Protein Alignment CG8850 and Slc6a11

DIOPT Version :10

• Sequence 1: NP_725122.2
• Gene: CG8850 / 36331
• FlyBaseID: FBgn0033708
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_077348.1
• Gene: Slc6a11 / 79213
• RGDID: 628737
• Length: 627
• Species: Rattus norvegicus
• Alignment Length: 558
• Identity: 208/558 - (37%)
• Similarity: 315/558 - (56%)
• Gaps: 17/558 - (3%)

  Fly    48 EAESESSGQRDQWSRGVEFLFSCIALSVGLGNVWRFPFIALENGGGAFLIPYVIVLLLIGRPVYY 112
            ||..::..:|..|:..|||:.|.....:|||||||||::..:|||||||||||:..:..|.||::
  Rat    36 EARDKAVHERGHWNNKVEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFLIPYVVFFICCGIPVFF 100

  Fly   113 LEVIIGQFSSRGCIRAF-DMAPIMRGIAYGQVYSTALATTYYACIMALTIRYLVASFSEVLPWTY 176
            ||..:|||:|.|.|..: .:.|:..||.|......|....||..|:|..|.||...|:..|||..
  Rat   101 LETALGQFTSEGGITCWRRVCPLFEGIGYATQVIEAHLNVYYIIILAWAIFYLSNCFTTELPWAT 165

  Fly   177 CLVEWG-KSCVA-TGATAANDSSI-VQGVSSAEL-FFTQTVLREPESLDDNGLGTPSWDLVLCLL 237
            |..||. :.||. .....:|.|.: :|..:|..: |:.:.||...:.::.  :|...|:|.||||
  Rat   166 CGHEWNTEKCVEFQKLNFSNYSHVSLQNATSPVMEFWERRVLAISDGIEH--IGNLRWELALCLL 228

  Fly   238 ATWVIIGTILSKGIRSSGKASYFLALFPYVIMIVLLIRAVTLPGAWQGIVYFLKPQWSQLLNPHV 302
            |.|.|....:.||.:|:||..|..|.|||:::::||||.||||||.:||.::|.|..|:|.:|.|
  Rat   229 AAWTICYFCIWKGTKSTGKVVYVTATFPYIMLLILLIRGVTLPGASEGIKFYLYPDLSRLSDPQV 293

  Fly   303 WYAAITQMFFSLAICFGTLVMYASFNDFNKNVHKDVIIITTIDSLTSILAGCIIFGILGNLAFET 367
            |..|.||:|||.|||.|.|....|:|::|.|.::|.|::..::|.||.:||..||.:||.:|:|.
  Rat   294 WVDAGTQIFFSYAICLGCLTALGSYNNYNNNCYRDCIMLCCLNSGTSFVAGFAIFSVLGFMAYEQ 358

  Fly   368 NTKDISQVVKGGAGLAFISYPEAIAKFKYLPQLFAVLFFFMLLVLGIGSNIGMASAVVNVVKDRF 432
            .. .|::|.:.|.|||||:||:|:......| |:|.|||.||:.||:.|......::|..|.|.:
  Rat   359 GV-PIAEVAESGPGLAFIAYPKAVTMMPLSP-LWATLFFMMLIFLGLDSQFVCVESLVTAVVDMY 421

  Fly   433 THL-----PHWLLAVSASIIGFLCGLVYMTPGGQFVLNLVDFYGCTFIALV-LAIAELLAVGWIY 491
            ..:     ...||.::.||:.:..|||.:|.||.::..|.|.|..:.:.|: :||.|.:.:||:|
  Rat   422 PKVFRRGYRRELLILALSIVSYFLGLVMLTEGGMYIFQLFDSYAASGMCLLFVAIFECVCIGWVY 486

  Fly   492 GVKRICSDIEFMLNVKTSFYWRICWAIVAPGLMFLVLVYMLFSYEPLTYRGV-QYPPVYYMAGWI 555
            |..|...:||.|:..:.....:.||.:|.||:...:.::.|..|:||.|..| .||...|..||:
  Rat   487 GSNRFYDNIEDMIGYRPLSLIKWCWKVVTPGICAGIFIFFLVKYKPLKYNNVYTYPAWGYGIGWL 551

  Fly   556 IWGLGVLQLPFWALVTIYQQPGKTFGSKFGLAMQPTAN 593
            :....:|.:|.|..:.:::..| |...|......|:|:
  Rat   552 MALSSMLCIPLWIFIKLWKTEG-TLPEKLQKLTVPSAD 588

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8850	NP_725122.2	SLC6sbd	58..532	CDD:271359	186/484 (38%)
Slc6a11	NP_077348.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..36		208/558 (37%)
		SLC6sbd_GAT3	44..585	CDD:212077	204/545 (37%)