Protein Alignment garz and sec74

DIOPT Version :10

• Sequence 1: NP_610761.2
• Gene: garz / 36337
• FlyBaseID: FBgn0264560
• Length: 1983
• Species: Drosophila melanogaster
• Sequence 2: NP_594894.2
• Gene: sec74 / 2542073
• PomBaseID: SPAC26F1.01
• Length: 928
• Species: Schizosaccharomyces pombe
• Alignment Length: 772
• Identity: 129/772 - (16%)
• Similarity: 244/772 - (31%)
• Gaps: 260/772 - (33%)

  Fly   526 SKYTLSATNAVYSTHIISMDTLLSVIDSIERNCAASKNSSNNRESLPEAAPAT----------GG 580
            |...||..:.::|::....|:.|               |..:..::.|.|.:|          |.
pombe   154 SSIFLSNWSTIFSSNASPTDSQL---------------SPTHTSTIAELAASTLSIFPSGSYAGS 203

  Fly   581 SRHSRHNSGLEGIVIDSGNSVAAEEKVENIASFINASSHRLRLQSGGEGVGITSEQLAKVKQKKR 645
            :..|...|.     |||...:...:.|.:::|..:|.:......|..|..|....  ...|....
pombe   204 TFGSPSRSS-----IDSSTYLPRSKSVNSLSSNFSARTPASNQSSVSEDFGAAPN--CDHKHNSV 261

  Fly   646 LLSQGTERFNQRPEKGIQYLQEHGILNAELDPMQV--------ALFLRENPGLDKKMIGEYISKK 702
            .||          :..:..:.:|..:...|:.::.        |:..:....|.|..:.:|:|
pombe   262 TLS----------DFALPDIDQHDTVETILEKVEFTIPKQFTPAILSQGTSSLLKLCLRKYLS-- 314

  Fly   703 KNVDSKILINFVDSFDFTGLRVDQALRLYLETFRLPGEAPLIFLVLEHFSDHWHKQNQDPFANVD 767
                   ::|      |..:.:|.|||.:|..:.||.|...|..||..|||.:...|.|.:.:.|
pombe   315 -------VVN------FKCISLDMALRKFLAVYVLPNETQQIDRVLSTFSDQYFHCNPDLYDSSD 366

  Fly   768 AAFRLAYAIIMLNMDQHN-SNAKRLN-------------VPMTLEDFTKNL-------------- 804
            ..:.|.:::::|:.|..| .|.:::.             :|..||.|..|:
pombe   367 ECYILTFSLMILHTDFFNIHNRQKMTRAEFISNTNLPTILPEILECFYDNITYTPFVHVEHIGCV 431

  Fly   805 ------------------------RGLNGGEDFDQEMLAQVFNAIKNEEIVMPAEQTGLVRENYQ 845
                                    |.....|...|.:..|:.....|.:.::..::...||.:.:
pombe   432 VTSPSNEKPSLSQRLGDSQFRLTKRNTFATESDHQALQEQLTGFRINLDSILDLKKIDSVRTSIE 496

  Fly   846 ------------------WKVLLRRGDTHDGHFHY--------VHDASYDVEIF----------- 873
                              .:::..|.......:|:        .:.|..:|::|
pombe   497 SPTRTADDLYKEFARAPFLQIVSHRSQPQAFSYHFEPSAESESTNPAIINVKVFKLGILIQNEKV 561

  Fly   874 -------NIVWGASLSALSFMFDKSTE--TGYQRTLAGFSKS------------AAISAHYNL-- 915
                   |...|..|::...||.|:..  :|....|..|.:|            .::||.|.:
pombe   562 RKDRLLSNREVGVILTSSQLMFFKNVYWISGLLDQLEDFKRSHSFSPCYFSPHLTSLSADYIIPL 626

  Fly   916 -----HSDFDALVLTLCKFTTLLSSVEQHEPAPAN----NETQQAVNFGLNGKAQAAMRTVFLLV 971
                 :.|...:...|..|:....:...|..:..|    |:....:||      .:...|..|..
pombe   627 SDLVAYGDGSRIENELYSFSVKQKNQRTHVFSVTNVDELNDWLVKINF------VSTFATAGLAP 685

  Fly   972 HDYGDCLRESWKHILDLYLQLFRLKLLPKSLIEVEDFCEANGKA---------------MLILEK 1021
            .:...|:..|.|.|          |.....|.::.:..:|..||               :.|::.
pombe   686 RERLPCVESSDKSI----------KASVSVLPDIYEDSDAMSKASKETRSEVLECSKVRVYIVQN 740

  Fly  1022 PREKQESGLFSSLYSFISSEGQREPTYEEQDF--------------IKLGR--KCIKECQLDQML 1070
            ...|.|..|         .:|:.:.|.:.::.              |:|.|  ..:|:..|.||:
pombe   741 RIYKLEEAL---------RQGESKMTVQRRNAANILHLEPIQSRTRIRLARCSNTLKKNMLAQMI 796

  Fly  1071 QESKF----------VQLES-LQELLKCVLALLKAPQGHKSIGLPYAEDQTVFWMEF 1116
            :..||          ::::| ||:.|:.|..       ...:|...|.:.|:....|
pombe   797 EIQKFKISIKFLKEDLEMDSHLQDYLRSVFP-------SSVMGKENASEDTILESNF 846

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
garz	NP_610761.2	PLN03076	<395..>986	CDD:215560	99/598 (17%)
		Sec7	643..830	CDD:460178	43/246 (17%)
sec74	NP_594894.2	Sec7	<306..422	CDD:460178	32/130 (25%)
		PH	549..676	CDD:214574	22/132 (17%)