Protein Alignment garz and Iqsec2

DIOPT Version :9

• Sequence 1: NP_610761.2
• Gene: garz / 36337
• FlyBaseID: FBgn0264560
• Length: 1983
• Species: Drosophila melanogaster
• Sequence 2: XP_006528905.1
• Gene: Iqsec2 / 245666
• MGIID: 3528396
• Length: 1520
• Species: Mus musculus
• Alignment Length: 614
• Identity: 140/614 - (22%)
• Similarity: 233/614 - (37%)
• Gaps: 206/614 - (33%)

  Fly   557 NCAASKNSSNNRESLPEAAPATG-----GSRHSRHNSGLEGIVIDSGNSVAAEEKVENIASFINA 616
            ||:   :.|::|:||.| .||||     ..|.:||          |.:|.|....|      :..
Mouse   742 NCS---SGSSSRDSLRE-PPATGLCKQTYQRETRH----------SWDSPAFNNDV------VQR 786

  Fly   617 SSHRLRLQSGGEGVGITSEQLAKVKQKKRLLSQGTERFNQRPEKGIQYLQEHGILNAELDPMQVA 681
            ..:|:                            |...||::||||||||.|.|.|:.  .|:.||
Mouse   787 RHYRI----------------------------GLNLFNKKPEKGIQYLIERGFLSD--TPVGVA 821

  Fly   682 LFLRENPGLDKKMIGEYI-SKKKNVDSKILINFVDSFDFTGLRVDQALRLYLETFRLPGEAPLIF 745
            .|:.|..||.::||||:: :::|..:..:|...||..||:.:.:|.|||.:....|:.|||..:.
Mouse   822 HFILERKGLSRQMIGEFLGNRQKQFNRDVLDCVVDEMDFSSMDLDDALRKFQSHIRVQGEAQKVE 886

  Fly   746 LVLEHFSDHWHKQNQ---DPFANVDAAFRLAYAIIMLNMDQHNSNAKRLNVPMTLEDFTKNLRGL 807
            .::|.||..:...|.   ..|.|.|..|.||:|||:||.|.::.:.| ....|.|:||.|||||:
Mouse   887 RLIEAFSQRYCVCNPALVRQFRNPDTIFILAFAIILLNTDMYSPSVK-AERKMKLDDFIKNLRGV 950

  Fly   808 NGGEDFDQEMLAQVFNAIKNEEIVMPAEQTGLVRENYQWKVLLRRGDTHDGHFHYVHDASYDVEI 872
            :.|||..:::|..::..|:..|:                       .|:|.|...|.
Mouse   951 DNGEDIPRDLLVGIYQRIQGREL-----------------------RTNDDHVSQVQ-------- 984

  Fly   873 FNIVWGASLSALSFMFDKSTETGYQRTLAGFSKSAAISAHYNLHSDFDALVLTLCKFTTLLSSVE 937
                                  ..:|.:.|  |...:|..:.                .|:...:
Mouse   985 ----------------------AVERMIVG--KKPVLSLPHR----------------RLVCCCQ 1009

  Fly   938 QHEPAPANNETQQAVNFGLNGKAQAAMRTVFLLVHDYGDCL-----------------RESWKHI 985
            .:| .|..|..|:   .||:      .|.|||    :.|.|                 |:|:. :
Mouse  1010 LYE-VPDPNRPQR---LGLH------QREVFL----FNDLLVVTKIFQKKKILVTYSFRQSFP-L 1059

  Fly   986 LDLYLQLFR-------LKLLP-----------------------------KSLIEVEDFCEANGK 1014
            :::::|||:       :|||.                             :|:.||::..:...:
Mouse  1060 VEMHMQLFQNSYYQFGIKLLSAVPGGERKVLIIFNAPSLQDRLRFTSDLRESIAEVQEMEKYRVE 1124

  Fly  1015 AMLILEK----PREKQESGLFSSLYSFISSEGQREPTYEEQDFIKLGRKCIKECQLDQMLQESKF 1075
            :.|..:|    |...|..|...|:...: :....|.||...|.:|.|........|....:..:.
Mouse  1125 SELEKQKGMMRPNASQPGGAKDSVNGTL-ARSSLEDTYGAGDGLKRGALSSSLRDLSDAGKRGRR 1188

  Fly  1076 VQLESLQELLKCVLALLKAPQGHKSIGLP 1104
            ..:.||...::.  :::.:|:.|:.:..|
Mouse  1189 NSVGSLDSTIEG--SVISSPRPHQRMPPP 1215

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
garz	NP_610761.2	COG5307	346..>1062	CDD:227623	134/570 (24%)
		Sec7_N	370..512	CDD:289549
		Sec7	643..830	CDD:279680	70/190 (37%)
Iqsec2	XP_006528905.1	ATG16	<23..>64	CDD:370001
		Sec7	785..973	CDD:366596	71/218 (33%)
		IQ_SEC7_PH	993..1125	CDD:374551	26/162 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167838949
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5307
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740