DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17739 and spon2a

DIOPT Version :9

Sequence 1:	NP_610757.1	Gene:	CG17739 / 36333	FlyBaseID:	FBgn0033710	Length:	873	Species:	Drosophila melanogaster
Sequence 2:	NP_571082.1	Gene:	spon2a / 30201	ZFINID:	ZDB-GENE-990415-160	Length:	334	Species:	Danio rerio

Alignment Length:	297	Identity:	94/297 - (31%)
Similarity:	144/297 - (48%)	Gaps:	20/297 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   180 CCACDEAKYELTFEGKWSRHTHPKDFPANSWRTRFSDIIGASHTLDYRFWQYGELASEGLREVAE 244
            |.|...|.|.:.|.|.||..|.||.:|......::|.::..:|...||.||.|..||:|::..||
Zfish    38 CSARGPASYIVVFTGHWSPQTFPKQYPLFRPPAQWSKLMVVTHNEQYRLWQEGAPASDGMKSFAE 102

  Fly   245 HGSTRTLESELKD--QSEHIRTIIKARGIAYPNVTGKTFAVFRVDSNHHLISLVSMVDPSPDWIV 307
            .|.|..|..:.|:  :...:.::.:..||  |:..|.:.....:.....|:||:..:.|||||.|
Zfish   103 QGLTVDLVKDAKEARKRRSVGSMYRTAGI--PSGIGHSSTEVLLTPRSPLVSLIVKLIPSPDWFV 165

  Fly   308 GVSGLELCLPNCSWVENKVHNLYPWDAGTDSGPSYMSADQPQVPPDVVRRIKSNFPNDPRSPFYD 372
            ||.||.|| ....|.:....:|:|:|||||||.::.|.:.|..||:.:..|.|..||.|.:.||.
Zfish   166 GVDGLNLC-EGGKWKQEVTFDLHPFDAGTDSGFTFSSPNFPTTPPENITMITSQKPNHPANSFYY 229

  Fly   373 PTGAQMKPLATLHINRRR---LYEKNCESS----DS------EQVPPECATNSWSRWDECTTKCG 424
            |...::.||||:.:.|:.   :.::|..|:    |:      .:.|.:|..:.||.|..|...|.
Zfish   230 PRLNELPPLATIWVKRQSRLPVRQQNRLSNHILPDASKPHRFSETPLDCEVSMWSSWGLCFGPCA 294

  Fly   425 -PGKQYRIREFKNPALASRHRCNNALREEKNCVGHKC 460
             .|.::|.|........|...|.. |.|::.|..|.|
Zfish   295 RGGLRHRTRYILLKPANSGSPCPE-LEEQEECTPHNC 330

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17739	NP_610757.1	Reeler	23..163	CDD:260081
		Spond_N	186..373	CDD:283999	66/188 (35%)
		TSP1	412..460	CDD:214559	14/48 (29%)
		TSP1	490..541	CDD:214559
		KU	661..715	CDD:294074
		TSP_1	815..862	CDD:278517
spon2a	NP_571082.1	Spond_N	44..230	CDD:283999	66/188 (35%)
spon2a	NP_571082.1	TSP1	283..330	CDD:214559	14/47 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3539
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D240419at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820