DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30046 and spon2b

DIOPT Version :9

Sequence 1:	NP_001286341.1	Gene:	CG30046 / 36334	FlyBaseID:	FBgn0050046	Length:	839	Species:	Drosophila melanogaster
Sequence 2:	NP_571083.4	Gene:	spon2b / 30202	ZFINID:	ZDB-GENE-990415-161	Length:	331	Species:	Danio rerio

Alignment Length:	311	Identity:	93/311 - (29%)
Similarity:	142/311 - (45%)	Gaps:	19/311 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   178 PTAPAAVDVPCCACDEARYELIFEGVWSRNLHPKDFPTRGWETRFCELLGAAHSSDYRFWESGEL 242
            |..|..||..|.|...|:|.|.|.|.|::...||.:|......::..|:|..|||||..|:..|.
Zfish    24 PAMPVDVDRMCTAPSTAKYRLTFTGQWTQTAFPKHYPLYRPPAQWSPLIGVTHSSDYHLWQRNEY 88

  Fly   243 ASVAMKEYAEHCSSRLLEREF-SINFRDQKIRTIIKARGPSYPNISSKTMASVRVDPIHHMVSFA 306
            ||..::|::|...:..|.:|. :...|.|.:..:..|  |:....:........|...|.::||.
Zfish    89 ASNGVREFSERAEAWTLIKEVEAAGERIQSVYGLFSA--PAVVAGTGHATTEFEVFARHSLLSFI 151

  Fly   307 SKIEPSPDWIVGVTGLELCLRNCTWMEEKVINLYPWDVGTDSGPTYTSSDQPQVPPDVIRRMRSD 371
            .:|.|||||.:||..|.|| ....|.|...:.|||:|.|||||.|::|.:...:|.|.:.::.|.
Zfish   152 VRIVPSPDWFIGVDSLNLC-EGDHWKENISLELYPYDAGTDSGFTFSSPNFETIPQDKVTQITSS 215

  Fly   372 FPNDPRSPFYDISGTPMKPMA---ILTVKRQRIYERRCADEDSNNDP----------DVPRECFT 423
            ||:.|.:.||......:.|:|   :..:|..:|:........||..|          :.|.:|..
Zfish   216 FPSHPANSFYYPRLKHLPPIAKVSLTKIKNNQIFSLPIQPTQSNQIPSGNEIDGPLINTPLDCEV 280

  Fly   424 HPWSSWSDCSSKCG-VGMQYRRRVYKQPELARVYNCNEAQYEERECQGEMC 473
            ..||.|..|..:|| .|:::|.|............|...: |:|.|..:.|
Zfish   281 SVWSPWGLCKGQCGEKGVKHRTRYIHTHPANNGAPCPSLE-EKRLCIPDNC 330

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30046	NP_001286341.1	Reeler	28..167	CDD:260081
		Spond_N	194..382	CDD:283999	63/188 (34%)
		TSP1	425..473	CDD:214559	13/48 (27%)
		TSP1	510..561	CDD:214559
spon2b	NP_571083.4	Spond_N	40..227	CDD:283999	64/189 (34%)
spon2b	NP_571083.4	TSP1	280..330	CDD:214559	13/50 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D240419at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010