Protein Alignment garz and iqsec1a

DIOPT Version :9

• Sequence 1: NP_610761.2
• Gene: garz / 36337
• FlyBaseID: FBgn0264560
• Length: 1983
• Species: Drosophila melanogaster
• Sequence 2: NP_001373523.1
• Gene: iqsec1a / 100334106
• ZFINID: ZDB-GENE-120813-2
• Length: 1000
• Species: Danio rerio
• Alignment Length: 1209
• Identity: 246/1209 - (20%)
• Similarity: 405/1209 - (33%)
• Gaps: 414/1209 - (34%)

  Fly    18 LMTAMRRGTRWNATAYVDDENDSLL-----KLFIDLKHELNRIEDL---RQIEPQVFLAPFLEVI 74
            |:|...|..|.|:.....:...|.:     .|.:::....|.:...   |.:..:.:.:..|.|.
Zfish    61 LLTCRLRSIRENSPEQQSEYGGSRIVRRHASLPVEMTDSPNSLRSAVCRRTVPCRQWKSASLGVE 125

  Fly    75 RTADAT--GPLTSLALASVNKLLSYGLIDPTSPNLADIVERIADAVTHARFMGTDQSSDGVTFMR 137
            .|.:::  ||       ||:..:.||                ...|||:..:..|| |:|..:.
Zfish   126 GTVESSEPGP-------SVDTSIGYG----------------RGPVTHSSSLSPDQ-SEGSLYS- 165

  Fly   138 VIEVLHTLIRSPEGAAVSNVSMCEVMLSCFKISFEPRL---SELLRRSAE-------KSLKDMVL 192
                 |::...|:...                  .|:|   ..:||:.||       :||.:.
Zfish   166 -----HSIQSGPQRPQ------------------RPKLQHSQSILRKQAEEEAIKRSRSLSES-- 205

  Fly   193 LFFMRLPQFAEERSDTMLQKRF-----------TIGDA-------------ASGATQEKLKRKTV 233
               ..|....:::...||::::           ||..|             .|..::.::.|:.:
Zfish   206 ---YELSTDLQDKKVEMLERKYGGRFITRHAARTIQTAFRHYQMNKNFERLRSSMSENRMSRRIL 267

  Fly   234 AQ------AQTAP----------RKSSAVEEPPQTPQSANLTVPGHLKAPILATTPASPAGNILD 282
            ..      :..||          |:.|.:||   :.....:..||. |.|::...|        :
Zfish   268 LSNMRMQFSFEAPEKVHSSFFEGRQMSLMEE---SSHIGAMVQPGE-KVPVILEAP--------E 320

  Fly   283 MQGKITQTPTTTASTGEDETTVPETPVIQVESTESEPLLDG--------ETGEATSTLAEANSSE 339
            .|..:|.|.|      |.|.|..:    ||:|. :|.:.|.        |..:...|:.|....
Zfish   321 TQNDLTDTIT------ELEDTFSK----QVKSL-AESIDDALNCRSLHKEEIQPEQTVCELQQK- 373

  Fly   340 YINSVGVRFTQQSTDH-------DVTSLSPYGLPFIQELFRFLIILCNPLDKQNSDSMMHTGLSL 397
                   |...|..:|       |||.       ||.|  ..|..|..|...::.........|.
Zfish   374 -------RELPQPDEHHRLDEICDVTL-------FIDE--EELSPLVQPSSAESDQHTQSVSASQ 422

  Fly   398 LTVAFEVAADNIGKYEGLLELVKDDLCRNLISLLSSERLSIFAADLQLCFLLFESLRGHLKFQLE 462
            ...:.:...|...:....|:.....||.:| .:|:.|..|..:||
Zfish   423 EYWSMDANMDTSARSTPSLDYQSPKLCVDL-PVLTIEPPSDSSAD-------------------- 466

  Fly   463 AYLRKLSEIIASDNPKTPYEMRELALDNLLQLWRIPGFVTELYINYDCDLYCTDMFESLTNLLSK 527
                      |||..:          ..|:|...:|                            |
Zfish   467 ----------ASDRSE----------QGLVQTQNVP----------------------------K 483

  Fly   528 YTLSATNAVYSTHIISMDTLLSVIDSIERNCAASKNSSNNRESLPEAAP---------------- 576
            .|.:|..|                              |.:..||...|
Zfish   484 QTTAAPRA------------------------------NPKHGLPARVPSLSGEEEPLRHRQVVS 518

  Fly   577 --ATGGSRHSRHNSGLEGIVIDSGNSVAAEEKVENIASFINASSHRLRLQSGGEGVGITSEQLAK 639
              ||.|||.|:..|.......||.||  ....::.|.|..::|...|..|:..:....:.:..|.
Zfish   519 HLATNGSRQSKSESDFSDGDNDSINS--NSNSIDTINSESSSSQQNLSKQTYHKDTRNSWDSPAS 581

  Fly   640 VK--QKKRLLSQGTERFNQRPEKGIQYLQEHGILNAELDPMQVALFLRENPGLDKKMIGEYI-SK 701
            ..  .:||....|...||::||||||||.|.|.:..  .|:.||.||.:..||.::||||:: ::
Zfish   582 SSDIMRKRQYRIGLNLFNKKPEKGIQYLTERGFIPD--TPVGVAHFLLQRKGLSRQMIGEFLGNR 644

  Fly   702 KKNVDSKILINFVDSFDFTGLRVDQALRLYLETFRLPGEAPLIFLVLEHFSDHWHKQNQD---PF 763
            :|..:..:|...||..||:|:.:|:|||.:....|:.|||..:..::|.||..:...|.|   .|
Zfish   645 QKQFNRDVLDCVVDELDFSGMELDEALRKFQAQIRVQGEAQKVERLIEAFSQRYCICNHDVVRQF 709

  Fly   764 ANVDAAFRLAYAIIMLNMDQHNSNAKRLNVPMTLEDFTKNLRGLNGGEDFDQEMLAQVFNAIKNE 828
            .|.|..|.||:|||:||.|.::.|.| :...|.||||.|||||::.|||..:|||..::..|:.:
Zfish   710 RNPDTIFILAFAIILLNTDMYSPNVK-IERKMKLEDFVKNLRGVDDGEDIPREMLVGIYERIQKK 773

  Fly   829 EIVMPAEQTGLVRENYQWKVLLRRGDTHDGHFHYVHDASYDVEIFNIVWGASLSALSFMFDKSTE 893
            |:                       .|::.|...|...
Zfish   774 EL-----------------------KTNEDHVSQVQKV--------------------------- 788

  Fly   894 TGYQRTLAGFSKSAAISAHYNLH---SDFDALVLTLCKFTTLLSSVEQHEPAPANNETQQAVNFG 955
               ::.:.|  |....|.|:.|.   |.....::..|:...:          |..|..|:.
Zfish   789 ---EKLIVG--KKQMGSLHHGLGCVLSQAHRRLVCYCRLFEV----------PDPNRLQKL---- 834

  Fly   956 LNGKAQAAMRTVFLLVHDYGDCL-------------RESWKHILDLY---LQLFRLKLLPKSLIE 1004
              |:.|   |.:||    :.|.|             ..|::....||   :.||..:..|..:..
Zfish   835 --GQHQ---REIFL----FNDLLVVTKIFQKKKNSVTYSFRQSFSLYGMQVMLFENQFYPNGIRL 890

  Fly  1005 VEDFCEANGKAMLILEKPREKQESGLFSSLYSFISSEGQREPTYEEQDFIKLGRKCIKECQLDQM 1069
            ......|:.|.::....|..:......|.|         ||...|.|:        :::.:::..
Zfish   891 TSAIPGADFKVLINFNAPNIQDRKRFISDL---------RESIAEVQE--------MEKYRIESE 938

  Fly  1070 LQESKFVQLESLQELLKCVLALLKAPQGHKSIGLPYAED 1108
            |::.|.|...|:.:    .::.||...|:.|:|....:|
Zfish   939 LEKQKGVVRPSMSQ----SMSGLKKETGNGSMGRTSLDD 973

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
garz	NP_610761.2	COG5307	346..>1062	CDD:227623	167/765 (22%)
		Sec7_N	370..512	CDD:289549	21/141 (15%)
		Sec7	643..830	CDD:279680	77/190 (41%)
iqsec1a	NP_001373523.1	Sec7	587..775	CDD:396096	77/190 (41%)
		IQ_SEC7_PH	807..942	CDD:406773	28/174 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582819
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5307
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740