KRQFNRDVLDCVVDEMDFSMLELDEALRKFQAHVRVQGEAQKVERLIEAFSQRYCMCNPDVVQQF 651

  Fly   764 ANVDAAFRLAYAIIMLNMDQHNSNAKRLNVP---MTLEDFTKNLRGLNGGEDFDQEMLAQVFNAI 825
            .|.|..|.||:||::||.|.::.|.|    |   |.||||.:||||::.|.|..:||||.::..|
Zfish   652 HNPDTIFILAFAIVLLNTDMYSPNIK----PERKMLLEDFIRNLRGVDDGADIPREMLAGIYERI 712

  Fly   826 KNEEIVMPAEQTGLVRENYQWKVLLRRGDTHDGHFHYVHDASYDVEIFNIVWGASLSALSFMFD- 889
            :..|                    ||..:.|..:...|..:...::....|....|...|.:::
Zfish   713 QQRE--------------------LRSNEDHVTYVTRVEQSILGMKTILSVPHRRLVCCSRLYEV 757

  Fly   890 -----KSTETGYQRTLAGFS------------KSAAISAHYNLHSDFDALVLTLCKFTTLLSS-- 935
                 ...:..:||.:..|:            |:||              ..|.||...||..
Zfish   758 TDVNKPQKQASHQREVFLFNDLIVILKLCPKKKTAA--------------TYTFCKAMGLLGMQF 808

  Fly   936 ---VEQHEP------APANNETQQAVNFGLNGKAQAAMRTVFLLVHDYGDCLRESWKHILDLYLQ 991
               ..::.|      :|.::|.:|.|:| .:..|...::.:        :.||||...:.:  ::
Zfish   809 HLFENEYYPHGITILSPFSSEKKQVVSF-CSQSADELLKFI--------EDLRESIAEVAE--ME 862

  Fly   992 LFRLKLLPKSLIEVEDFCEANGKAMLILEKPREKQESGLFSSLYSFISSEGQREPTYEEQDFIKL 1056
            ..|::...:....|.:....||..:.|...|                 |....:..||     |.
Zfish   863 QIRIEWELERQQVVRNQTNKNGTQLDIHAGP-----------------SSASGDDFYE-----KA 905

  Fly  1057 GRKCIKECQLDQMLQE---SKFVQLESLQELLKCVLALLKAPQGHKSIGLPYAEDQTVFWMEFLV 1118
            |...: |..:...||.   |..:...|.|:.    ||:|.:|....::.:   ...|:...:.:|
Zfish   906 GSNTV-EVSIHNRLQTYQLSSPLAPPSAQQR----LAVLPSPAPDSALTI---SPDTLIQCQQIV 962

  Fly  1119 KIVV 1122
            |::|
Zfish   963 KVIV 966

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
garz	NP_610761.2	COG5307	346..>1062	CDD:227623	190/835 (23%)
		Sec7_N	370..512	CDD:289549	30/178 (17%)
		Sec7	643..830	CDD:279680	74/196 (38%)
iqsec3b	XP_682922.4	Sec7	529..717	CDD:279680	75/216 (35%)
		IQ_SEC7_PH	742..868	CDD:293062	26/150 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582821
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930