Protein Alignment CG30046 and fat-spondin

DIOPT Version :10

• Sequence 1: NP_725129.1
• Gene: CG30046 / 36334
• FlyBaseID: FBgn0050046
• Length: 839
• Species: Drosophila melanogaster
• Sequence 2: XP_320745.5
• Gene: fat-spondin / 1280875
• VectorBaseID: AGAMI1_008567
• Length: 781
• Species: Anopheles gambiae
• Alignment Length: 819
• Identity: 243/819 - (29%)
• Similarity: 361/819 - (44%)
• Gaps: 173/819 - (21%)

  Fly     2 WWSSGAPLVELLLLGSLVIGRVSSLICTRRPANTG----SPKSPVDENFMISVSGNPETYILGQE 62
            |.|...|.: |.:|.:||....|   |::.|...|    ..|.|.|..:.:::...|..|..|:.
Mosquito    13 WRSIVLPAL-LFVLPALVENGES---CSKTPIVDGRTVSGVKQPGDNGYRLAIRDEPTGYEPGKI 73

  Fly    63 YNVSLNAFNGH----RYISFIMALENENGDFSY---NDDLGRFEL-SDLIETRFSPNCINMVENT 119
            ||:.:.....|    ::..|.:.....||...|   ...:|||:| ||.: |:|...|:|.|...
Mosquito    74 YNLFIVGSRTHAKLQQFTHFTLVAHARNGAKQYLAGPRRVGRFQLFSDAL-TKFHDQCVNTVTQA 137

  Fly   120 NTNSKTHMHLTWVAPSEPGSGCVLIRATVQQHREVWHMDDGGLTKRICEEVTDDVESQPTAPAAV 184
            :...||.:.:.||||: .|||||.|.|.|.:..:.|..|||.|||.:||.       || .|...
Mosquito   138 DDFPKTEVQVMWVAPA-AGSGCVSISAMVYESEQQWFADDGALTKVLCEH-------QP-VPRLQ 193

  Fly   185 DVPCCACDEARYELIFEGVWSRNLHPKDFPTRGWETRFCELLGAAHSSDYRFWESGELASVAMKE 249
            ...|||||||:|.|.|||:||...||||:|...|.|.|.:::||:|.:::.||....:|:...:.
Mosquito   194 KGECCACDEAKYSLTFEGIWSNETHPKDYPFAIWLTHFSDVIGASHDTNFSFWGENHIATDGFRM 258

  Fly   250 YAEHCSSRLLEREFSINFRDQKIRTIIKARGPSYPNISSKTMASVRVDPIHHMVSFASKIEPSPD 314
            .||..|.||||.|  :..:..::||:|||.|..||.:::.|.::.|||..||.:|.||...||||
Mosquito   259 LAEWGSVRLLETE--LRAKGARLRTLIKAAGLWYPRVNANTTSNFRVDRKHHKISLASMFGPSPD 321

  Fly   315 WIVGVTGLELCLRNCTWMEEKVINLYPWDVGTDSGPTYTSSDQPQVPPDVIRRMRSDFPNDPRSP 379
            |:|||:||:||..:|||.|...::|||||.|||||.:|.|::....|.:.:.|:.:.:|.|||:|
Mosquito   322 WVVGVSGLDLCRPDCTWTESLDVDLYPWDAGTDSGISYMSANAETQPRERMHRITTLYPEDPRAP 386

  Fly   380 FYDISGTPMKPMAILTVKRQRIYERRCADED----------SNNDPDVPRECFTHPWSSWSDCSS 434
            ||:.....|.|:|.|.::|:|:..|.| ||.          .|.:.:...||.|..::.|:.||.
Mosquito   387 FYNPRSAEMTPLARLYLRRERVMARSC-DEQFLQAQVLELAENTEEETRPECATTEYTDWTPCSV 450

  Fly   435 KCGVGMQYRRRVYKQPELARVYNCNEAQYEERECQGEM--------------------------- 472
            .||.|::.|.|.|.:|::|....||.....:..|..|:
Mosquito   451 TCGKGIRMRTREYLRPDVAAGARCNRQLIGKEMCVAEVPECEEGVAGEDASGEDMGQSAATVDEA 515

  Fly   473 ---------------------CGQNNLMR-------------------------EPE-EFEDLE- 489
                                 ||....||                         :|: ...|:|
Mosquito   516 GEGVGVCRTTRWSEWSECSVSCGIGVTMRTRTFLENMGRKKCPHISVVEKQKCMQPDCSITDMEA 580

  Fly   490 PDPRRIGYQPSQQRRAECELSSWGSWSPCSVTCGDGYEMRQR-QYLNPQAEFDCQGVHRMELQET 553
            |||.             |.:::|..|||||.|||.|.::|.| ..|.|:.:..||  :|:||.:.
Mosquito   581 PDPL-------------CPVTAWSDWSPCSATCGKGVQIRTRLLLLAPEEQDRCQ--NRIELNQQ 630

  Fly   554 RKCSGR-DCLGSLPGSYSTDMDSPYGGASPGRIGGNMYGPQLEPEAENFGDYDDSRNGAVGGFEV 617
            |.|:.: |||.....:......||..|...||.....|               ||..|....|..
Mosquito   631 RPCTDKADCLYDTFTAQEICSQSPEAGPCRGRYQRYAY---------------DSTKGTCVPFYY 680

  Fly   618 GNLKGNIGNW-----ALNR------QTNLGRDVPSLRPTNYDRARQQAEKSERTTWS------GQ 665
            |..:||..|:     .:|.      :|:.|....:..|..::........|:.:.|:      |.
Mosquito   681 GGCRGNRNNFLTADDCMNTCTRSRLETSTGLPPAAATPDPFEALPVDCVLSDWSEWTPCSVTCGT 745

  Fly   666 SRPDDPRLEDVERAPWHRQRPSNKYGSIVEAPEMVSPRE 704
            .|.:  |:..:...|.:..:|.        .|.:|..|:
Mosquito   746 GRSE--RVRSIVTHPRNGGQPC--------PPRIVKRRK 774

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30046	NP_725129.1	Reeler	28..167	CDD:260081	48/150 (32%)
		Spond_N	194..390	CDD:461924	85/195 (44%)
		TSP1	425..473	CDD:214559	15/95 (16%)
		TSP1_spondin	507..561	CDD:465948	22/55 (40%)
fat-spondin	XP_320745.5	None