Protein Alignment garz and PSD3

DIOPT Version :10

• Sequence 1: NP_610761.2
• Gene: garz / 36337
• FlyBaseID: FBgn0264560
• Length: 1983
• Species: Drosophila melanogaster
• Sequence 2: NP_001399795.1
• Gene: PSD3 / 23362
• HGNCID: 19093
• Length: 1175
• Species: Homo sapiens
• Alignment Length: 1017
• Identity: 200/1017 - (19%)
• Similarity: 342/1017 - (33%)
• Gaps: 284/1017 - (27%)

  Fly   206 SDTMLQKRFTIGDAASGATQEKLKRKTVAQAQTAPRKSSAVEEP--------PQTPQSANLTVPG 262
            |.|:...:....||.|..:.:::::    :..||.||:..|.:.        |:.|.||.:|...
Human   248 SGTLQATKVLDQDAVSSFSVQQVEK----ELDTASRKTQRVNKTLPAGQKNLPEIPLSAEVTTEE 308

  Fly   263 HLKAPILATTPASPAGNILDMQGKITQTPTTTASTGEDETTVPETPVIQVESTESEPLLDGETG- 326
            .....|.....|...|   |.|.:|:|. ......|......|..|:..:.|:.......|..|
Human   309 SFYLSIQKDLTALLTG---DTQAEISQI-MNNGRKGAVCVQEPSCPLASLGSSAVTCHSAGSVGF 369

  Fly   327 ----------------EATSTLAEANSSEYINSVGV---------RFTQQSTDHDVTSLSPYGLP 366
                            :.:|::......:::...||         |.||...|.: |||.....|
Human   370 LKEQRSALGREHPGGCDRSSSMGRPGRVKHVEFQGVEILWTGGDKRETQHPIDFE-TSLQRTASP 433

  Fly   367 FIQE---LFRFLII---LCN---------------PLDKQNSDSMMHTGLSLLTVAFEVAADNIG 410
            ..:|   :.|.||.   |||               |.::..:.|...:.:.|         |..|
Human   434 DSKESSKVPRHLISSAGLCNSSSLTENVWDESWKAPSERPGTSSGTFSPVRL---------DESG 489

  Fly   411 KYEGLLELVKDDLCRNLISLLSSERLSIFAADLQLCFLLFESLRGHLKFQLEAYLRKLSEIIASD 475
            :.|..|:..|..|.:........||:|                      :.|.:::...|.|..
Human   490 EDEVFLQENKQHLEKTPKPERDRERIS----------------------EQEEHVKGEDEDILG- 531

  Fly   476 NPKTPYEMRELALDNLLQLWRIPGFVTELYINYDCDLYCTDMFESLTNLLSKYTLSATNAVYSTH 540
                                  ||:..:     ..|:| :..||::        |..|:..||..
Human   532 ----------------------PGYTED-----STDVY-SSQFETI--------LDNTSLYYSAE 560

  Fly   541 IISMDTLLSVIDSI----------------ERNCAASKNSSNNRESLPEAAPATGGSRHSRHNSG 589
              |::||.|..||.                |......:.|....:.:...: |.||.... ::||
Human   561 --SLETLYSEPDSYFSFEMPLTPMIQQRIKEGGQFLERTSGGGHQDILSVS-ADGGIVMG-YSSG 621

  Fly   590 LEGIVIDSGNSVAAEEKVENIASFINASSHRLRLQSGGEGVGITSEQLAKVKQKKRLLSQGTERF 654
            :...:.|:.:|:..:...|......||.....||::..|   :.|.::.: |:....||.||...
Human   622 VTNGLNDASDSIYTKGTPEIAFWGSNAGVKTTRLEAHSE---MGSTEILE-KETPENLSNGTSSN 682

  Fly   655 NQRPEKGIQYLQEHGILNAELDPMQVALFLRENPGLDKKMIGEYISKKKNVDSKILINFVDSFDF 719
            .:..::..:.|            .|:..|.|.:       :.:::.|.......:...::..|||
Human   683 VEAAKRLAKRL------------YQLDRFKRSD-------VAKHLGKNNEFSKLVAEEYLKFFDF 728

  Fly   720 TGLRVDQALRLYLETFRLPGEAPLIFLVLEHFSDHWHKQNQDPFANVDAAFRLAYAIIMLNMDQH 784
            ||:.:||:||.:.:.|.|.||......||.|||:.:...|.|..|:.|....|..||::||.|.|
Human   729 TGMTLDQSLRYFFKAFSLVGETQERERVLIHFSNRYFYCNPDTIASQDGVHCLTCAIMLLNTDLH 793

  Fly   785 NSNAKRLNVPMTLEDFTKNLRGLNGGEDFDQEM---------------------------LAQVF 822
            ..|   :...||.::|..||:|:|.|.||.:::                           ||.::
Human   794 GHN---IGKKMTCQEFIANLQGVNEGVDFSKDLLKVKLSQFFSSLVFGHHYFRISTCSSALAALY 855

  Fly   823 NAIKNEEI----------VMPAEQTGLVRENYQWKVLLRRGDTHDGHFHYVHDASYDVEIFNIVW 877
            |:||||::          ..|:|.|.........|.:.|.|.|.:......||.:
Human   856 NSIKNEKLEWAVDDEEKKKSPSESTEEKANGTHPKTISRIGSTTNPFLDIPHDPN---------- 910

  Fly   878 GASLSALSFMFDKSTETGYQRTLAGFSKSAAISAHYNLHSDFDA-----------LVLTLCKFTT 931
                                   |...||..::.  .:|:|.|.           ....:.|.|.
Human   911 -----------------------AAVYKSGFLAR--KIHADMDGKKTPRGKRGWKTFYAVLKGTV 950

  Fly   932 LLSSVEQHEPAPANNE----TQQAVNFGLNGKAQAAMR--TVF---------LLVHDYGDCLRES 981
            |....::::|..|.:|    ...:|:..|..||....:  .||         ||.........:.
Human   951 LYLQKDEYKPEKALSEEDLKNAVSVHHALASKATDYEKKPNVFKLKTADWRVLLFQTQSPEEMQG 1015

  Fly   982 WKHILDLYLQLFRLKLLPKSLIEVEDFCEANGKAMLILEKPREKQESGLFS--SLYSFISSEGQR 1044
            |.:.::....:|.....|.::...:.|    .:.:|.....:..||..|.|  |....|::|...
Human  1016 WINKINCVAAVFSAPPFPAAIGSQKKF----SRPLLPATTTKLSQEEQLKSHESKLKQITTELAE 1076

  Fly  1045 EPTYEEQDFIKLGRKCIKECQLDQMLQESKFVQLESLQELLK 1086
            ..:|.....:|  .|.:.|.:|.....|.:..:.|....:||
Human  1077 HRSYPPDKKVK--AKDVDEYKLKDHYLEFEKTRYEMYVSILK 1116

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
garz	NP_610761.2	PLN03076	<395..>986	CDD:215560	132/669 (20%)
		Sec7	643..830	CDD:460178	56/213 (26%)
PSD3	NP_001399795.1	Sec7	682..863	CDD:238100	52/202 (26%)
		PH_EFA6	908..1033	CDD:270107	23/159 (14%)