Protein Alignment garz and SPBC211.03c

DIOPT Version :9

• Sequence 1: NP_610761.2
• Gene: garz / 36337
• FlyBaseID: FBgn0264560
• Length: 1983
• Species: Drosophila melanogaster
• Sequence 2: NP_596613.1
• Gene: SPBC211.03c / 2540746
• PomBaseID: SPBC211.03c
• Length: 1462
• Species: Schizosaccharomyces pombe
• Alignment Length: 1836
• Identity: 426/1836 - (23%)
• Similarity: 711/1836 - (38%)
• Gaps: 558/1836 - (30%)

  Fly    10 VVRGEMATLMTAMRRGTRWNATA-------------YVDDENDS---------------LLKLFI 46
            :|..|:.|::||:|:.|||..:.             ::.|..:|               |:..|.
pombe    21 LVINEIITVVTAIRKTTRWRNSGVASILGVSTLKDEFLADGLESRWKTNGEKSSSIRYPLVMEFS 85

  Fly    47 DLKHELNRIEDLRQIEPQVFLAPFLEVIRTADATGPLTSLALASVNKLLSYGLIDPTSPNLADIV 111
            .||.:|.....|...:....|:|||..|::...||.:|||.|:::.|..|:.:|...|||||..:
pombe    86 QLKEDLTNRASLNGYDSLKLLSPFLRTIKSPRMTGYITSLCLSAILKFFSFRIISEESPNLALSM 150

  Fly   112 ERIADAVTHARFMGTDQSSDGVTFMRVIEVLHTLIRSPEGAAVSNVSMCEVMLSCFKISFEPRLS 176
            ..::.|:|..||...|.|.|....:||..::..|:|.|..|.:|:.|:||::.:...:..:.|||
pombe   151 RNLSFAITQCRFESFDASQDEAVLLRVSRLMEELLRGPGKAVLSDDSICEIVETGLSMCCQSRLS 215

  Fly   177 ELLRRSAEKSLKDMVLLFFMRLPQFAEERSDTMLQKRFTIGDAASGATQEKLKRKTVAQAQTAPR 241
            ::||.|||.|:                   .::|:|.|           |:||
pombe   216 QVLRYSAELSM-------------------TSILEKIF-----------ERLK------------ 238

  Fly   242 KSSAVEEPPQTPQSANLTVPGHLKAPILATTPASPAGNILDMQGKITQTPTTTASTGEDETTVPE 306
                                                  .:|::
pombe   239 --------------------------------------YIDVK---------------------- 243

  Fly   307 TPVIQVESTESEPLLDGETGEATSTLAEANSSEYINSVGVRF-TQQSTDHDVTS--LSPYGLPFI 368
                    |:||...|              :||..:..|..| .::.|:.|..|  :.|:|:..|
pombe   244 --------TDSEDFWD--------------ASEEHSIKGEEFHYKKITEGDEISNEIDPFGIGSI 286

  Fly   369 QELFRFLIILCNPLDKQNSDSMMHTGLSLLTVAFEVAADNIGKYEGLLELVKDDLCRNLISLLSS 433
            :|:||.|:...:...::.||::....|..:..|.||:..:|..:..|..|:.|.||::|:.|:.|
pombe   287 REVFRVLVSFIDFGKQKFSDNIKAMALRFINTALEVSGSHISDFPSLRVLITDTLCKSLLQLIRS 351

  Fly   434 ERLSIFAADLQLCFLLFESLRGHLKFQLEAYLR-----------------------------KLS 469
            :..::....|.:...|.:::.|.||.|.|.::.                             .||
pombe   352 DHTALLTNSLLVMTTLLQAMPGSLKLQQELFISYLISCLHIPSTTPRERNVETSLHKVVSSLDLS 416

  Fly   470 EII----------------ASDNPKTPYEMRELALDNLLQLWRIPGFVTELYINYDCDLYCTDMF 518
            |.|                |.|....|.|:|||.::.|..|.|||.|:.:||:|||||...:|:.
pombe   417 EEISPDRATPTSFTERKRFAFDTRNRPPEVRELIVECLGSLSRIPYFLIDLYVNYDCDPQMSDLA 481

  Fly   519 ESLTNLLSKYTLSATNAVYSTHII---SMDTLLSVIDSIERNCAASKNSSNNRESLPEAAPATGG 580
            ..|..:|::..| ..:|.|||..:   .:|.||:.|.....:.....|..||...
pombe   482 IDLLKVLTRNCL-VDSARYSTANVPPLCLDALLNFIYYFHEHLQPCYNDPNNTFK---------- 535

  Fly   581 SRHSRHNSGLEGIVIDSGNSVAAEEKVENIASFINASSHRLRLQSGGEGVGITSEQLAKVKQKKR 645
                                       :::|                       :.|.:.|::|.
pombe   536 ---------------------------DDVA-----------------------KTLIESKKRKA 550

  Fly   646 LLSQGTERFNQRPEKGIQYLQEHGILNAELDPMQVALFLRENPGLDKKMIGEYISKKKNVDSKIL 710
            ::.:|.|.||:.|..||.:|.:|.|:....:|..:..|......|.|:::||:::|..|  |.||
pombe   551 IIIEGAELFNESPSDGIAFLTQHSIIKQSDNPTCIVEFFHSTNRLSKRVLGEFLTKGSN--SHIL 613

  Fly   711 INFVDSFDFTGLRVDQALRLYLETFRLPGEAPLIFLVLEHFSDHWHKQNQDPFANVDAAFRLAYA 775
            ..|:.:|||.|.|:|:||||.|::||||||:.||..|||.||.::...|.|..::.||||.|:|:
pombe   614 NAFISAFDFKGKRIDEALRLLLQSFRLPGESQLIERVLETFSHYYMSANPDSMSSKDAAFVLSYS 678

  Fly   776 IIMLNMDQHNSNAKRLNVPMTLEDFTKNLRGLNGGEDFDQEMLAQVFNAIKNEEIVMPAEQTGLV 840
            |||||.||||.|.|... .|||:||.:|:||:|.|:|||:..|::::.|||..||::..|....:
pombe   679 IIMLNTDQHNPNIKSQR-RMTLDDFCRNVRGVNDGQDFDRNFLSEIYKAIKENEIIVAEEHDTEL 742

  Fly   841 RENYQWKVL---------LRRGDTHDGHFHYVHDASYDVEIFNIVWGASLSALSFMFDKSTE-TG 895
            ...|.|..|         .:|..::      |||..    :|..||.:.::||.::|..:|| |.
pombe   743 SFLYIWSKLQQSVKITEPFKRSSSN------VHDKI----VFLEVWKSIMAALIYVFSTATEDTV 797

  Fly   896 YQRTLAGFSKSAAISAHYNLHSDFDALVLTLCKFTTL-LSSVEQHEPAPANNE-----------T 948
            :.|.:.|..::..::|.|.|:...|..:...|:||.| .|||    |....|.           :
pombe   798 FYRVVNGIQQATEVAAAYELNEPVDYAIERFCQFTALDPSSV----PGTQLNTAIKVEDRIITVS 858

  Fly   949 QQAVNFGLNGKAQAAMRTVFLLVHDYGDCLRESWKHILDLYLQLFRLKLLPKSLI--------EV 1005
            :.:|.||.:.:||.|:..:|.:...:|:.:..||..::.|.:.|.|..|:..|.:        :.
pombe   859 ELSVRFGRDFRAQLALLVLFWISSKFGNIIDASWPLLVQLTICLARNNLIDNSFLPGFKLFGYQW 923

  Fly  1006 EDFCEANGKAMLILEKPREKQESGLFSSLYSFISSEGQRE---PTYEEQDFIKLGRKCIKECQLD 1067
            ..|.|    ..|...||...:|.||.|:|.|::||....|   ||.||.........||...::|
pombe   924 FPFPE----PPLNSGKPALSKEGGLLSALSSYLSSYANDEPPCPTDEEIQHTLCTIDCISSAKID 984

  Fly  1068 QMLQESKFVQLE--SLQELLKCVLALLKAPQGHKSIGLPYAEDQTVFWMEFLVKIVVHNRDRMIP 1130
            ..|  :|.|.|:  .|.:||..:|:|     .:.|..| ..::.||             .|..:.
pombe   985 NFL--TKLVDLKQPGLNKLLDSLLSL-----SNPSTSL-LTDENTV-------------DDNKVS 1028

  Fly  1131 LWPAVRDQMYLLLMGSASCGYDYLLNRCIVAVLKLAIYLMRNEELCPIVLQSLKMLLMLKPALLL 1195
            ...|:.:                 :...|||.|..:::|...|.     |..|:....:...||.
pombe  1029 SVEALSN-----------------IQSAIVADLLTSLFLGTRES-----LNKLERRTQILSYLLF 1071

  Fly  1196 RISK--------QISIGIYEL-----LKTSAQNIHSEQDWQIIFNLLECVGAGAVPPNYDDAQLP 1247
            :|.:        |:|:.|:|:     ||.|    .:.:||.:...|..
pombe  1072 QIEQSGDEKVINQLSLYIFEMFMDDDLKLS----ENSEDWGLFSKLCN----------------- 1115

  Fly  1248 LPPNGSAKSDGAISGEEDATAVPERGYTSDSEITKASAAPAVSSPSAENWILVNNKDSELTTASR 1312
                                                               |:|:|:    ...|
pombe  1116 ---------------------------------------------------LLNDKN----IVVR 1125

  Fly  1313 PQSPPSLSAPPVNTLVYNCQLLDHAPFALFKCWDSLAFIVRSVAHIT-------------PYN-- 1362
            .||           |....||::..|| |.:.|..|..:..:|...|             |.|
pombe  1126 NQS-----------LSLFHQLVNKYPF-LLESWIGLQLVQSAVNTNTADIDDLYRLLSKIPTNLL 1178

  Fly  1363 ----FEACVRCIRIFVEACRDGGIRQRRKLESAAKQKSSKKRSERKPGMASSASSSNLTLLTGDP 1423
                |:..:.|:...::..    ::|..::.|..|:.:||                      |.|
pombe  1179 DLPMFQVYLGCVDTLIQTI----VKQIAQILSKQKKGASK----------------------GLP 1217

  Fly  1424 SDNQI-NGNAAEQEDLAQRYEQLSIQLLDLMYTLYTRTAQIFRWWAEEGCTVPQSAALWSPGWCP 1487
            .|..| :.::||..|               .:.|:.:.|..::..:.|     .|.......|..
pombe  1218 FDKSILDNHSAELND---------------AFNLFLKAAVEYKVDSNE-----SSEHFQDTRWKI 1262

  Fly  1488 LLQGIARLAMDRRREVRTHAISCLQQRALLVHDL-QTLSGTEWCSCFHQVLFPLLNELL------ 1545
            :...:.:|.:.|.|.:|..::||||:  ::|..| |....:...:.||.||.|.:..::
pombe  1263 IYDHVCKLCLSRSRSLRAASLSCLQR--IVVEQLDQPHEVSYTMALFHLVLLPTMENMITVLTEK 1325

  Fly  1546 PESNAAGQLDAALLEESRIRTATIMSKVFLQHLTTLIELGNAFNELWLDILDYIERFMKV-GSDT 1609
            ||....|...|.:.        .|:.|..|..:..|.......:.|||.::|...:...: ||::
pombe  1326 PEHKIFGLAQAQMF--------NIICKTVLIDMNVLSAQKEMLHTLWLKLMDVAIKLSSIHGSES 1382

  Fly  1610 LSEQMQEILKNMLLVMHSVRVFHNQ----DGSLQQAL---WELTWRRIGEFLPNLKEEL-FHDEG 1666
            ::|.|:.| ||:.:::|........    |..:...|   |..||..:..:.|.|..:| .::|.
pombe  1383 MAEVMESI-KNVFMILHGAGALAGPTIEVDPEIPDHLIKTWNTTWNNLFIYYPELSNDLNINNEA 1446

  Fly  1667 K-RAQTLTNPAPQAAV 1681
            : :.:.|.||:....|
pombe  1447 EMKKENLKNPSQTTTV 1462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
garz	NP_610761.2	COG5307	346..>1062	CDD:227623	226/799 (28%)
		Sec7_N	370..512	CDD:289549	49/186 (26%)
		Sec7	643..830	CDD:279680	83/186 (45%)
SPBC211.03c	NP_596613.1	Sec7_N	287..475	CDD:289549	49/187 (26%)
		COG5307	289..1303	CDD:227623	304/1274 (24%)
		Sec7	548..732	CDD:279680	83/186 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	168	1.000	Domainoid score	I922
eggNOG	1	0.900	-	-		E1_COG5307
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	469	1.000	Inparanoid score	I275
OMA	1	1.010	-	-		QHG55524
OrthoFinder	1	1.000	-	-		FOG0003083
OrthoInspector	1	1.000	-	-		oto101635
orthoMCL	1	0.900	-	-		OOG6_102130
Panther	1	1.100	-	-	O	PTHR10663
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2128
SonicParanoid	1	1.000	-	-		X2055
TreeFam	0	0.000	Not matched by this tool.
	11	10.990