DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment salto and FDM4

DIOPT Version :9

Sequence 1:	NP_610756.2	Gene:	salto / 36332	FlyBaseID:	FBgn0061197	Length:	832	Species:	Drosophila melanogaster
Sequence 2:	NP_001318996.1	Gene:	FDM4 / 837939	AraportID:	AT1G13790	Length:	736	Species:	Arabidopsis thaliana

Alignment Length:	780	Identity:	149/780 - (19%)
Similarity:	254/780 - (32%)	Gaps:	289/780 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 KAEKQASDKATWSRTSSCGGVFSTPPTQNGDGSPNKGRLSHIPNRRGASRSSIHSRKTSLERVTS 88
            |.|.....|:|.|.|..  |.|.|  |:| ..||      ||........|...|.::..||:..
plant   102 KEEFTGKWKSTLSTTEE--GEFIT--TEN-SSSP------HIVKAEPKFVSGDDSGRSGEERLKF 155

  Fly    89 STKARPCVSTYSLPNRRVEPEHKVVEPDRKTDIDELNPPKRNVVPIKTHAQSAQLVKSTTCEPYQ 153
            |.|..|..|                      :.|:..|.||..  :.:.|:...       ||.|
plant   156 SDKPDPFFS----------------------NEDKSYPAKRPC--LVSGAKEGD-------EPVQ 189

  Fly   154 NV----------KKPEKMSHRRVLEMNRMRVFDTQKKKLENLQSEFMHKIRL----MGSELRN-- 202
            .:          ..|:|:........::|.| ...|..|.|::..|..|.|.    .||::|.
plant   190 RIGLSHGASFAPTYPQKLVSLGAGNGDQMYV-HPWKGILANMKRTFNEKTRKYAGESGSKIREDL 253

  Fly   203 --------------QGVFKFVGLTVND---------------------ECKLVVHHDDLLRLPKS 232
                          .|...|.|..:.|                     :|....|  ||.|
plant   254 IKKGFNPHKVTPLWNGRLGFTGFAIVDFGKEWEGFRNATMFDKHFEVSQCGKRDH--DLTR---- 312

  Fly   233 IPAESM-------NDLKTRCRAIVDQGVLLIYDHIPRIQRAKNDLEA-SEKREETQKKLSNLVEE 289
            .|.:.:       :|..:|         ..|.||:    |.:.||:: |.|..|.|:|...||..
plant   313 DPGDKLYGWVAKQDDYYSR---------TAIGDHL----RKQGDLKSVSGKEAEDQRKTFTLVSN 364

  Fly   290 KMNLIVEEIEQLCGACSKQESPNKSLYREMSELRSQKQAMEVRYFDAQKEHTEQMNQLRIELDAK 354
            ..|.:|.:.:.|        ...:|:|::.|.:
plant   365 LENTLVTKSDNL--------QQMESIYKQTSSV-------------------------------- 389

  Fly   355 LKQELASRDQIIVELRKSLRRSEDMLSEQSIRLAENNSKLLTEDSTIEVLRSEVAKLKTVKEQMV 419
                          |.|.::..::|::              |.:..:.:::      :|.::.:.
plant   390 --------------LEKRMKEKDEMIN--------------THNEKMSIMQ------QTARDYLA 420

  Fly   420 KRLEEADKG---LERARNSVDKNLKHIDYLEGELKEARELIVHLEQRPDAMDAGVKEKDLIIADL 481
            ...||.:|.   ||..|...:....::|..:.:.|..|.
plant   421 SIYEEHEKASQHLEAQRKEYEDRENYLDKCQAKNKTERR-------------------------- 459

  Fly   482 KLQLQSLEQHKKVMNKQVANTIKQHADFEELGGNYKEALQQISDLRETLSVTNAKLEMQSKLEVQ 546
            |||.|   :||.:|..|..|  |...|...|.   ::..::..:||:.:.....|::.:..||:
plant   460 KLQWQ---KHKNLMATQEQN--KADEDMMRLA---EQQQREKDELRKQVRELEEKIDAEQALEL- 515

  Fly   547 LRKEVSKMREQMVIDQKLLNARSELIATLQKNE-EDSRTKLDQMYYQVSEKETLINQVNNKLSSK 610
               |:.:||..:           :::..:|:.| |||:.|            .:|.:...:|..|
plant   516 ---EIERMRGDL-----------QVMGHMQEGEGEDSKIK------------EMIEKTKEELKEK 554

  Fly   611 EEEF---YNLYGTLTHKQREVRRQEHIIKLLKEQNSRVSLLRANQD---------ERNATMEEEI 663
            ||::   .:||.||..|        |.....:.|::|.:|:|:.::         :|...: :|.
plant   555 EEDWEYQESLYQTLVVK--------HGYTNDELQDARKALIRSMRELTTRAYIGVKRMGAL-DET 610

  Fly   664 KHLKNALRNYAKLIVGNMGEHFFEVLPAGEMESIRSGGHPVRV---DSSCKFLQEPNLQEPNLQE 725
            ...|.|...|..:......|   |:....|.....|..||::|   |...|  :|.|.::..|||
plant   611 PFKKVAKEKYPAVEADKKAE---ELCSLWEEHLGDSAWHPIKVVEKDGIAK--EELNEEDEKLQE 670

Fly 726 725
plant 671 670

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
salto	NP_610756.2	DUF1640	<313..422	CDD:285090	8/108 (7%)
		BAR	<518..670	CDD:299863	32/164 (20%)
		YjbI	<713..803	CDD:224276	5/13 (38%)
FDM4	NP_001318996.1	zf-XS	34..76	CDD:251981
		XS	216..330	CDD:397506	22/120 (18%)
		COG5281	<301..>543	CDD:227606	67/395 (17%)
		XH	602..726	CDD:397507	19/75 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000