Protein Alignment garz and Psd3

DIOPT Version :10

• Sequence 1: NP_610761.2
• Gene: garz / 36337
• FlyBaseID: FBgn0264560
• Length: 1983
• Species: Drosophila melanogaster
• Sequence 2: XP_006253101.1
• Gene: Psd3 / 306380
• RGDID: 1559968
• Length: 1296
• Species: Rattus norvegicus
• Alignment Length: 1223
• Identity: 237/1223 - (19%)
• Similarity: 399/1223 - (32%)
• Gaps: 377/1223 - (30%)

  Fly    75 RTADAT--GPLTSLALASVNKLLSYGLI-------------DPTSP----------NLADIVERI 114
            :|.||:  |..|.|.....|:...||.:             |..||          :|....:.:
  Rat   292 KTPDASDHGGSTLLPPTVTNEFPEYGTMEEGAEGLRASLDFDAKSPPCHLPGQQAVHLLAGQDSV 356

  Fly   115 ADAVTHARFMGTDQSSDGVTFMRVIEVLHTLIRSPEGAAVSNVSMCEVML------SCFKISFEP 173
            .::||... .|..|.......::.|:.|.:.:::.|....|.......:|      |..::..||
  Rat   357 LNSVTEGP-NGAPQCHPQEQSLQPIDSLISALKATEARIASGTFQATKVLDKDANFSVHRVDKEP 420

  Fly   174 RLSELLRRSAEKSLKDMVLLFFMRLPQFAEERSDTMLQKRFTIGDAASGATQEKLKRKTVAQAQT 238
            |.:.                   ..||.|        .:.|.:|...|.      .|....:..|
  Rat   421 RTAS-------------------HKPQRA--------HRTFPVGPGKSP------DRPLSVEVPT 452

  Fly   239 APRKSSAVEE------PPQTP----QSANLTVPGHLKAPILATTPASPAG----NILDMQGKITQ 289
            ..:.|..::|      |.:||    |..|....|.|..|..| .|.|...    |.:|..|.:..
  Rat   453 EEKFSLHIQEDLTALLPEETPAQLSQITNYRRQGPLHVPESA-CPVSLGSAKNHNSVDRIGALKD 516

  Fly   290 TPTTTAS------------------------------TGED-ETTVP---ETPVIQVESTESEPL 320
            ..:....                              |||: |:..|   |||..:..|...:..
  Rat   517 QKSDLGRENPRGCDRGGSMGRQTRIKHVEFQGVEILWTGEEVESRHPAGFETPPERTASPVRKEF 581

  Fly   321 LDGETGEATSTLAEANSSEYINSVGVRFTQQSTDHDVTSLSPYGLPFIQELFRFLIILCNPLDKQ 385
            ..|.:..:::|.|.::|:....||.          |.|...|...|
  Rat   582 AKGPSHSSSATGACSSSTHLTGSVS----------DETCKEPSARP------------------- 617

  Fly   386 NSDSMMHTGLSLLTVAFEVAADNIGKYEGLLELVKDDLCRNLISLLSSERLSIFAADLQLCFLLF 450
                    |.||.|:: .|.....|:.:..|...|:.|..|.......||.
  Rat   618 --------GTSLGTLS-PVPLGESGEDDVFLRESKEHLEENFDIQGDKERF-------------- 659

  Fly   451 ESLRGHLKFQLEAYLRKLSEIIASDNPKTPYEMRELALDNLLQLWRIPGFVTELYINYDCDLYCT 515
                    |:.|.:||      ..|             |::|.    ||:..:     ..|:| :
  Rat   660 --------FKQEEHLR------GGD-------------DDILG----PGYTED-----STDVY-S 687

  Fly   516 DMFESLTNLLSKYTLSATNAVYSTHIISMDTLLSVIDS----------------------IERNC 558
            ..||::        |..|:..||..  |::||.|..||                      :||.
  Rat   688 SQFETI--------LDNTSLYYSAE--SLETLYSEPDSYFSFEMPLTPMIQQRIKEGGQFLERT- 741

  Fly   559 AASKNSSNNRESLPEAAPATGGSRHSRHNSGLEGIVIDSGNSVAAEEKVENIASFINASSH---- 619
                :...:.:.|  :..|.||.... :::|:...:.|..|||......|  .:|..:|.:
  Rat   742 ----SVGGHHDVL--SVSADGGIVMG-YSTGITNGLHDPSNSVYTRGPQE--IAFWGSSGYCFDK 797

  Fly   620 --RLRLQSGGEGVGITSEQLAKVKQKKRLLSQGTE---RFNQRPEKGIQYLQEHGILNAELDPMQ 679
              ..||....|   :.|.::.: |:....||.||.   ...:|..|.:.:|..
  Rat   798 GKPTRLDGNSE---MGSTEILE-KETTENLSNGTNSNVEAAKRLAKRLYHLDR------------ 846

  Fly   680 VALFLRENPGLDKKMIGEYISKKKNVDSKILINFVDSFDFTGLRVDQALRLYLETFRLPGEAPLI 744
               |.|.:       :.:::.|.......:...::..|||||:.:||:||.:|:.|.|.||....
  Rat   847 ---FKRSD-------VAKHLGKNNEFSKLVAEEYLKFFDFTGMTLDQSLRYFLKAFSLVGETQER 901

  Fly   745 FLVLEHFSDHWHKQNQDPFANVDAAFRLAYAIIMLNMDQHNSNAKRLNVPMTLEDFTKNLRGLNG 809
            ..:|.|||:.:...|.|...:.|....|..|:::||.|.|..|   :...||.::|..||:|:|.
  Rat   902 ERILIHFSNRYFSCNPDTITSKDGVHCLTCALMLLNTDLHGHN---IGKKMTCQEFITNLQGVNE 963

  Fly   810 GEDFDQEMLAQVFNAIKNEEI----------VMPAEQTGLVRENYQWKVLLRRGDTHDGHFHYVH 864
            |.||.:::|..::|:||||::          ..|:|.|.........|.:.|.|.|.:......|
  Rat   964 GGDFSKDLLKALYNSIKNEKLEWAADDEEKKKSPSEGTDEKANGTHPKTISRIGSTTNPFLDIPH 1028

  Fly   865 DASYDVEIFNIVWGASLSALSFMFDKSTETGYQRTLAGFSKSAAISAHYNLHSDFDA-------- 921
            |.:                                 |...||..::.  .:|:|.|.
  Rat  1029 DPN---------------------------------AAVYKSGFLAR--KIHADMDGKKTPRGKR 1058

  Fly   922 ---LVLTLCKFTTLLSSVEQHEPAPANNE----TQQAVNFGLNGKAQAAMR--TVF--------- 968
               ....:.|.|.|....::::|..:.::    ...:|:..|..||....:  .||
  Rat  1059 GWKTFYAVLKGTVLYLQKDEYKPEKSLSDEDLKNAVSVHHALASKATEYEKKPNVFKLKTADWRV 1123

  Fly   969 LLVHDYGDCLRESWKHILDLYLQLFRLKLLPKSLIEVEDFCEANGKAMLILEKPREKQESGLFS- 1032
            ||.........:.|.:.::....:|.....|.::...:.|    .:.:|.....:..||..|.|
  Rat  1124 LLFQTQSPEEMQGWINKINCVAAVFSAPPFPAAIGSQKKF----SRPLLPATTTKLSQEEQLKSH 1184

  Fly  1033 -SLYSFISSEGQREPTYEEQDFIKLGRKCIKECQLDQMLQESKFVQLESLQELLKCVLALLKAPQ 1096
             |....|::|.....:|.....:|  .|.:.|.:|.....:.:..:.|....:||.....|.:.:
  Rat  1185 ESKLKQITTELAEHRSYPPDKKVK--AKDVDEYKLKDHYLDFEKTRYEIYVSILKEGGKDLLSTE 1247

  Fly  1097 GHKSIGL----------PYAEDQTVFWMEFLVKIVVHNRDRMIPLWPAVRDQM 1139
            |::.:||          |.|...|.     .||..|..|....|..|.::.::
  Rat  1248 GNEPVGLKKSHSSPSLNPDASPVTA-----KVKRNVSERKDHRPETPGIKQKV 1295

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
garz	NP_610761.2	PLN03076	<395..>986	CDD:215560	135/657 (21%)
		Sec7	643..830	CDD:460178	54/189 (29%)
Psd3	XP_006253101.1	Sec7	830..984	CDD:238100	50/178 (28%)
		PH_EFA6	1029..1154	CDD:270107	21/159 (13%)