Protein Alignment CG17739 and spon1b

DIOPT Version :10

• Sequence 1: NP_610757.1
• Gene: CG17739 / 36333
• FlyBaseID: FBgn0033710
• Length: 873
• Species: Drosophila melanogaster
• Sequence 2: XP_005174403.1
• Gene: spon1b / 58029
• ZFINID: ZDB-GENE-000427-10
• Length: 804
• Species: Danio rerio
• Alignment Length: 931
• Identity: 282/931 - (30%)
• Similarity: 424/931 - (45%)
• Gaps: 204/931 - (21%)

  Fly     5 EGFTILLALVGVI---------------PRIEG--CIRVPPGVTAAKSPVDDNYVLSVNGNTQSY 52
            :|..:||..:.|.               .|.||  |..:.....:|:....:.:.|.|.|..::|
Zfish     5 DGLVVLLVFLNVFLIHSDAFKRDTAERHSRSEGGFCRILRTQARSARRDGQNEFRLKVEGEPETY 69

  Fly    53 VPGQRYNVSLSAFSGLSFISFMLALDLESGDGDGDANALGTWEIADLAETRFSPRCPNLVENTNT 117
            .||..|.|||.|.|...|..|.|....|..:|....:..||:::.|.::|:|...||..|..:..
Zfish    70 QPGSTYRVSLYASSPSYFRGFTLIALKEGREGVSPDDYAGTFKLIDESDTQFMTNCPPAVTESIP 134

  Fly   118 NVKTRVDVFWVAPSSPGQGCILLRATVMQHRDVWFMDDGFLTKRMCEEEVDDIDTQPSIVDPCCA 182
            ..:||:.|||.||.| |.||:.|:|:|:|.|.::|.|:|.||||:||::...|..:|:  ..|||
Zfish   135 RRRTRIQVFWTAPPS-GSGCVTLKASVVQRRIIFFQDEGSLTKRLCEKDPVAITEKPA--QECCA 196

  Fly   183 CDEAKYELTFEGKWSRHTHPKDFP--ANSWRTRFSDIIGASHTLDYRFWQYGELASEGLREVAEH 245
            |..|||.:||.|.||...||||:|  ||.|    |.:||||||..|..|:||..||||:::|:|:
Zfish   197 CGTAKYRVTFYGNWSEKLHPKDYPRRANHW----SALIGASHTRSYVLWEYGGFASEGVKQVSEY 257

  Fly   246 GSTRTLESELKDQSEHIRTIIKARGIAYP-----NVTGKTFAVFRVDSNHHLISLVSMVDPSPDW 305
            ||...:|.|::.:.:.:.|:||.:. .:|     |:.....|.|.||...||:|.::|:.|||||
Zfish   258 GSPVKMEEEIRQKGDDVMTVIKTKA-QWPAWQPLNIRAAPSAEFSVDRVRHLMSFLTMLGPSPDW 321

  Fly   306 IVGVSGLELCLPNCSWVENKVHNLYPWDAGTDSGPSYMSADQPQVPPDVVRRIKSNFPNDPRSPF 370
            .||:||.:||..:|.||:..|.:|.|||||||||.||.|.::|.:|.:.:|.:.|  .:.|:|||
Zfish   322 NVGLSGEDLCTRDCGWVQKLVKDLVPWDAGTDSGVSYESPNKPSIPQERIRPLTS--LDHPQSPF 384

  Fly   371 YDPTGAQMKPLATLHINRRRLYEKNC-----------------ESSDSEQVPPECATNSWSRWDE 418
            |||:|..|.||..:.:.|.....:.|                 |..:.:..|..|..::||.|..
Zfish   385 YDPSGGPMTPLGRVVVERIARKGEQCNTVPDTIDDIVADIAQEEKEEGDNTPETCIYSNWSPWSA 449

  Fly   419 CTTK-CGPGKQYRIREFK---NPALASRHRCNNALREEKNCVGHKCAGFNEETAEGGEPEVAPSP 479
            |::. |..|::.|.|..|   :|.|...|     .::.:.|:|..|   :||.|.
Zfish   450 CSSSTCDKGRRMRQRMLKAQLDPNLPCLH-----TQDFEPCMGPGC---SEEEAS---------- 496

  Fly   480 GSSDDPQCGLSDWSEWSSCTVTCGTGEMTRSRHYLNKKAKKKCQKASRARLHETKICEAMECGGD 544
                  .|.:|:|..||.|:.:||.|..:|.|:     .|:..:..|...|
Zfish   497 ------TCMMSEWISWSPCSASCGMGMRSRERY-----VKQFPEDGSSCTL-------------- 536

  Fly   545 IENEGGAGEPEEEQAGGDGGGSAEKRSIFRNFESYSQHREDYIPPVCGVTPWSDFSPCMGPCG-G 608
                     |.||         .||..:          .:|..|..|.||.|.::.||...|| |
Zfish   537 ---------PTEE---------TEKCVV----------NDDCSPSSCVVTEWGEWEPCSVSCGLG 573

  Fly   609 HGKRQRIRKVWNNNQVYGVTDPNDDGQDPCRHIKLHEEVNCTNPSCDTIVPGFCYDELTDSPCRD 673
            ..:|:|:.|:          |.:|.  .||| :::.|...|..|.|:.:|   |    ..||..|
Zfish   574 MRRRERMMKM----------DASDG--SPCR-VQMAEAEKCMMPECNAVV---C----MLSPWSD 618

  Fly   674 NDVANFWYYDHVSDQCAIYWSDRCDTNRNKFKS-------KEECE--ETCRLPRHKQELQHDGIP 729
                  |      .:|::.......|.:...|:       .:|.|  |.|.||.         .|
Zfish   619 ------W------GECSVSCGVGMRTRQRMLKTPVKPGQCPDELEQVEKCMLPE---------CP 662

  Fly   730 AIDCLVSDWVSHS-CNASCGDGFQLRTRRVLRTPKYGGKPCPKHLVRLDRCYQRCDDMYSISGRG 793
            . ||::|:|.:.| ||.|||.|..:|:|.|...|::||.|||:.:.|.....::|       .||
Zfish   663 T-DCMLSEWSAWSECNKSCGKGHMIRSRMVKLEPQFGGLPCPETVQRKKCKIRKC-------SRG 719

  Fly   794 -----------FGERRHVVRAPQPEPQDE---CRYSEWSAWTPCTATCGDNAVRQRTRTLMNTDL 844
                       ..:||...::.:...::.   |....||:||.||..| |...::|..|:.....
Zfish   720 SRASEKRKRQEVSDRRRAKQSRESVAEESTVVCPIRPWSSWTECTKPC-DGGTQERVMTIKKKGK 783

  Fly   845 SYK---CKDRVRMEKCVMMPC 862
            |.:   ||::..:..|.:.||
Zfish   784 SSQHNHCKNKKEIRACNVHPC 804

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17739	NP_610757.1	Reeler	23..163	CDD:260081	50/139 (36%)
		Spond_N	186..380	CDD:461924	91/200 (46%)
		TSP1_spondin	487..>512	CDD:480609	10/24 (42%)
		TSP1	490..541	CDD:214559	13/50 (26%)
		TSP1_spondin	591..654	CDD:480609	20/63 (32%)
		Kunitz-type	662..714	CDD:444694	11/60 (18%)
		TSP1_spondin	733..>773	CDD:465948	19/40 (48%)
		TSP1_spondin	812..862	CDD:480609	15/52 (29%)
spon1b	XP_005174403.1	Reeler	50..179	CDD:260081	49/129 (38%)
		Spond_N	200..394	CDD:461924	91/200 (46%)
		TSP1_spondin	439..490	CDD:465948	15/55 (27%)
		TSP_1	501..546	CDD:459668	18/81 (22%)
		TSP_1	558..606	CDD:459668	18/60 (30%)
		TSP1_spondin	611..661	CDD:465948	14/74 (19%)
		TSP1_spondin	665..716	CDD:465948	20/50 (40%)
		TSP1_spondin	752..804	CDD:465948	15/52 (29%)