DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30046 and spon2a

DIOPT Version :9

Sequence 1:	NP_001286341.1	Gene:	CG30046 / 36334	FlyBaseID:	FBgn0050046	Length:	839	Species:	Drosophila melanogaster
Sequence 2:	NP_571082.1	Gene:	spon2a / 30201	ZFINID:	ZDB-GENE-990415-160	Length:	334	Species:	Danio rerio

Alignment Length:	301	Identity:	95/301 - (31%)
Similarity:	141/301 - (46%)	Gaps:	23/301 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   188 CCACDEARYELIFEGVWSRNLHPKDFPTRGWETRFCELLGAAHSSDYRFWESGELASVAMKEYAE 252
            |.|...|.|.::|.|.||....||.:|......::.:|:...|:..||.|:.|..||..||.:||
Zfish    38 CSARGPASYIVVFTGHWSPQTFPKQYPLFRPPAQWSKLMVVTHNEQYRLWQEGAPASDGMKSFAE 102

  Fly   253 HCSSRLLEREFSINFRDQKIRTIIKARGPSYPNISSKTMASVRVDPIHHMVSFASKIEPSPDWIV 317
            ...:..|.::.....:.:.:.::.:..|  .|:....:...|.:.|...:||...|:.|||||.|
Zfish   103 QGLTVDLVKDAKEARKRRSVGSMYRTAG--IPSGIGHSSTEVLLTPRSPLVSLIVKLIPSPDWFV 165

  Fly   318 GVTGLELCLRNCTWMEEKVINLYPWDVGTDSGPTYTSSDQPQVPPDVIRRMRSDFPNDPRSPFYD 382
            ||.||.|| ....|.:|...:|:|:|.|||||.|::|.:.|..||:.|..:.|..||.|.:.||.
Zfish   166 GVDGLNLC-EGGKWKQEVTFDLHPFDAGTDSGFTFSSPNFPTTPPENITMITSQKPNHPANSFYY 229

  Fly   383 ISGTPMKPMAILTVKRQRIYERRCADEDSNND-PD---------VPRECFTHPWSSWSDCSSKCG 437
            .....:.|:|.:.||||.....|..:..||:. ||         .|.:|....||||..|...|.
Zfish   230 PRLNELPPLATIWVKRQSRLPVRQQNRLSNHILPDASKPHRFSETPLDCEVSMWSSWGLCFGPCA 294

  Fly   438 -VGMQYRRRVYKQPELARVYN----CNEAQYEERECQGEMC 473
             .|:::|.|..    |.:..|    |.|.: |:.||....|
Zfish   295 RGGLRHRTRYI----LLKPANSGSPCPELE-EQEECTPHNC 330

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30046	NP_001286341.1	Reeler	28..167	CDD:260081
		Spond_N	194..382	CDD:283999	62/187 (33%)
		TSP1	425..473	CDD:214559	16/52 (31%)
		TSP1	510..561	CDD:214559
spon2a	NP_571082.1	Spond_N	44..230	CDD:283999	63/188 (34%)
spon2a	NP_571082.1	TSP1	283..330	CDD:214559	16/51 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3539
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D240419at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910